Click here to switch to the map view.

The map label for this gene is ybiN [H]

Identifier: 238893861

GI number: 238893861

Start: 1730855

End: 1731607

Strand: Direct

Name: ybiN [H]

Synonym: KP1_1793

Alternate gene names: 238893861

Gene position: 1730855-1731607 (Clockwise)

Preceding gene: 238893855

Following gene: 238893868

Centisome position: 32.98

GC content: 60.29

Gene sequence:

>753_bases
TTGAATAAAGCGCTGCTGGCGCATTTCTACGCGGTCAAACACTGGGACATTCCTGACGGCTTTCTCTGTCCGCCAGTGCC
TGGGCGGGCCGACTATATTCATCATCTGGCGGATCTGCTGGCCGGGGATAGCGGCGAGGTGCCGAAGGATGCCACGATCC
TTGATATTGGCACCGGCGCTAACCTCATCTATCCCCTGATCGGCGCTCACGAGTATGGCTGGCGCTTCACCGGCAGTGAA
ATCAACCCGCAGGCGTTCGCCAGCGCGCAGGCGATTATCAATGGCAACCCGGGCTTGACCCGGCAGATCCGCCTGCGCCG
GCAAAAAGAGAGCCAGGCTATCTTTCACGGCGTGATCCATAAAAACGAGACCTACGACGCCACGCTGTGTAATCCGCCGT
TCCATGACTCCGCAGAGAGCGCCCGGGCGGGGGGCGAGCGCAAGCGCCGCAACCTCGGACTTGGCGCCGAAAGCGGCCTC
AATTTTGGCGGTCAGCAGCAGGAGCTATGGTGCGAAGGGGGCGAAGTAGCCTTTATCTCGCAGATGATCCGCGAAAGCCA
GGCCTTCGCCCGCCAGGTGAAATGGTTTACCTCGCTGGTGTCGCGCGGCGATAATCTGCCGCCGCTCTACCGCCTGCTGA
CCGAGGTCGGCGCAGTGAAAGTGGTGAAAAAGGAGATGGCCCAGGGGCAAAAGCAAAGTCGCTTTATCGCCTGGAGCTTT
ATGGACGACGCCAAACGCCGTCGTCCATTCTAA

Upstream 100 bases:

>100_bases
CGCGCTCTGCTAGGCCCATCCTGACCTGCAGGGCTACATTACGCTCAATCCGCTGGGTGAGCAGACCATTGATTTTGCCA
ATCCGCAGGCGGTGAAGGCG

Downstream 100 bases:

>100_bases
CGCTACTCGGCGGCCGGGCTGTCGGCGCCCGGCATCGGCAGCTGCTGCCAGGTCTGTACCGGCGCGCGAACCCCGGCGCG
GTCGAAGTGCTTTTTCACCT

Product: putative SAM-dependent methyltransferase

Products: NA

Alternate protein names: 23S rRNA mA1618 methyltransferase; rRNA adenine N-6-methyltransferase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNKALLAHFYAVKHWDIPDGFLCPPVPGRADYIHHLADLLAGDSGEVPKDATILDIGTGANLIYPLIGAHEYGWRFTGSE
INPQAFASAQAIINGNPGLTRQIRLRRQKESQAIFHGVIHKNETYDATLCNPPFHDSAESARAGGERKRRNLGLGAESGL
NFGGQQQELWCEGGEVAFISQMIRESQAFARQVKWFTSLVSRGDNLPPLYRLLTEVGAVKVVKKEMAQGQKQSRFIAWSF
MDDAKRRRPF

Sequences:

>Translated_250_residues
MNKALLAHFYAVKHWDIPDGFLCPPVPGRADYIHHLADLLAGDSGEVPKDATILDIGTGANLIYPLIGAHEYGWRFTGSE
INPQAFASAQAIINGNPGLTRQIRLRRQKESQAIFHGVIHKNETYDATLCNPPFHDSAESARAGGERKRRNLGLGAESGL
NFGGQQQELWCEGGEVAFISQMIRESQAFARQVKWFTSLVSRGDNLPPLYRLLTEVGAVKVVKKEMAQGQKQSRFIAWSF
MDDAKRRRPF
>Mature_250_residues
MNKALLAHFYAVKHWDIPDGFLCPPVPGRADYIHHLADLLAGDSGEVPKDATILDIGTGANLIYPLIGAHEYGWRFTGSE
INPQAFASAQAIINGNPGLTRQIRLRRQKESQAIFHGVIHKNETYDATLCNPPFHDSAESARAGGERKRRNLGLGAESGL
NFGGQQQELWCEGGEVAFISQMIRESQAFARQVKWFTSLVSRGDNLPPLYRLLTEVGAVKVVKKEMAQGQKQSRFIAWSF
MDDAKRRRPF

Specific function: Specifically methylates the adenine in position 1618 of 23S rRNA [H]

COG id: COG3129

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. METT10D/rlmF family [H]

Homologues:

Organism=Homo sapiens, GI122114654, Length=241, Percent_Identity=31.9502074688797, Blast_Score=124, Evalue=5e-29,
Organism=Escherichia coli, GI87081786, Length=248, Percent_Identity=80.241935483871, Blast_Score=428, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI32564931, Length=240, Percent_Identity=27.0833333333333, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32564933, Length=240, Percent_Identity=24.1666666666667, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281363415, Length=246, Percent_Identity=30.4878048780488, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI19922302, Length=246, Percent_Identity=30.4878048780488, Blast_Score=100, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016909
- InterPro:   IPR010286 [H]

Pfam domain/function: PF05971 Methyltransf_10 [H]

EC number: =2.1.1.181 [H]

Molecular weight: Translated: 27831; Mature: 27831

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKALLAHFYAVKHWDIPDGFLCPPVPGRADYIHHLADLLAGDSGEVPKDATILDIGTGA
CCCHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
NLIYPLIGAHEYGWRFTGSEINPQAFASAQAIINGNPGLTRQIRLRRQKESQAIFHGVIH
HHHHHHHCCCCCCCEEECCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHC
KNETYDATLCNPPFHDSAESARAGGERKRRNLGLGAESGLNFGGQQQELWCEGGEVAFIS
CCCCCCEEECCCCCCCCHHHHHCCCHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCHHHHH
QMIRESQAFARQVKWFTSLVSRGDNLPPLYRLLTEVGAVKVVKKEMAQGQKQSRFIAWSF
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCEEEEEEH
MDDAKRRRPF
HHHHHHCCCC
>Mature Secondary Structure
MNKALLAHFYAVKHWDIPDGFLCPPVPGRADYIHHLADLLAGDSGEVPKDATILDIGTGA
CCCHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
NLIYPLIGAHEYGWRFTGSEINPQAFASAQAIINGNPGLTRQIRLRRQKESQAIFHGVIH
HHHHHHHCCCCCCCEEECCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHC
KNETYDATLCNPPFHDSAESARAGGERKRRNLGLGAESGLNFGGQQQELWCEGGEVAFIS
CCCCCCEEECCCCCCCCHHHHHCCCHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCHHHHH
QMIRESQAFARQVKWFTSLVSRGDNLPPLYRLLTEVGAVKVVKKEMAQGQKQSRFIAWSF
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCEEEEEEH
MDDAKRRRPF
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA