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The map label for this gene is aroA [H]

Identifier: 238893965

GI number: 238893965

Start: 1853448

End: 1854731

Strand: Direct

Name: aroA [H]

Synonym: KP1_1907

Alternate gene names: 238893965

Gene position: 1853448-1854731 (Clockwise)

Preceding gene: 238893964

Following gene: 238893966

Centisome position: 35.31

GC content: 61.37

Gene sequence:

>1284_bases
ATGGAATCCCTGACGTTACAACCCATCGCACGCGTAGAGGGCACCGTGAACCTGCCAGGTTCGAAAAGCGTCTCCAACCG
CGCGCTGCTGCTGGCTGCCCTGGCCCGCGGCACGACGGTGCTGACCAACCTGCTGGACAGCGACGATGTGCGCCATATGC
TGAATGCCCTGAGTGCGCTGGGGGTTCAATATACCCTGTCTGCCGACCGCACCCGCTGCGAAGTGATCGGCAACGGCGGC
CCGTTGCGCTCTGCCGCGGCGCTGGAGCTGTTCCTTGGCAACGCCGGTACCGCGATGCGTCCGCTGGCGGCGGCCCTGTG
CCTTGGCAGCAACGATATCGTGCTGACCGGCGAACCGCGGATGAAAGAGCGTCCGATCGGCCATCTGGTGGATGCCCTGC
GTCAGGGCGGCGCTCAGATCGACTATCTGGAGCAGGAAAATTATCCACCGCTGCGCCTGCGCGGCGGTTTTCAGGGCGGC
AACGTCGAGGTTGACGGCAGCGTCTCCAGCCAGTTCCTGACCGCGCTGCTGATGACCGCGCCGCTGGCGCCGCAGGATAC
CGTCATCGTCATTAAGGGCGATCTGGTGTCGAAACCCTATATCGACATTACGCTGCACCTGATGAAAACCTTCGGCGTTG
AGGTGGACAATCAGTCTTATCAGCGATTTGTGGTGCGCGGCAAGCAGCAGTATCAGTCGCCGGGAGATTACCTGGTGGAA
GGCGATGCTTCCTCGGCCTCGTATTTCCTCGCCGCTGGCGCCATTAAGGGCGGCACGGTAAAAGTCACCGGTATCGGCCG
CAACAGCGTACAGGGCGACATTCGTTTCGCCGACGTACTGGAGAAAATGGGCGCCACCGTCACCTGGGGCGACGATTTCA
TCGCCTGCACCCACGGCGAGCTCAAGGCGGTCGATATGGATATGAACCATATCCCGGACGCCGCGATGACCATCGCCACC
GCCGCGCTGTTCGCGCAAGGGACCACTACCCTGCGCAATATCTACAACTGGCGGGTCAAGGAGACGGACCGTCTGTTCGC
CATGGCGACCGAGCTGCGTAAAGTGGGCGCCGAGGTGGAAGAGGGGGAAGATTATATCCGCATCACCCCGCCGGCAAAGT
TGAAGTACGCAGAAATCGGCACCTATAACGACCACCGGATGGCGATGTGCTTCTCGCTGGTAGCGCTGTCTGATACGCCG
GTGACCATCCTTGATCCCAAATGTACGGCCAAAACGTTCCCTGACTACTTTGAGCAGCTGGCGCGGATCAGTACCCTCGC
CTGA

Upstream 100 bases:

>100_bases
CTGGACTTCGAACGCCGCCACGGTTAATCGCCTGTTTCTTTCTTCCTCCCCGCGGCCTGTCTGCGGGGTTTTTATTCTGT
TTGTTTGAGAGTGAAGTTTG

Downstream 100 bases:

>100_bases
GTAAAACTTTGTCATCCCGCGGGCTGATGTCCTGTCAGCCCGCTATAATTGCGCAAAACTTCTGCTTTTCATTTCCTGTA
GTCCGTAATTTACAAGCAAT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MESLTLQPIARVEGTVNLPGSKSVSNRALLLAALARGTTVLTNLLDSDDVRHMLNALSALGVQYTLSADRTRCEVIGNGG
PLRSAAALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAQIDYLEQENYPPLRLRGGFQGG
NVEVDGSVSSQFLTALLMTAPLAPQDTVIVIKGDLVSKPYIDITLHLMKTFGVEVDNQSYQRFVVRGKQQYQSPGDYLVE
GDASSASYFLAAGAIKGGTVKVTGIGRNSVQGDIRFADVLEKMGATVTWGDDFIACTHGELKAVDMDMNHIPDAAMTIAT
AALFAQGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGEDYIRITPPAKLKYAEIGTYNDHRMAMCFSLVALSDTP
VTILDPKCTAKTFPDYFEQLARISTLA

Sequences:

>Translated_427_residues
MESLTLQPIARVEGTVNLPGSKSVSNRALLLAALARGTTVLTNLLDSDDVRHMLNALSALGVQYTLSADRTRCEVIGNGG
PLRSAAALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAQIDYLEQENYPPLRLRGGFQGG
NVEVDGSVSSQFLTALLMTAPLAPQDTVIVIKGDLVSKPYIDITLHLMKTFGVEVDNQSYQRFVVRGKQQYQSPGDYLVE
GDASSASYFLAAGAIKGGTVKVTGIGRNSVQGDIRFADVLEKMGATVTWGDDFIACTHGELKAVDMDMNHIPDAAMTIAT
AALFAQGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGEDYIRITPPAKLKYAEIGTYNDHRMAMCFSLVALSDTP
VTILDPKCTAKTFPDYFEQLARISTLA
>Mature_427_residues
MESLTLQPIARVEGTVNLPGSKSVSNRALLLAALARGTTVLTNLLDSDDVRHMLNALSALGVQYTLSADRTRCEVIGNGG
PLRSAAALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAQIDYLEQENYPPLRLRGGFQGG
NVEVDGSVSSQFLTALLMTAPLAPQDTVIVIKGDLVSKPYIDITLHLMKTFGVEVDNQSYQRFVVRGKQQYQSPGDYLVE
GDASSASYFLAAGAIKGGTVKVTGIGRNSVQGDIRFADVLEKMGATVTWGDDFIACTHGELKAVDMDMNHIPDAAMTIAT
AALFAQGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGEDYIRITPPAKLKYAEIGTYNDHRMAMCFSLVALSDTP
VTILDPKCTAKTFPDYFEQLARISTLA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=427, Percent_Identity=89.4613583138173, Blast_Score=780, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320332, Length=446, Percent_Identity=39.9103139013453, Blast_Score=269, Evalue=8e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46111; Mature: 46111

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLTLQPIARVEGTVNLPGSKSVSNRALLLAALARGTTVLTNLLDSDDVRHMLNALSAL
CCCCCCCHHHHCCCEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHC
GVQYTLSADRTRCEVIGNGGPLRSAAALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPR
CEEEEECCCCEEEEEEECCCCCCHHHEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCC
MKERPIGHLVDALRQGGAQIDYLEQENYPPLRLRGGFQGGNVEVDGSVSSQFLTALLMTA
CCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCCCCEEECCCHHHHHHHHHHHHC
PLAPQDTVIVIKGDLVSKPYIDITLHLMKTFGVEVDNQSYQRFVVRGKQQYQSPGDYLVE
CCCCCCEEEEEECCCCCCCCHHHHHEEHHHHCCEECCCHHHHHHHHCHHHHCCCCCEEEE
GDASSASYFLAAGAIKGGTVKVTGIGRNSVQGDIRFADVLEKMGATVTWGDDFIACTHGE
CCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCEEEECCCEEEEECCC
LKAVDMDMNHIPDAAMTIATAALFAQGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVE
EEEEECCHHHCCHHHHHHHHHHHHHCCCHHHHHHHCCEECCCHHHHHHHHHHHHHCCCCC
EGEDYIRITPPAKLKYAEIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQL
CCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHH
ARISTLA
HHHHCCC
>Mature Secondary Structure
MESLTLQPIARVEGTVNLPGSKSVSNRALLLAALARGTTVLTNLLDSDDVRHMLNALSAL
CCCCCCCHHHHCCCEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHC
GVQYTLSADRTRCEVIGNGGPLRSAAALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPR
CEEEEECCCCEEEEEEECCCCCCHHHEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCC
MKERPIGHLVDALRQGGAQIDYLEQENYPPLRLRGGFQGGNVEVDGSVSSQFLTALLMTA
CCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCCCCEEECCCHHHHHHHHHHHHC
PLAPQDTVIVIKGDLVSKPYIDITLHLMKTFGVEVDNQSYQRFVVRGKQQYQSPGDYLVE
CCCCCCEEEEEECCCCCCCCHHHHHEEHHHHCCEECCCHHHHHHHHCHHHHCCCCCEEEE
GDASSASYFLAAGAIKGGTVKVTGIGRNSVQGDIRFADVLEKMGATVTWGDDFIACTHGE
CCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCEEEECCCEEEEECCC
LKAVDMDMNHIPDAAMTIATAALFAQGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVE
EEEEECCHHHCCHHHHHHHHHHHHHCCCHHHHHHHCCEECCCHHHHHHHHHHHHHCCCCC
EGEDYIRITPPAKLKYAEIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQL
CCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHH
ARISTLA
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA