Click here to switch to the map view.

The map label for this gene is rimO [H]

Identifier: 238893892

GI number: 238893892

Start: 1769022

End: 1770347

Strand: Reverse

Name: rimO [H]

Synonym: KP1_1825

Alternate gene names: 238893892

Gene position: 1770347-1769022 (Counterclockwise)

Preceding gene: 238893893

Following gene: 238893886

Centisome position: 33.73

GC content: 59.28

Gene sequence:

>1326_bases
ATGAGCAATGTCACGCATCAGCCGAAAATCGGCTTCGTCTCCCTGGGCTGCCCGAAAAACCTCGTGGACTCAGAGCGTAT
CCTGACCGAACTGCGCACCGAAGGTTATGACGTCGTACCGACCTACGACAACGCCGATATGGTGATCGTTAACACCTGCG
GCTTTATTGATAGCGCTGTGCAGGAATCGCTGGAAGCGATCGGCGAAGCGTTGAAAGAGAACGGCAAGGTAATCGTCACC
GGCTGTCTCGGCGCGAAAGAGGATCAGATCCGCGAAGTGCATCCGAAGGTGCTGGAGATCACCGGTCCGCACAGCTATGA
GCAGGTGCTGGAGCATGTCCACCATTATACGCCGAAGCCGAAGCACAACCCGTTCCTGAGCCTGGTGCCGGAACAGGGGG
TTAAGCTGACGCCGCGCCACTACGCCTACTTAAAAATTTCTGAAGGCTGCAACCATCGCTGCACCTTCTGCATCATCCCG
TCCATGCGTGGCGATCTGGTGAGCCGTCCGATTGGCGAAGTGCTGGCCGAAGCCAAACGCCTCGCTGACGCCGGCGTGAA
AGAGCTGCTGGTGATTTCGCAGGACACCTCCGCCTACGGCGTCGACGTCAAGCACCGCACCGGCTTCCACAACGGTATGC
CGGTGAAGACCAGCATGGTCAGTCTGTGCGAAGAGCTGGCGAAGCTCGGCATCTGGGTACGCCTGCACTATGTCTACCCG
TACCCGCACGTTGACGATGTGATCCCGCTGATGGCGGAAGGCAAGATTCTGCCGTACCTCGATATTCCGCTGCAGCACGC
CAGCCCGCGTATTCTGAAGCTGATGAAGCGTCCTGGTTCTGCGGACCGTCAGCTGGCGCGCATTAAGCAGTGGCGTGAAA
TTTGCCCGGATCTGACCCTGCGCTCCACTTTTATTGTGGGCTTCCCGGGCGAAACGGAAGAAGATTTCCAGATGCTGCTC
GACTTCCTGAAAGAGGCGCGTCTCGACCGCGTCGGCTGCTTCAAGTACAGCCCGGTTGAAGGCGCTACCGCCAACGAGCT
GGCGGACCAGGTGCCGGAAGAGGTGAAAGAAGAGCGCTGGAACCGCTTTATGCAGCTGCAGCAGCAGATCTCTGCCGAGC
GTCTGCAGGAGAAAGTGGGGCGCGAAATCCTGGTGCTGGTAGATGAAGTTGATGAAGAAGGCGCCATTGGCCGCAGCATG
GCCGACGCTCCGGAAATCGACGGCGCGGTGTACCTGAACGGCGAAACCCGCGTTAAGCCGGGCGACGTGGTGCGGGTGAA
AGTCGAGCACGCCGACGAATACGACCTGTGGGGTACCCGGGTCTAG

Upstream 100 bases:

>100_bases
CGCTTTTTCACCATTAACCGCGACGGAGCTATACTCTTTTTCGCAAAGATCTGTAGAATTCCTGCCCTGACCATTCCAAT
AATTGAACACTTTTTAAGCT

Downstream 100 bases:

>100_bases
TCCAGCTTCCCGGATAGCGGCTTAGCGCATTCCCCAGCCTACGGGGTCCTCCCGTAGGCTCACCCCCCATGTCCGCGCAA
GCGCAGCGCCACGGGCAAGC

Product: ribosomal protein S12 methylthiotransferase

Products: NA

Alternate protein names: S12 MTTase; S12 methylthiotransferase; Ribosome maturation factor RimO [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSNVTHQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPTYDNADMVIVNTCGFIDSAVQESLEAIGEALKENGKVIVT
GCLGAKEDQIREVHPKVLEITGPHSYEQVLEHVHHYTPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIP
SMRGDLVSRPIGEVLAEAKRLADAGVKELLVISQDTSAYGVDVKHRTGFHNGMPVKTSMVSLCEELAKLGIWVRLHYVYP
YPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSADRQLARIKQWREICPDLTLRSTFIVGFPGETEEDFQMLL
DFLKEARLDRVGCFKYSPVEGATANELADQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVLVDEVDEEGAIGRSM
ADAPEIDGAVYLNGETRVKPGDVVRVKVEHADEYDLWGTRV

Sequences:

>Translated_441_residues
MSNVTHQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPTYDNADMVIVNTCGFIDSAVQESLEAIGEALKENGKVIVT
GCLGAKEDQIREVHPKVLEITGPHSYEQVLEHVHHYTPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIP
SMRGDLVSRPIGEVLAEAKRLADAGVKELLVISQDTSAYGVDVKHRTGFHNGMPVKTSMVSLCEELAKLGIWVRLHYVYP
YPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSADRQLARIKQWREICPDLTLRSTFIVGFPGETEEDFQMLL
DFLKEARLDRVGCFKYSPVEGATANELADQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVLVDEVDEEGAIGRSM
ADAPEIDGAVYLNGETRVKPGDVVRVKVEHADEYDLWGTRV
>Mature_440_residues
SNVTHQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPTYDNADMVIVNTCGFIDSAVQESLEAIGEALKENGKVIVTG
CLGAKEDQIREVHPKVLEITGPHSYEQVLEHVHHYTPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPS
MRGDLVSRPIGEVLAEAKRLADAGVKELLVISQDTSAYGVDVKHRTGFHNGMPVKTSMVSLCEELAKLGIWVRLHYVYPY
PHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSADRQLARIKQWREICPDLTLRSTFIVGFPGETEEDFQMLLD
FLKEARLDRVGCFKYSPVEGATANELADQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVLVDEVDEEGAIGRSMA
DAPEIDGAVYLNGETRVKPGDVVRVKVEHADEYDLWGTRV

Specific function: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 [H]

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI28872784, Length=476, Percent_Identity=26.4705882352941, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI28872782, Length=477, Percent_Identity=27.0440251572327, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI93277076, Length=409, Percent_Identity=26.6503667481663, Blast_Score=141, Evalue=2e-33,
Organism=Escherichia coli, GI1787057, Length=441, Percent_Identity=94.5578231292517, Blast_Score=868, Evalue=0.0,
Organism=Escherichia coli, GI1786882, Length=385, Percent_Identity=30.3896103896104, Blast_Score=159, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17553146, Length=472, Percent_Identity=26.4830508474576, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI71996771, Length=218, Percent_Identity=30.2752293577982, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21356207, Length=481, Percent_Identity=27.027027027027, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI19922432, Length=410, Percent_Identity=26.0975609756098, Blast_Score=112, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR012340
- InterPro:   IPR007197
- InterPro:   IPR005840
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 49568; Mature: 49437

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVTHQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPTYDNADMVIVNTCGFIDSAV
CCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEECCCHHHHHH
QESLEAIGEALKENGKVIVTGCLGAKEDQIREVHPKVLEITGPHSYEQVLEHVHHYTPKP
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCC
KHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPIGEVLAEAKR
CCCCCEEECCCCCCEECCCEEEEEEECCCCCCCEEEEEECCCCCHHHHCCHHHHHHHHHH
LADAGVKELLVISQDTSAYGVDVKHRTGFHNGMPVKTSMVSLCEELAKLGIWVRLHYVYP
HHHCCHHHEEEEECCCCCEEEEEHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEC
YPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSADRQLARIKQWREICPDLTL
CCCHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEE
RSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCFKYSPVEGATANELADQVPEEVKEERW
CCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHH
NRFMQLQQQISAERLQEKVGREILVLVDEVDEEGAIGRSMADAPEIDGAVYLNGETRVKP
HHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCEECC
GDVVRVKVEHADEYDLWGTRV
CCEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SNVTHQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPTYDNADMVIVNTCGFIDSAV
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEECCCHHHHHH
QESLEAIGEALKENGKVIVTGCLGAKEDQIREVHPKVLEITGPHSYEQVLEHVHHYTPKP
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCC
KHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPIGEVLAEAKR
CCCCCEEECCCCCCEECCCEEEEEEECCCCCCCEEEEEECCCCCHHHHCCHHHHHHHHHH
LADAGVKELLVISQDTSAYGVDVKHRTGFHNGMPVKTSMVSLCEELAKLGIWVRLHYVYP
HHHCCHHHEEEEECCCCCEEEEEHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEC
YPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSADRQLARIKQWREICPDLTL
CCCHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEE
RSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCFKYSPVEGATANELADQVPEEVKEERW
CCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHH
NRFMQLQQQISAERLQEKVGREILVLVDEVDEEGAIGRSMADAPEIDGAVYLNGETRVKP
HHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCEECC
GDVVRVKVEHADEYDLWGTRV
CCEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA