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The map label for this gene is nagD [H]

Identifier: 238893724

GI number: 238893724

Start: 1590531

End: 1591283

Strand: Reverse

Name: nagD [H]

Synonym: KP1_1646

Alternate gene names: 238893724

Gene position: 1591283-1590531 (Counterclockwise)

Preceding gene: 238893725

Following gene: 238893723

Centisome position: 30.32

GC content: 56.71

Gene sequence:

>753_bases
ATGACCATTCAAAACATAATTTGTGATATTGACGGCGTACTGATGCACGATAACGTCGCCGTTCCCGGCGCAGCCGAGTT
TATCAAGCGCATCCTCGATAAAGGCATGCCGCTGGTAATGCTGACCAACTACCCGTCGCAAACCGGCCAGGATCTGGCGA
ACCGTTTCGCCACCGCTGGAATTGATGTTCCGGATAGCGCCTTTTACACCTCAGCGATGGCCACCGCCGATTTTCTGCGT
CGCCAGGAAGGCAAAAAAGCCTACGTGGTGGGAGAAGGGGCGCTGATCCACGAGCTGTACAAAGCCGGCTTTACCATTAC
CGATGTGAACCCGGATTTTGTCATCGTCGGGGAAACTCGTTCCTTTAACTGGGAAATGATGCATAAGGCCGCCTTCTTCG
TCGCCAACGGCGCCCGCTTCATTGCCACTAACCCGGATACGCACGGTCGCGGCTTCTACCCTGCCTGCGGCGCGCTGTGC
GCCGGGATCGAGAAGATCTCCGGCCGTAAGCCGTTTTACGTCGGCAAACCCAGCCCGTGGATCATCCGTTCAGCGCTGAA
TAAAATGCAGGCTCACTCCGAGCAGACGGTGATTGTCGGCGATAACCTGCGCACCGATATACTGGCCGGTTTCCAGGCAG
GGCTGGAGACTATTCTGGTGCTCTCCGGCGTCTCCACCCTCGACGACATCGACAGCATGCCGTTCCGCCCGTCGTGGATT
TACCCTTCCGTCGCGGAAATCGATATTTTCTGA

Upstream 100 bases:

>100_bases
AGCGCGTCACCTTGATACGGACGGGCCTCGCCCGTCAGAGGTGTGAAACCTCATCGATGACGCGTATAGTTTCGTCTTTG
TTAATGATTCTGGACCCACC

Downstream 100 bases:

>100_bases
TGCCAACCACGTCGCAGGACGTGGTTTTTCATTTCTAGCGCCCATCAGAATTACCCCATCTAATAAAAACGGCCTATAAA
TACGAATTCCTCAATAAAGC

Product: UMP phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTIQNIICDIDGVLMHDNVAVPGAAEFIKRILDKGMPLVMLTNYPSQTGQDLANRFATAGIDVPDSAFYTSAMATADFLR
RQEGKKAYVVGEGALIHELYKAGFTITDVNPDFVIVGETRSFNWEMMHKAAFFVANGARFIATNPDTHGRGFYPACGALC
AGIEKISGRKPFYVGKPSPWIIRSALNKMQAHSEQTVIVGDNLRTDILAGFQAGLETILVLSGVSTLDDIDSMPFRPSWI
YPSVAEIDIF

Sequences:

>Translated_250_residues
MTIQNIICDIDGVLMHDNVAVPGAAEFIKRILDKGMPLVMLTNYPSQTGQDLANRFATAGIDVPDSAFYTSAMATADFLR
RQEGKKAYVVGEGALIHELYKAGFTITDVNPDFVIVGETRSFNWEMMHKAAFFVANGARFIATNPDTHGRGFYPACGALC
AGIEKISGRKPFYVGKPSPWIIRSALNKMQAHSEQTVIVGDNLRTDILAGFQAGLETILVLSGVSTLDDIDSMPFRPSWI
YPSVAEIDIF
>Mature_249_residues
TIQNIICDIDGVLMHDNVAVPGAAEFIKRILDKGMPLVMLTNYPSQTGQDLANRFATAGIDVPDSAFYTSAMATADFLRR
QEGKKAYVVGEGALIHELYKAGFTITDVNPDFVIVGETRSFNWEMMHKAAFFVANGARFIATNPDTHGRGFYPACGALCA
GIEKISGRKPFYVGKPSPWIIRSALNKMQAHSEQTVIVGDNLRTDILAGFQAGLETILVLSGVSTLDDIDSMPFRPSWIY
PSVAEIDIF

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI10092677, Length=252, Percent_Identity=29.7619047619048, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI108796653, Length=265, Percent_Identity=30.5660377358491, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI14149777, Length=247, Percent_Identity=25.1012145748988, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1786890, Length=249, Percent_Identity=93.1726907630522, Blast_Score=495, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI17558880, Length=263, Percent_Identity=27.3764258555133, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562458, Length=286, Percent_Identity=26.5734265734266, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17560956, Length=263, Percent_Identity=27.3764258555133, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71984613, Length=269, Percent_Identity=28.2527881040892, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562356, Length=233, Percent_Identity=24.0343347639485, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI193210059, Length=258, Percent_Identity=25.1937984496124, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319965, Length=231, Percent_Identity=26.8398268398268, Blast_Score=81, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24666141, Length=253, Percent_Identity=27.6679841897233, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24656326, Length=258, Percent_Identity=27.5193798449612, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI22026920, Length=243, Percent_Identity=27.5720164609054, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24666137, Length=291, Percent_Identity=27.1477663230241, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24656330, Length=275, Percent_Identity=27.6363636363636, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI19920940, Length=254, Percent_Identity=25.1968503937008, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 27331; Mature: 27199

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQNIICDIDGVLMHDNVAVPGAAEFIKRILDKGMPLVMLTNYPSQTGQDLANRFATAG
CCHHHEEECCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCC
IDVPDSAFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKAGFTITDVNPDFVIVGETR
CCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCEEEECCCCEEEEECCC
SFNWEMMHKAAFFVANGARFIATNPDTHGRGFYPACGALCAGIEKISGRKPFYVGKPSPW
CCCHHHHHHEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCH
IIRSALNKMQAHSEQTVIVGDNLRTDILAGFQAGLETILVLSGVSTLDDIDSMPFRPSWI
HHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCC
YPSVAEIDIF
CCCCEEEECC
>Mature Secondary Structure 
TIQNIICDIDGVLMHDNVAVPGAAEFIKRILDKGMPLVMLTNYPSQTGQDLANRFATAG
CHHHEEECCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCC
IDVPDSAFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKAGFTITDVNPDFVIVGETR
CCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCEEEECCCCEEEEECCC
SFNWEMMHKAAFFVANGARFIATNPDTHGRGFYPACGALCAGIEKISGRKPFYVGKPSPW
CCCHHHHHHEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCH
IIRSALNKMQAHSEQTVIVGDNLRTDILAGFQAGLETILVLSGVSTLDDIDSMPFRPSWI
HHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCC
YPSVAEIDIF
CCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]