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The map label for this gene is gltK [H]

Identifier: 238893714

GI number: 238893714

Start: 1577496

End: 1578170

Strand: Reverse

Name: gltK [H]

Synonym: KP1_1636

Alternate gene names: 238893714

Gene position: 1578170-1577496 (Counterclockwise)

Preceding gene: 238893715

Following gene: 238893713

Centisome position: 30.07

GC content: 57.78

Gene sequence:

>675_bases
ATGTACGATTTTGACTGGAGTTCGATCGTTCCCTCCATGCCCTATCTGCTGGCAGGGCTGGTGATCACCCTTAAGATTAC
GGTGATCGCCATCGTGGTCGGCATCGTCTGGGGCACTCTGCTGGCGGTTATGCGCCTGTCCAGCTTTATGCCGCTGGCCT
GGTTTGCTAAATCCTACGTCAACGTATTCCGCTCAATCCCACTGGTGATGGTCCTGCTGTGGTTCTACCTGATTGTCCCG
GGCTTCCTGCAGAACGTGCTGGGACTGTCGCCGAAAACGGATATTCGCCTGATCTCGGCGATGGTGGCGTTTTCGATGTT
CGAAGCCGCCTACTATTCAGAGATTATCCGCGCCGGCATTCAGAGCATCTCCCGCGGCCAGTCCAGCGCCGCGCTGGCGT
TGGGGATGACCCACTGGCAGTCAATGCGGCTGGTGATCCTGCCGCAGGCCTTCCGCGCCATGGTGCCGCTGCTGCTAACC
CAGGGGATCGTCCTGTTCCAGGATACCTCGCTGGTGTATGTATTGAGTCTCGCCGACTTCTTCCGTACCGCCTCCACCAT
TGGCGAGCGTGACGGAACCCAGGTCGAAATGATCCTGTTCGCGGGCGGCGTCTATTTTGTGATTAGCCTCAGCGCCTCGC
TGTTGGTCAGCTGGTTGAAGAAAAGGACTGTGTAA

Upstream 100 bases:

>100_bases
CCATCACCCTGGCCTATGTTTTCATCAACGCGGTGATTATGCTGATTATGTATGTGGTCGAGCGTAAGGTTCGCCTGCCT
GGCAATATGGGAGGCAAATA

Downstream 100 bases:

>100_bases
TGATTACCCTGAAAAACGTTTCAAAATGGTATGGTCACTTTCAGGTGCTGACCGATTGCTCCACGGAAGTGAAAAAAGGC
GAAGTCGTGGTGGTCTGCGG

Product: glutamate/aspartate transport system permease component

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MYDFDWSSIVPSMPYLLAGLVITLKITVIAIVVGIVWGTLLAVMRLSSFMPLAWFAKSYVNVFRSIPLVMVLLWFYLIVP
GFLQNVLGLSPKTDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLT
QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGGVYFVISLSASLLVSWLKKRTV

Sequences:

>Translated_224_residues
MYDFDWSSIVPSMPYLLAGLVITLKITVIAIVVGIVWGTLLAVMRLSSFMPLAWFAKSYVNVFRSIPLVMVLLWFYLIVP
GFLQNVLGLSPKTDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLT
QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGGVYFVISLSASLLVSWLKKRTV
>Mature_224_residues
MYDFDWSSIVPSMPYLLAGLVITLKITVIAIVVGIVWGTLLAVMRLSSFMPLAWFAKSYVNVFRSIPLVMVLLWFYLIVP
GFLQNVLGLSPKTDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLT
QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGGVYFVISLSASLLVSWLKKRTV

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=223, Percent_Identity=92.3766816143498, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1788226, Length=214, Percent_Identity=36.4485981308411, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI87082239, Length=208, Percent_Identity=32.6923076923077, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787030, Length=224, Percent_Identity=32.5892857142857, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786874, Length=190, Percent_Identity=27.8947368421053, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1787087, Length=205, Percent_Identity=26.3414634146341, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI48994930, Length=128, Percent_Identity=35.15625, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788645, Length=206, Percent_Identity=25.7281553398058, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788646, Length=211, Percent_Identity=23.696682464455, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787086, Length=216, Percent_Identity=24.537037037037, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24879; Mature: 24879

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDFDWSSIVPSMPYLLAGLVITLKITVIAIVVGIVWGTLLAVMRLSSFMPLAWFAKSYV
CCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
NVFRSIPLVMVLLWFYLIVPGFLQNVLGLSPKTDIRLISAMVAFSMFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLTQGIVLFQDTSLVYVLSLADF
HHHHCCCCHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHH
FRTASTIGERDGTQVEMILFAGGVYFVISLSASLLVSWLKKRTV
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYDFDWSSIVPSMPYLLAGLVITLKITVIAIVVGIVWGTLLAVMRLSSFMPLAWFAKSYV
CCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
NVFRSIPLVMVLLWFYLIVPGFLQNVLGLSPKTDIRLISAMVAFSMFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLTQGIVLFQDTSLVYVLSLADF
HHHHCCCCHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHH
FRTASTIGERDGTQVEMILFAGGVYFVISLSASLLVSWLKKRTV
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]