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The map label for this gene is citA [H]

Identifier: 238893734

GI number: 238893734

Start: 1601077

End: 1601592

Strand: Reverse

Name: citA [H]

Synonym: KP1_1658

Alternate gene names: 238893734

Gene position: 1601592-1601077 (Counterclockwise)

Preceding gene: 238893735

Following gene: 238893730

Centisome position: 30.52

GC content: 62.79

Gene sequence:

>516_bases
ATGGGCGCCTCTGCCGCCCTTCCCGCTCACGCCCCTGGGGTGACTTTCCTCATCCCCGCTTTGTCCGGAGAGTTGATATG
GAACTTCGCCAGCGGGGCGATCTCTGACCGGATCGGTCGTCGTCCGGTGCTGATGGGCATTACCGTGCTGGCGCTGCTCA
CCACCTGGCCGGTGATGCACTGGCTCACCGTCGCGCCCGATTTCACCCGTATGACGCTGGTCCTGCTATGGTTCTCGTTC
TTCTTTGGCATGTATAACGGCGCGATGGTCGCGGCGCTTACCGAAGTTATGCCGGTATACGTCCGCACCGTGGGCTTTTC
GCTGGCCTTTAGTCTCGCTACTGCCATTTTCGGCGGCCTGACGCCAGCTATTTCCACCGCCCTGGTCGAGCTCAGCGGCG
ATAAAAGCGCGCCGGGCTGGTGGCTAATGTGCGCCGCGCAGTGCGGATTCATTGCCACCGCGCTACTGTTCGTGCGGCTG
AGCCGCGGCTATCAGCCGGCGGAGAGTCAGCGCTAA

Upstream 100 bases:

>100_bases
GAAGGGGATTGCCGCGAGGACGAACACGCCCACGACGCGGTGGAAAAATAATTCCCCGTTTCGCTGAGACTGAAAAGCCA
ACCTGCCGGTTGGCTTTTTT

Downstream 100 bases:

>100_bases
AAAAACAAACGGGCGGAGATATGCCCCGCCCGTTTGCCGCTGCCGTCTGATTTAATGGGTCGTATTATTGCTGCGGATCT
CCTTCCAGATCTGATCGCAG

Product: putative citrate utilization protein A

Products: betaine [Cytoplasm]; Proton [Cytoplasm]; L-proline [Cytoplasm] [C]

Alternate protein names: Citrate carrier protein; Citrate transporter; Citrate utilization determinant; Citrate utilization protein A [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MGASAALPAHAPGVTFLIPALSGELIWNFASGAISDRIGRRPVLMGITVLALLTTWPVMHWLTVAPDFTRMTLVLLWFSF
FFGMYNGAMVAALTEVMPVYVRTVGFSLAFSLATAIFGGLTPAISTALVELSGDKSAPGWWLMCAAQCGFIATALLFVRL
SRGYQPAESQR

Sequences:

>Translated_171_residues
MGASAALPAHAPGVTFLIPALSGELIWNFASGAISDRIGRRPVLMGITVLALLTTWPVMHWLTVAPDFTRMTLVLLWFSF
FFGMYNGAMVAALTEVMPVYVRTVGFSLAFSLATAIFGGLTPAISTALVELSGDKSAPGWWLMCAAQCGFIATALLFVRL
SRGYQPAESQR
>Mature_170_residues
GASAALPAHAPGVTFLIPALSGELIWNFASGAISDRIGRRPVLMGITVLALLTTWPVMHWLTVAPDFTRMTLVLLWFSFF
FGMYNGAMVAALTEVMPVYVRTVGFSLAFSLATAIFGGLTPAISTALVELSGDKSAPGWWLMCAAQCGFIATALLFVRLS
RGYQPAESQR

Specific function: Uptake of citrate across the boundary membrane with the concomitant transport of protons into the cell (symport system) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 18349; Mature: 18218

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGASAALPAHAPGVTFLIPALSGELIWNFASGAISDRIGRRPVLMGITVLALLTTWPVMH
CCCCCCCCCCCCCCEEEEEHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
WLTVAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVYVRTVGFSLAFSLATAIFGGL
HHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
TPAISTALVELSGDKSAPGWWLMCAAQCGFIATALLFVRLSRGYQPAESQR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GASAALPAHAPGVTFLIPALSGELIWNFASGAISDRIGRRPVLMGITVLALLTTWPVMH
CCCCCCCCCCCCCEEEEEHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
WLTVAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVYVRTVGFSLAFSLATAIFGGL
HHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
TPAISTALVELSGDKSAPGWWLMCAAQCGFIATALLFVRLSRGYQPAESQR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: betaine [Periplasm]; Proton [Periplasm]; L-proline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + betaine [Periplasm] = Proton [Cytoplasm] + betaine [Cytoplasm] Proton [Periplasm] + L-proline [Periplasm] = Proton [Cytoplasm] + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]