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The map label for this gene is serC [H]

Identifier: 238893964

GI number: 238893964

Start: 1852286

End: 1853374

Strand: Direct

Name: serC [H]

Synonym: KP1_1906

Alternate gene names: 238893964

Gene position: 1852286-1853374 (Clockwise)

Preceding gene: 238893963

Following gene: 238893965

Centisome position: 35.29

GC content: 58.49

Gene sequence:

>1089_bases
ATGGCTCAGGTCTATAACTTCAGTTCGGGCCCGGCAATGCTGCCGGCGGAAGTACTCAAACTGGCGCAGCAGGAACTGTG
CGACTGGCACGGTCTGGGGACGTCGGTCATGGAGATCAGTCACCGTGGTAAGGAGTTTATCCAGGTGGCAGAAGCGGCAG
AACAGGACTTCCGCGCTCTGCTGAACATCCCTTCCAACTATAAAGTTTTATTCTGCCACGGCGGCGGCCGCGGCCAGTTC
GCCGGGATCCCGCTGAACATCCTCGGCGATAAAAAGGTCGCTGACTATGTGGACGCCGGCTACTGGGCGGCCAGCGCGGT
CAAAGAGGCGAAGAAATACTGCACGCCGAACGTTATCGACGCGAAAATCACCGTCGACGGCAAGCGCGCTGTGAAGCCGA
TGAGCGAGTGGCAGCTGACCCCGGGGGCGGCCTATCTGCACTACTGCCCGAACGAAACCATTGATGGTATCGCGATTGAT
GAGACGCCGAACTTCGGCGACGACGTCATCGTGACCGCCGATTTCTCCTCCACCATTCTTTCCCGCGAAATTGACGTCAA
CCGCTTCGGCGTAATCTACGCCGGCGCGCAGAAGAATATCGGTCCGGCTGGGCTGACGCTGGTCATCGTGCGTGAAGATC
TGCTGGGCAAAGCCAGCGTGGCCTGCCCATCAATTCTTGACTACACCGTGTTAAGCGAGAATGACTCGATGTTTAACACA
CCGCCGACGTTCGCATGGTATCTGGCTGGACTGGTGTTTAAGTGGCTGAAACAGCAGGGCGGGGTTGCCGCGATGGATAA
AATCAACCAGCAGAAAGCCGAACTGCTCTACGGCGTGATCGATAACAGCGGCTTCTATCGTAACGATGTGGCGCAGGCCA
ACCGTTCGCGTATGAACGTACCGTTCCAGCTGGCGGACAGCGCCCTGGACAAACTGTTCCTCGAAGAGTCGTTTGCTGCC
GGGCTGCACGCGCTGAAGGGCCACCGGGTGGTGGGCGGCATGCGTGCTTCCATCTACAACGCCATGCCGCTGGACGGCGT
GAAGGCGTTAACCGACTTTATGCTGGACTTCGAACGCCGCCACGGTTAA

Upstream 100 bases:

>100_bases
TGCGGACCGTGTCACTGAATGATAAAACCGATAGCCACAGGAATAACTTATGCCCGCGGCGGTTCGCGGGCAAAACAACA
TAGCAACGTGGTGAGGGGAA

Downstream 100 bases:

>100_bases
TCGCCTGTTTCTTTCTTCCTCCCCGCGGCCTGTCTGCGGGGTTTTTATTCTGTTTGTTTGAGAGTGAAGTTTGATGGAAT
CCCTGACGTTACAACCCATC

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MAQVYNFSSGPAMLPAEVLKLAQQELCDWHGLGTSVMEISHRGKEFIQVAEAAEQDFRALLNIPSNYKVLFCHGGGRGQF
AGIPLNILGDKKVADYVDAGYWAASAVKEAKKYCTPNVIDAKITVDGKRAVKPMSEWQLTPGAAYLHYCPNETIDGIAID
ETPNFGDDVIVTADFSSTILSREIDVNRFGVIYAGAQKNIGPAGLTLVIVREDLLGKASVACPSILDYTVLSENDSMFNT
PPTFAWYLAGLVFKWLKQQGGVAAMDKINQQKAELLYGVIDNSGFYRNDVAQANRSRMNVPFQLADSALDKLFLEESFAA
GLHALKGHRVVGGMRASIYNAMPLDGVKALTDFMLDFERRHG

Sequences:

>Translated_362_residues
MAQVYNFSSGPAMLPAEVLKLAQQELCDWHGLGTSVMEISHRGKEFIQVAEAAEQDFRALLNIPSNYKVLFCHGGGRGQF
AGIPLNILGDKKVADYVDAGYWAASAVKEAKKYCTPNVIDAKITVDGKRAVKPMSEWQLTPGAAYLHYCPNETIDGIAID
ETPNFGDDVIVTADFSSTILSREIDVNRFGVIYAGAQKNIGPAGLTLVIVREDLLGKASVACPSILDYTVLSENDSMFNT
PPTFAWYLAGLVFKWLKQQGGVAAMDKINQQKAELLYGVIDNSGFYRNDVAQANRSRMNVPFQLADSALDKLFLEESFAA
GLHALKGHRVVGGMRASIYNAMPLDGVKALTDFMLDFERRHG
>Mature_361_residues
AQVYNFSSGPAMLPAEVLKLAQQELCDWHGLGTSVMEISHRGKEFIQVAEAAEQDFRALLNIPSNYKVLFCHGGGRGQFA
GIPLNILGDKKVADYVDAGYWAASAVKEAKKYCTPNVIDAKITVDGKRAVKPMSEWQLTPGAAYLHYCPNETIDGIAIDE
TPNFGDDVIVTADFSSTILSREIDVNRFGVIYAGAQKNIGPAGLTLVIVREDLLGKASVACPSILDYTVLSENDSMFNTP
PTFAWYLAGLVFKWLKQQGGVAAMDKINQQKAELLYGVIDNSGFYRNDVAQANRSRMNVPFQLADSALDKLFLEESFAAG
LHALKGHRVVGGMRASIYNAMPLDGVKALTDFMLDFERRHG

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=366, Percent_Identity=47.8142076502732, Blast_Score=348, Evalue=4e-96,
Organism=Homo sapiens, GI10863955, Length=362, Percent_Identity=43.0939226519337, Blast_Score=293, Evalue=2e-79,
Organism=Escherichia coli, GI1787136, Length=362, Percent_Identity=87.0165745856354, Blast_Score=671, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17506897, Length=364, Percent_Identity=42.5824175824176, Blast_Score=296, Evalue=1e-80,
Organism=Saccharomyces cerevisiae, GI6324758, Length=385, Percent_Identity=38.1818181818182, Blast_Score=241, Evalue=9e-65,
Organism=Drosophila melanogaster, GI21356589, Length=364, Percent_Identity=49.4505494505495, Blast_Score=354, Evalue=6e-98,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39584; Mature: 39452

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQVYNFSSGPAMLPAEVLKLAQQELCDWHGLGTSVMEISHRGKEFIQVAEAAEQDFRAL
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
LNIPSNYKVLFCHGGGRGQFAGIPLNILGDKKVADYVDAGYWAASAVKEAKKYCTPNVID
HCCCCCCEEEEEECCCCCCCCCCCEEECCCCHHHHHHHCCHHHHHHHHHHHHHCCCCEEE
AKITVDGKRAVKPMSEWQLTPGAAYLHYCPNETIDGIAIDETPNFGDDVIVTADFSSTIL
EEEEECCHHHHCCHHHCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCEEEEECCHHHHH
SREIDVNRFGVIYAGAQKNIGPAGLTLVIVREDLLGKASVACPSILDYTVLSENDSMFNT
HHCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHEEEEECCCCCCCCC
PPTFAWYLAGLVFKWLKQQGGVAAMDKINQQKAELLYGVIDNSGFYRNDVAQANRSRMNV
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHCCC
PFQLADSALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLDGVKALTDFMLDFERR
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHH
HG
CC
>Mature Secondary Structure 
AQVYNFSSGPAMLPAEVLKLAQQELCDWHGLGTSVMEISHRGKEFIQVAEAAEQDFRAL
CEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
LNIPSNYKVLFCHGGGRGQFAGIPLNILGDKKVADYVDAGYWAASAVKEAKKYCTPNVID
HCCCCCCEEEEEECCCCCCCCCCCEEECCCCHHHHHHHCCHHHHHHHHHHHHHCCCCEEE
AKITVDGKRAVKPMSEWQLTPGAAYLHYCPNETIDGIAIDETPNFGDDVIVTADFSSTIL
EEEEECCHHHHCCHHHCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCEEEEECCHHHHH
SREIDVNRFGVIYAGAQKNIGPAGLTLVIVREDLLGKASVACPSILDYTVLSENDSMFNT
HHCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHEEEEECCCCCCCCC
PPTFAWYLAGLVFKWLKQQGGVAAMDKINQQKAELLYGVIDNSGFYRNDVAQANRSRMNV
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHCCC
PFQLADSALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLDGVKALTDFMLDFERR
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHH
HG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA