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The map label for this gene is intE [H]

Identifier: 238894186

GI number: 238894186

Start: 2089612

End: 2090754

Strand: Reverse

Name: intE [H]

Synonym: KP1_2147

Alternate gene names: 238894186

Gene position: 2090754-2089612 (Counterclockwise)

Preceding gene: 238894187

Following gene: 238894184

Centisome position: 39.84

GC content: 43.48

Gene sequence:

>1143_bases
ATGGCAGCTAGACCGCGTACCCATAAAATCACTATTCCAAACCTATATTGCAAACTTGATAAACGTACCGGAAAGGTTTA
CTGGCAATACAAACACCCTATCTCTGGTCGTTTTCATAGCCTCGGCACGGACGAAGCTGAAGCAAAGCAGGTGGCAAGTG
AAGCAAATACGATTATTGCAGAGCAGCGCACCAGGCAGATCCTTGGTATTAACGAGCGTCTGGCTCGCATGAAAGGAAAC
CGCACGGATATTACAGTTTCTTCATGGCTCGACAAATATGAATTGGTGCAGGAGGAAAGATTGAAACACAACGAGCTACG
TCCAAACTCTTTTCGACAGAAAGCTAAACCAATCCGTCTTTTTCGTGAACATTGTGGTATGCAATATCTAAAAGATATAA
CAGCACTTGATATTTCCGAAATAACAGATGCTGTTAAGGCAGAGGGTCATAACAGGATGGCTCAAGTTGTACGCATGGTA
CTAATAGATGTTTTTAAAGAGGCTCAACATGCTGGTCACGTTCCACCAGGATACAACCCTGCCCAAGCAACGAAACAGCC
ACGAAATAAGATAAGCAGACAAAGGCTATCTCTGGAGGAATGGGAGGCTATTTATACATCTGCCGAACAACAACAACCTT
ATTTGCAATGTGGAATGTTGCTTGCCATTGTAACAGGGCAACGCCTTGGAGATATTTGCAATATGAGGTTTTCGGATGTA
TGGGATGATATGCTGCATATTGAGCAGGAGAAAACAGGAACTCGTTTAGCCATTCCCCTTTCTCTCAGAAATGAAGCGTT
AAATATTACTCTGAGTGATGTTATTTCAAAATGTAGAGATGCTGTGGTGAGTAAATACCTTGTTCATTTTCGCCATAGCA
CCTCACAGGCTAGTCGTGGTGACCAAGTGTCAGCCAAAACACTTACTTCAACGTTCAAGAAAGCACGGGATAAAAGCGGT
CTCACATGGGAAGAGGGAACAGCACCGACTTTCCATGAACAGAGATCTCTTTCCGAGCGCTTGTATCGTGAGCAAGGGAT
AGACACCCAGAAACTATTGGGCCACAAAACAATGAAAATGACTGACAGATACAATGATGATCGCGGTAAAGAGTGGATCG
TTGTTGGTAAAAAAGCAGTATGA

Upstream 100 bases:

>100_bases
CGGCGCTGGATGGTTGATAAAGAAGCTCGTTTTATAGGTGTAGTTGCTGAACCTCAACTTCCAATACATGTTAACCCAAA
ACTGAGACGGATAATTAGCG

Downstream 100 bases:

>100_bases
TCTTCAATCAGTTTTGGGGAAGAATTTTGGGGAAGTTTTGGGGAAGCCTCCGCACACTCCAAAAAAAACGGGAGCCCATC
GGCTCCCGCTTTTACTTAAT

Product: prophage lambda integrase

Products: NA

Alternate protein names: Int(Lambda); Prophage e14 integrase [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MAARPRTHKITIPNLYCKLDKRTGKVYWQYKHPISGRFHSLGTDEAEAKQVASEANTIIAEQRTRQILGINERLARMKGN
RTDITVSSWLDKYELVQEERLKHNELRPNSFRQKAKPIRLFREHCGMQYLKDITALDISEITDAVKAEGHNRMAQVVRMV
LIDVFKEAQHAGHVPPGYNPAQATKQPRNKISRQRLSLEEWEAIYTSAEQQQPYLQCGMLLAIVTGQRLGDICNMRFSDV
WDDMLHIEQEKTGTRLAIPLSLRNEALNITLSDVISKCRDAVVSKYLVHFRHSTSQASRGDQVSAKTLTSTFKKARDKSG
LTWEEGTAPTFHEQRSLSERLYREQGIDTQKLLGHKTMKMTDRYNDDRGKEWIVVGKKAV

Sequences:

>Translated_380_residues
MAARPRTHKITIPNLYCKLDKRTGKVYWQYKHPISGRFHSLGTDEAEAKQVASEANTIIAEQRTRQILGINERLARMKGN
RTDITVSSWLDKYELVQEERLKHNELRPNSFRQKAKPIRLFREHCGMQYLKDITALDISEITDAVKAEGHNRMAQVVRMV
LIDVFKEAQHAGHVPPGYNPAQATKQPRNKISRQRLSLEEWEAIYTSAEQQQPYLQCGMLLAIVTGQRLGDICNMRFSDV
WDDMLHIEQEKTGTRLAIPLSLRNEALNITLSDVISKCRDAVVSKYLVHFRHSTSQASRGDQVSAKTLTSTFKKARDKSG
LTWEEGTAPTFHEQRSLSERLYREQGIDTQKLLGHKTMKMTDRYNDDRGKEWIVVGKKAV
>Mature_379_residues
AARPRTHKITIPNLYCKLDKRTGKVYWQYKHPISGRFHSLGTDEAEAKQVASEANTIIAEQRTRQILGINERLARMKGNR
TDITVSSWLDKYELVQEERLKHNELRPNSFRQKAKPIRLFREHCGMQYLKDITALDISEITDAVKAEGHNRMAQVVRMVL
IDVFKEAQHAGHVPPGYNPAQATKQPRNKISRQRLSLEEWEAIYTSAEQQQPYLQCGMLLAIVTGQRLGDICNMRFSDVW
DDMLHIEQEKTGTRLAIPLSLRNEALNITLSDVISKCRDAVVSKYLVHFRHSTSQASRGDQVSAKTLTSTFKKARDKSGL
TWEEGTAPTFHEQRSLSERLYREQGIDTQKLLGHKTMKMTDRYNDDRGKEWIVVGKKAV

Specific function: Integrase from the cryptic lambdoic prophage e14. Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the h

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1787386, Length=372, Percent_Identity=61.2903225806452, Blast_Score=472, Evalue=1e-134,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016177
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR015094
- InterPro:   IPR023109
- InterPro:   IPR013087 [H]

Pfam domain/function: PF09003 Phage_integ_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 43657; Mature: 43526

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARPRTHKITIPNLYCKLDKRTGKVYWQYKHPISGRFHSLGTDEAEAKQVASEANTIIA
CCCCCCCCEEECCHHEEEEECCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
EQRTRQILGINERLARMKGNRTDITVSSWLDKYELVQEERLKHNELRPNSFRQKAKPIRL
HHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FREHCGMQYLKDITALDISEITDAVKAEGHNRMAQVVRMVLIDVFKEAQHAGHVPPGYNP
HHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
AQATKQPRNKISRQRLSLEEWEAIYTSAEQQQPYLQCGMLLAIVTGQRLGDICNMRFSDV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
WDDMLHIEQEKTGTRLAIPLSLRNEALNITLSDVISKCRDAVVSKYLVHFRHSTSQASRG
HHHHHHHHHHCCCCEEEEEEEECCCHHEEEHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
DQVSAKTLTSTFKKARDKSGLTWEEGTAPTFHEQRSLSERLYREQGIDTQKLLGHKTMKM
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCHHHHH
TDRYNDDRGKEWIVVGKKAV
HHCCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
AARPRTHKITIPNLYCKLDKRTGKVYWQYKHPISGRFHSLGTDEAEAKQVASEANTIIA
CCCCCCCEEECCHHEEEEECCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
EQRTRQILGINERLARMKGNRTDITVSSWLDKYELVQEERLKHNELRPNSFRQKAKPIRL
HHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FREHCGMQYLKDITALDISEITDAVKAEGHNRMAQVVRMVLIDVFKEAQHAGHVPPGYNP
HHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
AQATKQPRNKISRQRLSLEEWEAIYTSAEQQQPYLQCGMLLAIVTGQRLGDICNMRFSDV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
WDDMLHIEQEKTGTRLAIPLSLRNEALNITLSDVISKCRDAVVSKYLVHFRHSTSQASRG
HHHHHHHHHHCCCCEEEEEEEECCCHHEEEHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
DQVSAKTLTSTFKKARDKSGLTWEEGTAPTFHEQRSLSERLYREQGIDTQKLLGHKTMKM
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCHHHHH
TDRYNDDRGKEWIVVGKKAV
HHCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]