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The map label for this gene is basS [H]

Identifier: 238893827

GI number: 238893827

Start: 1700354

End: 1701451

Strand: Reverse

Name: basS [H]

Synonym: KP1_1759

Alternate gene names: 238893827

Gene position: 1701451-1700354 (Counterclockwise)

Preceding gene: 238893828

Following gene: 238893825

Centisome position: 32.42

GC content: 61.93

Gene sequence:

>1098_bases
ATGGCTCTGTTTGCAACTGAAACCTGGACCATGCGCCACCGGCTGCTGCTGACCATCGGCGCCATCCTGGTGGTCTGCCA
GCTGATAAGCGTCTTCTGGCTATGGCATGAGAGCAAAGAGCAGATCCAGCTGCTGGTGGCCAGCGCTATCGAAGGGCACA
ACAACCAGAAACATGTGGAGCATGAGGTACGGGAAGCGGTTGCCAGCCTGCTGGTGCCGAGCCTGCTGATCGTTGGCCTG
GCGCTGTATATCAGCATGCTGGCGGTGCGCAAGATCACCCGCCCGCTTTCACGTCTGCAAAGCGAACTGGAGAACCGCAC
GCCGGACAACCTCACCCCTATCGTACTCAGCGAATCGGTGCCCGAAGTCACGGCGGTGACCACCGCCCTGAATCAGTTGG
TTTCCCGCCTCAATCTGACCCTCGACCGCGAGCGGCTGTTTACCGCCGACGTGGCGCATGAGCTACGCACCCCGCTGGCC
GGGCTGCGGCTGCACCTTGAGCTGCTGGCGAAAGTGCATGGCATGGGCGTCGACCCGCTGATCCAGCGTCTCGATCAGAT
GACCACCAGCATTTCCCAGCTGCTGCAGCTGGCGCGCGTCGGCCAGTCCTTCTCCGCCGGCAGCTACCAGCAGGTGCTGT
TGCTGGATGACGTGGTAAAACCCCTGCAGGACGAACTGGAGGCTATGCTGGCGCAGCGTCAGCAGCGGCTGCTGCTGACG
GATATCGAAAACGAGGCCGTCGTCTCTGGCGATGCGACGTTAATCCGCGTGATCCTGCGCAATCTGGTGGAGAATGCTCA
CCGCTACAGCCCTGAAGGGTCGACGATCCGCGTGTCGGTGAAAGCGGGCCTGATGCCGGTGATGGCGGTGGAAGATGAAG
GGCCGGGGATCGATGAGGCGAAAAGCGGCGAACTCAGTAAAGCCTTCGTGCGCATGGACAGTCGCTACGGCGGCATTGGC
CTCGGACTGAGCATCGTCACGCGCATCGCTCAGCTGCATGACGCCCAGTTTTTTTTGCATAACCGACAGCCAGGGCCAGG
GGTCCGCGCGTGGGTGCTATTCCCGCAGCGCGGGGGTCAGAACGTCAGCACCCATTGA

Upstream 100 bases:

>100_bases
GCATATTCACAACCTACGCGAAAAGATTGGCAAATCGCGGATCCGCACCGTCCGGGGCTTTGGCTATATGCTGGCTAACA
ACATCGACACGGAATAGACC

Downstream 100 bases:

>100_bases
TGGAAGAAGGCAACAATAATGACCAGGGCGGTGGCGACCGCCAGATATTCACGGAAGTTAATTTTTTGCATGGGCGCTAT
CCTCATCAGGTTGAAGATAG

Product: sensor protein BasS/PmrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MALFATETWTMRHRLLLTIGAILVVCQLISVFWLWHESKEQIQLLVASAIEGHNNQKHVEHEVREAVASLLVPSLLIVGL
ALYISMLAVRKITRPLSRLQSELENRTPDNLTPIVLSESVPEVTAVTTALNQLVSRLNLTLDRERLFTADVAHELRTPLA
GLRLHLELLAKVHGMGVDPLIQRLDQMTTSISQLLQLARVGQSFSAGSYQQVLLLDDVVKPLQDELEAMLAQRQQRLLLT
DIENEAVVSGDATLIRVILRNLVENAHRYSPEGSTIRVSVKAGLMPVMAVEDEGPGIDEAKSGELSKAFVRMDSRYGGIG
LGLSIVTRIAQLHDAQFFLHNRQPGPGVRAWVLFPQRGGQNVSTH

Sequences:

>Translated_365_residues
MALFATETWTMRHRLLLTIGAILVVCQLISVFWLWHESKEQIQLLVASAIEGHNNQKHVEHEVREAVASLLVPSLLIVGL
ALYISMLAVRKITRPLSRLQSELENRTPDNLTPIVLSESVPEVTAVTTALNQLVSRLNLTLDRERLFTADVAHELRTPLA
GLRLHLELLAKVHGMGVDPLIQRLDQMTTSISQLLQLARVGQSFSAGSYQQVLLLDDVVKPLQDELEAMLAQRQQRLLLT
DIENEAVVSGDATLIRVILRNLVENAHRYSPEGSTIRVSVKAGLMPVMAVEDEGPGIDEAKSGELSKAFVRMDSRYGGIG
LGLSIVTRIAQLHDAQFFLHNRQPGPGVRAWVLFPQRGGQNVSTH
>Mature_364_residues
ALFATETWTMRHRLLLTIGAILVVCQLISVFWLWHESKEQIQLLVASAIEGHNNQKHVEHEVREAVASLLVPSLLIVGLA
LYISMLAVRKITRPLSRLQSELENRTPDNLTPIVLSESVPEVTAVTTALNQLVSRLNLTLDRERLFTADVAHELRTPLAG
LRLHLELLAKVHGMGVDPLIQRLDQMTTSISQLLQLARVGQSFSAGSYQQVLLLDDVVKPLQDELEAMLAQRQQRLLLTD
IENEAVVSGDATLIRVILRNLVENAHRYSPEGSTIRVSVKAGLMPVMAVEDEGPGIDEAKSGELSKAFVRMDSRYGGIGL
GLSIVTRIAQLHDAQFFLHNRQPGPGVRAWVLFPQRGGQNVSTH

Specific function: Member of the two-component regulatory system BasS/BasR Autophosphorylates and activates BasR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790551, Length=343, Percent_Identity=66.4723032069971, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1789403, Length=303, Percent_Identity=31.6831683168317, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786783, Length=310, Percent_Identity=28.3870967741935, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789808, Length=291, Percent_Identity=28.5223367697594, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=30.1310043668122, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI87081816, Length=196, Percent_Identity=34.1836734693878, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787894, Length=212, Percent_Identity=33.0188679245283, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=27.4131274131274, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788279, Length=301, Percent_Identity=27.2425249169435, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790346, Length=257, Percent_Identity=27.6264591439689, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40452; Mature: 40320

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALFATETWTMRHRLLLTIGAILVVCQLISVFWLWHESKEQIQLLVASAIEGHNNQKHVE
CCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHH
HEVREAVASLLVPSLLIVGLALYISMLAVRKITRPLSRLQSELENRTPDNLTPIVLSESV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCC
PEVTAVTTALNQLVSRLNLTLDRERLFTADVAHELRTPLAGLRLHLELLAKVHGMGVDPL
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHH
IQRLDQMTTSISQLLQLARVGQSFSAGSYQQVLLLDDVVKPLQDELEAMLAQRQQRLLLT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
DIENEAVVSGDATLIRVILRNLVENAHRYSPEGSTIRVSVKAGLMPVMAVEDEGPGIDEA
ECCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCCCCCCC
KSGELSKAFVRMDSRYGGIGLGLSIVTRIAQLHDAQFFLHNRQPGPGVRAWVLFPQRGGQ
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCC
NVSTH
CCCCC
>Mature Secondary Structure 
ALFATETWTMRHRLLLTIGAILVVCQLISVFWLWHESKEQIQLLVASAIEGHNNQKHVE
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHH
HEVREAVASLLVPSLLIVGLALYISMLAVRKITRPLSRLQSELENRTPDNLTPIVLSESV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCC
PEVTAVTTALNQLVSRLNLTLDRERLFTADVAHELRTPLAGLRLHLELLAKVHGMGVDPL
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHH
IQRLDQMTTSISQLLQLARVGQSFSAGSYQQVLLLDDVVKPLQDELEAMLAQRQQRLLLT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
DIENEAVVSGDATLIRVILRNLVENAHRYSPEGSTIRVSVKAGLMPVMAVEDEGPGIDEA
ECCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCCCCCCC
KSGELSKAFVRMDSRYGGIGLGLSIVTRIAQLHDAQFFLHNRQPGPGVRAWVLFPQRGGQ
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCC
NVSTH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 7610040; 9278503 [H]