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The map label for this gene is yceL [H]

Identifier: 238894112

GI number: 238894112

Start: 2011375

End: 2012748

Strand: Reverse

Name: yceL [H]

Synonym: KP1_2065

Alternate gene names: 238894112

Gene position: 2012748-2011375 (Counterclockwise)

Preceding gene: 238894117

Following gene: 238894111

Centisome position: 38.35

GC content: 59.9

Gene sequence:

>1374_bases
GTGAAAACAGCAACATACCATTTTCTGCGCCATCTCCTCTTTTCGATGAATAGGCTCAATCGATCTTGCTTTTTGATAAA
AAAATATTGTCGCAAGGGTGCTGGGAAAAGCAGCAGATTGCCCGCAGAATATCCTCGCTTATCTCTATTTTTCCCTGGAG
GGGAAATGTCCCGCGTCTCGCAGGCAAGGAGCCTGGGTAAATATTTCCTGTTAGTCGATAACATGCTGGTCGTGCTGGGC
TTTTTTGTCGTTTTTCCGCTGATTTCCATCCGCTTTGTCGATCAGATGGGCTGGGCAGCGCTGATGGTCGGCATTGCGCT
CGGCCTGCGCCAGCTGGTACAGCAGGGATTAGGCATCTTTGGCGGCGCCATCGCCGACCGCTTCGGCGCGAAACCGATGA
TCGTCACCGGTATGCTGATGCGTGCCGGCGGTTTCGCGGCGATGGCCGTCGCCCATGAGCCGTGGGTGCTGTGGTTCTCG
TGCATACTCTCCGGACTCGGCGGTACACTGTTCGATCCGCCGCGGGCGGCGCTGGTGGTTAAGCTGGTGCGTCCGCATCA
GCGCGGCCGCTTTTTCTCCATCCTGATGATGCAGGATAGCGCCGGCGCGGTGATTGGCGCGCTGCTGGGCAGCTGGCTGC
TGCAGTATGATTTTCGCCTGGTGTGCAGCGCCGGCGCCGCGCTGTTTATCGCCTGCGCCGCGTTTAACGCCTGGTATCTG
CCGGCATGGAAGCTCTCGACGGTGAAAACGCCGATTCGTGAGGGGCTGGGCCGGGTGCTGCGGGACAAACGCTTCGTCAC
CTATGTCCTGACGCTGACCGGCTATTATATGCTGGCGGTACAGGTGATGCTGATGCTGCCGATCATGGTGAATGATATCG
CCGGCTCGCCGGCCGCAGTGAAATGGATGTACGCCATCGAAGCCACCATTTCGCTCACCCTGCTCTATCCTATTGCCCGT
TGGAGCGAAAAACGCTTCCGCCTTGAGCACCGGCTGATGGCCGGTCTGCTGGTGATGACCCTGGCCATGCTCCCCATCGG
GATGACCAGCAGTTTACAGCAGCTGTTTACCCTGATTTGCCTGTTTTACATCGGCTCTATCATTGCCGAACCCGCCCGCG
AGACGCTGGGCGCTTCGCTGGCGGACGCCCGGGCGCGTGGCAGCTATATGGGTTTCAGCCGTCTGGGGCTCGCCTTCGGC
GGCGCGCTGGGTTACGCGGGCGGCGGCTGGCTGTTTGATGCCGGGAAAGCCGTCGGCCAGCCCGAACTGCCGTGGCTGAT
GCTCGGCGCCATCGGGGTTATCACCTTCCTGGCGCTATGGTGGCAATTCAGTCCGAAACGCTCTGCCTCCGGTATGCTGG
AGCCGCGCACCTGA

Upstream 100 bases:

>100_bases
ACGCACCTTCGGCACGTTACTGCGATAGCCAAACATTTCCTTTTTCAGTCCCCCTGACTTCACTCTTGCTTTCATCACTA
TACCTTTCCTGCACGATAGT

Downstream 100 bases:

>100_bases
TGCGCGCGGCGGCGGTTTCTCCTGCTTTCAGCCTATTCTGCTGGCGCGATGGGTGCTGACAGGTCATGATGCTTTGTGTC
AGGATGAAGGAAGGTATGAG

Product: multidrug resistance protein MdtH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MKTATYHFLRHLLFSMNRLNRSCFLIKKYCRKGAGKSSRLPAEYPRLSLFFPGGEMSRVSQARSLGKYFLLVDNMLVVLG
FFVVFPLISIRFVDQMGWAALMVGIALGLRQLVQQGLGIFGGAIADRFGAKPMIVTGMLMRAGGFAAMAVAHEPWVLWFS
CILSGLGGTLFDPPRAALVVKLVRPHQRGRFFSILMMQDSAGAVIGALLGSWLLQYDFRLVCSAGAALFIACAAFNAWYL
PAWKLSTVKTPIREGLGRVLRDKRFVTYVLTLTGYYMLAVQVMLMLPIMVNDIAGSPAAVKWMYAIEATISLTLLYPIAR
WSEKRFRLEHRLMAGLLVMTLAMLPIGMTSSLQQLFTLICLFYIGSIIAEPARETLGASLADARARGSYMGFSRLGLAFG
GALGYAGGGWLFDAGKAVGQPELPWLMLGAIGVITFLALWWQFSPKRSASGMLEPRT

Sequences:

>Translated_457_residues
MKTATYHFLRHLLFSMNRLNRSCFLIKKYCRKGAGKSSRLPAEYPRLSLFFPGGEMSRVSQARSLGKYFLLVDNMLVVLG
FFVVFPLISIRFVDQMGWAALMVGIALGLRQLVQQGLGIFGGAIADRFGAKPMIVTGMLMRAGGFAAMAVAHEPWVLWFS
CILSGLGGTLFDPPRAALVVKLVRPHQRGRFFSILMMQDSAGAVIGALLGSWLLQYDFRLVCSAGAALFIACAAFNAWYL
PAWKLSTVKTPIREGLGRVLRDKRFVTYVLTLTGYYMLAVQVMLMLPIMVNDIAGSPAAVKWMYAIEATISLTLLYPIAR
WSEKRFRLEHRLMAGLLVMTLAMLPIGMTSSLQQLFTLICLFYIGSIIAEPARETLGASLADARARGSYMGFSRLGLAFG
GALGYAGGGWLFDAGKAVGQPELPWLMLGAIGVITFLALWWQFSPKRSASGMLEPRT
>Mature_457_residues
MKTATYHFLRHLLFSMNRLNRSCFLIKKYCRKGAGKSSRLPAEYPRLSLFFPGGEMSRVSQARSLGKYFLLVDNMLVVLG
FFVVFPLISIRFVDQMGWAALMVGIALGLRQLVQQGLGIFGGAIADRFGAKPMIVTGMLMRAGGFAAMAVAHEPWVLWFS
CILSGLGGTLFDPPRAALVVKLVRPHQRGRFFSILMMQDSAGAVIGALLGSWLLQYDFRLVCSAGAALFIACAAFNAWYL
PAWKLSTVKTPIREGLGRVLRDKRFVTYVLTLTGYYMLAVQVMLMLPIMVNDIAGSPAAVKWMYAIEATISLTLLYPIAR
WSEKRFRLEHRLMAGLLVMTLAMLPIGMTSSLQQLFTLICLFYIGSIIAEPARETLGASLADARARGSYMGFSRLGLAFG
GALGYAGGGWLFDAGKAVGQPELPWLMLGAIGVITFLALWWQFSPKRSASGMLEPRT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081828, Length=399, Percent_Identity=85.4636591478697, Blast_Score=680, Evalue=0.0,
Organism=Escherichia coli, GI87081738, Length=358, Percent_Identity=25.1396648044693, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR022855
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50310; Mature: 50310

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure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CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA