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The map label for this gene is fruP [H]

Identifier: 238893893

GI number: 238893893

Start: 1770580

End: 1771821

Strand: Reverse

Name: fruP [H]

Synonym: KP1_1826

Alternate gene names: 238893893

Gene position: 1771821-1770580 (Counterclockwise)

Preceding gene: 238893896

Following gene: 238893892

Centisome position: 33.76

GC content: 54.99

Gene sequence:

>1242_bases
ATGACGTCCGGTAAAAGAAACTACCTTCTGTTGAGTCTTTTCGATTTCCTCTACCTGTTCGCCTGGTCGTCGACCATGGC
TTTCTTCGTTATCTGGACCACCCAGCATCTTGGCATCAGCGCCACGAAGACCGGGCTGCTTTACTCGGTCAACGCCTTTA
TCGCCCTGCTGATGCAGCCTTTCTTCGGCTTTATCTCTGACAAGTTCGGCCTGAAAAAACGGCTTATCTGGCTGCTGGTC
GCCCTGCTCCTGCCGGTGGGCCCCTTCTTTATCTACGTTTACGCGCCGCTGCTGGTGCACAACTTTTGGTTTGGCGCCTT
GCTGGGAGGGATCTATCTGGGGATCATCTTTAACTCCGGCTGCGGAGTAATCGACTCTTATATCGATAAGATTTCCCGGC
GCTATCAGTTTGAATATGGTCGTGTGCGGATGTGGGGCTCGTTAGGCTGGGCAGCGGCGGCCTGGATTGTGGGTAAATAT
ATCGACAGCAATCCTAATCTGGCCTTCTGGCTCGCCAGCCTCGCCATTGTCATCGCCGCCATCTGCTTTATGCTAACCAA
AATTGAATTAACCGACGCCGATGTGGCGCGAAGCGAATCGCTGAAGGTCTCTCATGCCCTTGAGCTGGCGAAGAATGGTC
AGTTCTGGATGCTGCTGCTCTTTACCCTGTTCGTCACGCAGATTTACGACACCTACGATCAGCAGTTTGCCCAGTACTTC
TCGCTACAGTTCCCGACGCCGGAGGAAGGCAACCGCTGGTACGGGATCCTCGCGTCTATTCAGGTCTGCGGTGAAACCCT
GTTCCTCTGCCTGATGCCATGGTTTGTTAACCGGACCGGCGCCAAATGGGCGCTGATCATCGCCGGGCTGATCATGTCGG
TACGTATTGTCGGCTCAGCCGTGCCCCTCGGCCCGGTGTGGATTGGTGCGGTGAAAATGATGCATGCTCTGGAGAAGCCG
TTGATTCTGGTATCGGTCTTTAAATTCATCGCCGCCAACTTCGACCACAAGCTCTCTTCGACGGTCTATTTGCTGGTGCT
GTTCGTCGCCTCGATCGCCACCGCCATTTACTCTCCGCTGGCAGGCTATCTGTACGATACCATTGGCTTCGCCAACACCT
ATCTGATTCTCGGCAGCGTCGCCGGGCTCTTTACCCTGATCTCTATTTTCACGCTGCAGGATAAGCGCGAGCCGAAAGAA
CCCGGCGCCACCCCCTCCGCAGCCATTAACCCGGCGCAATAA

Upstream 100 bases:

>100_bases
AACAAATAATTAATGTAATACGTATAACATCTCAGGAAAACAGCGAACGCGGCCCGTGGATCGCTGACATTCTCTCTGCC
CATTTGCAAGGAACTGAAAC

Downstream 100 bases:

>100_bases
GTCTCTGCCCGGCAGCCACGCCGGGCTTGAGCCGCCTGCGCGCATGGCTTGTCAGAAGCGTGTCCCGCCCCTCTGCTCCG
GGGCGTGTGGGATCCGCTCT

Product: putative proton/sugar symporter

Products: Proton [Cytoplasm]; lactose [Cytoplasm] [C]

Alternate protein names: Lactose-proton symport [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MTSGKRNYLLLSLFDFLYLFAWSSTMAFFVIWTTQHLGISATKTGLLYSVNAFIALLMQPFFGFISDKFGLKKRLIWLLV
ALLLPVGPFFIYVYAPLLVHNFWFGALLGGIYLGIIFNSGCGVIDSYIDKISRRYQFEYGRVRMWGSLGWAAAAWIVGKY
IDSNPNLAFWLASLAIVIAAICFMLTKIELTDADVARSESLKVSHALELAKNGQFWMLLLFTLFVTQIYDTYDQQFAQYF
SLQFPTPEEGNRWYGILASIQVCGETLFLCLMPWFVNRTGAKWALIIAGLIMSVRIVGSAVPLGPVWIGAVKMMHALEKP
LILVSVFKFIAANFDHKLSSTVYLLVLFVASIATAIYSPLAGYLYDTIGFANTYLILGSVAGLFTLISIFTLQDKREPKE
PGATPSAAINPAQ

Sequences:

>Translated_413_residues
MTSGKRNYLLLSLFDFLYLFAWSSTMAFFVIWTTQHLGISATKTGLLYSVNAFIALLMQPFFGFISDKFGLKKRLIWLLV
ALLLPVGPFFIYVYAPLLVHNFWFGALLGGIYLGIIFNSGCGVIDSYIDKISRRYQFEYGRVRMWGSLGWAAAAWIVGKY
IDSNPNLAFWLASLAIVIAAICFMLTKIELTDADVARSESLKVSHALELAKNGQFWMLLLFTLFVTQIYDTYDQQFAQYF
SLQFPTPEEGNRWYGILASIQVCGETLFLCLMPWFVNRTGAKWALIIAGLIMSVRIVGSAVPLGPVWIGAVKMMHALEKP
LILVSVFKFIAANFDHKLSSTVYLLVLFVASIATAIYSPLAGYLYDTIGFANTYLILGSVAGLFTLISIFTLQDKREPKE
PGATPSAAINPAQ
>Mature_412_residues
TSGKRNYLLLSLFDFLYLFAWSSTMAFFVIWTTQHLGISATKTGLLYSVNAFIALLMQPFFGFISDKFGLKKRLIWLLVA
LLLPVGPFFIYVYAPLLVHNFWFGALLGGIYLGIIFNSGCGVIDSYIDKISRRYQFEYGRVRMWGSLGWAAAAWIVGKYI
DSNPNLAFWLASLAIVIAAICFMLTKIELTDADVARSESLKVSHALELAKNGQFWMLLLFTLFVTQIYDTYDQQFAQYFS
LQFPTPEEGNRWYGILASIQVCGETLFLCLMPWFVNRTGAKWALIIAGLIMSVRIVGSAVPLGPVWIGAVKMMHALEKPL
ILVSVFKFIAANFDHKLSSTVYLLVLFVASIATAIYSPLAGYLYDTIGFANTYLILGSVAGLFTLISIFTLQDKREPKEP
GATPSAAINPAQ

Specific function: Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family [H]

Homologues:

Organism=Escherichia coli, GI1786538, Length=390, Percent_Identity=39.2307692307692, Blast_Score=280, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR000576
- InterPro:   IPR018457
- InterPro:   IPR020846
- InterPro:   IPR016196 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 46125; Mature: 45994

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSGKRNYLLLSLFDFLYLFAWSSTMAFFVIWTTQHLGISATKTGLLYSVNAFIALLMQP
CCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEHHHCCCCHHHCCHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; lactose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactose [Periplasm] = Proton [Cytoplasm] + lactose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3056524 [H]