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The map label for this gene is frwC [H]

Identifier: 238894045

GI number: 238894045

Start: 1942542

End: 1943711

Strand: Reverse

Name: frwC [H]

Synonym: KP1_1992

Alternate gene names: 238894045

Gene position: 1943711-1942542 (Counterclockwise)

Preceding gene: 238894047

Following gene: 238894044

Centisome position: 37.03

GC content: 60.17

Gene sequence:

>1170_bases
ATGCACTTTTTCTCTACTGTTTTATGCGACGCCCTTTTTCTAATGTTGAGCCATCCATACTGTCACGGGCCCTACAGCGC
TCAGGAGCAAGCAATGAACGAACTGGTGCAAATACTAAAAAATACCCGCCAGCATCTGATGACCGGCGTGTCACATATGA
TCCCCTTCGTGGTCTCCGGCGGGATCCTGCTGGCGGTGTCCGTCATGTTGTATGGCAAAGGCGCGGTACCCGATGCTGCC
TCCGACCCCAACCTGAAGAAACTCTTTGATATCGGCGTCGCCGGGCTGACGTTGATGGTGCCCTTTCTCGCCGCCTACAT
CGGCTACTCCATTTCTGACCGCGCCGCGCTGGCCCCCTGCGCCATCGGCGCCTGGGTGGGCAACAGTTTTGGCGCCGGTT
TCTTCGGCGCGCTGATCGCCGGCATGATTGGCGGCCTGGTGGTCTATTACCTGAAAAAAATCCCCGTACATAAAGTTCTG
CGCTCGGTGATGCCAATTTTCATCATTCCCATCGTCGGCACCTTTATCACCGCCGGGATCATGATGTGGGGGCTTGGCGA
GCCGGTTGGCGCGCTGACCGCTAACCTGACCGGCTGGCTGCAGGGGATGCGCGAGGGCAGCATCGTGGTGCTGGCCATCA
TTATGGGTCTGATGCTGGCCTTTGATATGGGCGGCCCGGTGAACAAAGTTGCCTACGCCTTCATGCTGATTTGCGTTTCG
CAGGGCGTCTACAGCGTGGTGGCTATCGCCGCCGTCGGTATCGCCGTACCGCCGCTGGGCATGGGGCTGGCGACGCTGAT
TGGCCGCAAATATTTCACCGCCGAAGAGCGGGAAACCGGCAAAGCCGCGCTGGTGATGGGCTGTGTCGGCGTGACCGAAG
GGGCGATTCCCTTTGCCGCCGCGGATCCGCTGCGCGTCATTCCGGCCAATATGATTGGCGCCGCCAGCGGCTGCGTCACC
GCCGCGCTGATGGGCGCCCAGTGTTACGCCGGCTGGGGCGGGCTTATCGTGCTGCCGGTGGTCCAGGGCAAGCTCGGGTT
TGTTGCCGCACTGCTGGTCGGCGCCTGCGTCAGCGCTGCCTGCGTCATCCTGCTGAAAGCCTTCGCCAAAAAGAAACCCA
CTGACGTCGCCGCTGACGATGAACTGGACCTTGATTTCGAAATTAACTAA

Upstream 100 bases:

>100_bases
CCGCCATCACAATTCCACCCTGTTAGCGCTCATATCTCCTGTCATCACTAAGATTTGAGGTGGATCGCAATTCTTTTCTC
ATCTTACAAATATCCAGTAA

Downstream 100 bases:

>100_bases
CAGACTGGAAGGAACAGATTATGACCCACATTATCGCTGTCACCGCCTGCCCGTCGGGGGTGGCTCACACCTACATGGCC
GCTGAATCACTGGAAAGCGC

Product: putative fructose-like permease EIIC subunit 2

Products: NA

Alternate protein names: PTS system fructose-like EIIC component 2 [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MHFFSTVLCDALFLMLSHPYCHGPYSAQEQAMNELVQILKNTRQHLMTGVSHMIPFVVSGGILLAVSVMLYGKGAVPDAA
SDPNLKKLFDIGVAGLTLMVPFLAAYIGYSISDRAALAPCAIGAWVGNSFGAGFFGALIAGMIGGLVVYYLKKIPVHKVL
RSVMPIFIIPIVGTFITAGIMMWGLGEPVGALTANLTGWLQGMREGSIVVLAIIMGLMLAFDMGGPVNKVAYAFMLICVS
QGVYSVVAIAAVGIAVPPLGMGLATLIGRKYFTAEERETGKAALVMGCVGVTEGAIPFAAADPLRVIPANMIGAASGCVT
AALMGAQCYAGWGGLIVLPVVQGKLGFVAALLVGACVSAACVILLKAFAKKKPTDVAADDELDLDFEIN

Sequences:

>Translated_389_residues
MHFFSTVLCDALFLMLSHPYCHGPYSAQEQAMNELVQILKNTRQHLMTGVSHMIPFVVSGGILLAVSVMLYGKGAVPDAA
SDPNLKKLFDIGVAGLTLMVPFLAAYIGYSISDRAALAPCAIGAWVGNSFGAGFFGALIAGMIGGLVVYYLKKIPVHKVL
RSVMPIFIIPIVGTFITAGIMMWGLGEPVGALTANLTGWLQGMREGSIVVLAIIMGLMLAFDMGGPVNKVAYAFMLICVS
QGVYSVVAIAAVGIAVPPLGMGLATLIGRKYFTAEERETGKAALVMGCVGVTEGAIPFAAADPLRVIPANMIGAASGCVT
AALMGAQCYAGWGGLIVLPVVQGKLGFVAALLVGACVSAACVILLKAFAKKKPTDVAADDELDLDFEIN
>Mature_389_residues
MHFFSTVLCDALFLMLSHPYCHGPYSAQEQAMNELVQILKNTRQHLMTGVSHMIPFVVSGGILLAVSVMLYGKGAVPDAA
SDPNLKKLFDIGVAGLTLMVPFLAAYIGYSISDRAALAPCAIGAWVGNSFGAGFFGALIAGMIGGLVVYYLKKIPVHKVL
RSVMPIFIIPIVGTFITAGIMMWGLGEPVGALTANLTGWLQGMREGSIVVLAIIMGLMLAFDMGGPVNKVAYAFMLICVS
QGVYSVVAIAAVGIAVPPLGMGLATLIGRKYFTAEERETGKAALVMGCVGVTEGAIPFAAADPLRVIPANMIGAASGCVT
AALMGAQCYAGWGGLIVLPVVQGKLGFVAALLVGACVSAACVILLKAFAKKKPTDVAADDELDLDFEIN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790386, Length=359, Percent_Identity=85.2367688022284, Blast_Score=575, Evalue=1e-165,
Organism=Escherichia coli, GI1788492, Length=368, Percent_Identity=38.5869565217391, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI1786951, Length=360, Percent_Identity=34.4444444444444, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI87082348, Length=381, Percent_Identity=32.2834645669291, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788729, Length=406, Percent_Identity=26.3546798029557, Blast_Score=112, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013014
- InterPro:   IPR006327 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 40466; Mature: 40466

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCCCCCCCCCCEEECC
>Mature Secondary Structure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HHHHHHHHHCCCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7773398 [H]