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The map label for this gene is potC [H]

Identifier: 238894168

GI number: 238894168

Start: 2072105

End: 2072890

Strand: Reverse

Name: potC [H]

Synonym: KP1_2128

Alternate gene names: 238894168

Gene position: 2072890-2072105 (Counterclockwise)

Preceding gene: 238894169

Following gene: 238894167

Centisome position: 39.49

GC content: 56.23

Gene sequence:

>786_bases
ATGATCGGTCGACTGCTGCGCGGCGGCTTTATGACCGCCATCTACGCGTATCTCTACATCCCTATTATTATTCTGATCGT
TAACTCGTTTAACCGGTCGCGCTTCGGCATCAACTGGCAGGGGTTCACCACCGACTGGTATAGCCTGCTGATGAACAACG
ATAGCCTGCTGCAGGCCGCCCAGCACTCGCTGACCATGGCGGTGCTGTCGGCGACCTTCGCCACCCTTATCGGCTCGCTG
ACCGCCGTGGCGCTGTACCGTTACCGCTTTCGCGGCAAACCGTTTGTCAGCGGCATGCTGTTTGTGGTGATGATGTCGCC
AGATATTGTGATGGCCATCTCTCTGCTGGTGCTGTTTATGCTGATCGGCGTCCAGCTTGGTTTCTGGTCGCTGCTGTTTT
CGCATATCACCTTCTGCCTGCCGTTTGTGGTGGTCACCGTTTACTCCCGCCTGAAAGGCTTTGACGTGCGGATGCTGGAG
GCGGCGAAAGATCTGGGCGCCAGCGAGATGACCATCCTGCGCAAAATTATCCTGCCGCTGGCCCTGCCGGCGGTAGCCGC
TGGGTGGTTGCTGAGCTTTACCCTGTCGATGGATGACGTGGTAGTCTCCTCGTTCGTGACCGGTCCGGGGTATGAAATCC
TGCCACTGAAGATCTATTCGATGGTCAAGGTTGGCGTTTCGCCAGAGGTGAACGCCCTGGCCACGATTTTGTTGGTTCTG
TCGCTGGTGATGGTCATCGCCAGTCAGTTAATTGCACGTGATAAAACTCAGGGGACGTTAAAATGA

Upstream 100 bases:

>100_bases
TCGGCGCGGCAACCAGCATTACCTTAACCCTGGTGATGGGCCTGATGCTGTTGATTTACTGGCGCGCGGCGCGCCTGCTG
AATAAAAAGGTGGAGCTGGA

Downstream 100 bases:

>100_bases
AAAAATGGTCACGCCACCTGCTCGCGGCGAGCGCTCTGGCAATCGGCATGGGCGCTGCGCACGCGGACGATAGCAAAACG
CTCTATTTCTATAACTGGAC

Product: spermidine/putrescine ABC transporter membrane protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNRSRFGINWQGFTTDWYSLLMNNDSLLQAAQHSLTMAVLSATFATLIGSL
TAVALYRYRFRGKPFVSGMLFVVMMSPDIVMAISLLVLFMLIGVQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLE
AAKDLGASEMTILRKIILPLALPAVAAGWLLSFTLSMDDVVVSSFVTGPGYEILPLKIYSMVKVGVSPEVNALATILLVL
SLVMVIASQLIARDKTQGTLK

Sequences:

>Translated_261_residues
MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNRSRFGINWQGFTTDWYSLLMNNDSLLQAAQHSLTMAVLSATFATLIGSL
TAVALYRYRFRGKPFVSGMLFVVMMSPDIVMAISLLVLFMLIGVQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLE
AAKDLGASEMTILRKIILPLALPAVAAGWLLSFTLSMDDVVVSSFVTGPGYEILPLKIYSMVKVGVSPEVNALATILLVL
SLVMVIASQLIARDKTQGTLK
>Mature_261_residues
MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNRSRFGINWQGFTTDWYSLLMNNDSLLQAAQHSLTMAVLSATFATLIGSL
TAVALYRYRFRGKPFVSGMLFVVMMSPDIVMAISLLVLFMLIGVQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLE
AAKDLGASEMTILRKIILPLALPAVAAGWLLSFTLSMDDVVVSSFVTGPGYEILPLKIYSMVKVGVSPEVNALATILLVL
SLVMVIASQLIARDKTQGTLK

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=259, Percent_Identity=95.7528957528958, Blast_Score=475, Evalue=1e-135,
Organism=Escherichia coli, GI1787081, Length=251, Percent_Identity=40.2390438247012, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1787714, Length=245, Percent_Identity=30.2040816326531, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787713, Length=116, Percent_Identity=31.8965517241379, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788764, Length=207, Percent_Identity=28.0193236714976, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28797; Mature: 28797

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]