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The map label for this gene is lipB [H]

Identifier: 238893697

GI number: 238893697

Start: 1558875

End: 1559519

Strand: Reverse

Name: lipB [H]

Synonym: KP1_1617

Alternate gene names: 238893697

Gene position: 1559519-1558875 (Counterclockwise)

Preceding gene: 238893698

Following gene: 238893696

Centisome position: 29.71

GC content: 58.91

Gene sequence:

>645_bases
TTGCAGCACAATAAAATTCTTATCCGGCAGCTTGGCCTGCAACCTTACGAACCCGTCTCGCAGGCGATGCATGAATTTAC
CGACGCCCGTGATGAAGATACCCTCGACGAGATCTGGCTGGTGGAACATCACCCCGTATTCACCCAGGGTCAGGCCGGCA
AAGCGGAACACGTGCTGGTGCCCGGCGATATTCCGGTGATCCAGAGCGATCGCGGCGGCCAGGTCACCTATCACGGTCCG
GGACAGCAGGTGATGTACGTCCTGTTGGACCTCAAGCGCCGTAAGCTGGGCGTGCGGGAGCTGGTGACGCTGCTGGAGCA
AACGGTCGTCAATACCCTGGCTGAATATAGTATCGAGTCGCACCCCCGCGCCGACGCCCCTGGCGTCTATGTCGGCGAAC
GCAAAATCTGCTCTCTGGGATTGCGGATCCGTAAAGGTTGTTCTTTCCACGGTCTGGCGCTTAATATCGCCATGGATCTC
ACACCGTTTCTGCGTATCAACCCCTGCGGCTATGCCGGTATGGAGATGACGCAAATGCGCCAGTGGCAGCCTGCAGCCTC
CCCGGAGACGGTCGCTCCGCGGCTGGTCGCCAATCTGCTGGCGCTGCTAAATCATCCACCGCACGAATATCTTCCCCGGG
ATTAA

Upstream 100 bases:

>100_bases
TTCCCTGACCCGGCCGCCGTGCCGGGTCTTCTCATTCCCTTCTGCACGGCTGTGATATACTCCCCAACCTGAATTCTCTC
TTCCCGGCGGAGATGTTGTT

Downstream 100 bases:

>100_bases
GCGGCAGGCCAACGTCCCGCTGTCAGCGGGGCGCTAAACGAGTAACACGTTATTTTTGCAATCAATTGTCACGCACGGCA
ACGCGGTGGGCCGCTATACT

Product: lipoyltransferase

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MQHNKILIRQLGLQPYEPVSQAMHEFTDARDEDTLDEIWLVEHHPVFTQGQAGKAEHVLVPGDIPVIQSDRGGQVTYHGP
GQQVMYVLLDLKRRKLGVRELVTLLEQTVVNTLAEYSIESHPRADAPGVYVGERKICSLGLRIRKGCSFHGLALNIAMDL
TPFLRINPCGYAGMEMTQMRQWQPAASPETVAPRLVANLLALLNHPPHEYLPRD

Sequences:

>Translated_214_residues
MQHNKILIRQLGLQPYEPVSQAMHEFTDARDEDTLDEIWLVEHHPVFTQGQAGKAEHVLVPGDIPVIQSDRGGQVTYHGP
GQQVMYVLLDLKRRKLGVRELVTLLEQTVVNTLAEYSIESHPRADAPGVYVGERKICSLGLRIRKGCSFHGLALNIAMDL
TPFLRINPCGYAGMEMTQMRQWQPAASPETVAPRLVANLLALLNHPPHEYLPRD
>Mature_214_residues
MQHNKILIRQLGLQPYEPVSQAMHEFTDARDEDTLDEIWLVEHHPVFTQGQAGKAEHVLVPGDIPVIQSDRGGQVTYHGP
GQQVMYVLLDLKRRKLGVRELVTLLEQTVVNTLAEYSIESHPRADAPGVYVGERKICSLGLRIRKGCSFHGLALNIAMDL
TPFLRINPCGYAGMEMTQMRQWQPAASPETVAPRLVANLLALLNHPPHEYLPRD

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG0321

COG function: function code H; Lipoate-protein ligase B

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipB family [H]

Homologues:

Organism=Homo sapiens, GI221554520, Length=129, Percent_Identity=40.3100775193798, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI87081767, Length=211, Percent_Identity=81.9905213270142, Blast_Score=376, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6323268, Length=196, Percent_Identity=30.1020408163265, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355483, Length=147, Percent_Identity=34.6938775510204, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 24026; Mature: 24026

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01313 LIPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHNKILIRQLGLQPYEPVSQAMHEFTDARDEDTLDEIWLVEHHPVFTQGQAGKAEHVLV
CCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHEEEEECCCCEECCCCCCCCEEEE
PGDIPVIQSDRGGQVTYHGPGQQVMYVLLDLKRRKLGVRELVTLLEQTVVNTLAEYSIES
CCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
HPRADAPGVYVGERKICSLGLRIRKGCSFHGLALNIAMDLTPFLRINPCGYAGMEMTQMR
CCCCCCCCEEECCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCCCCCCCHHHHHH
QWQPAASPETVAPRLVANLLALLNHPPHEYLPRD
HCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCC
>Mature Secondary Structure
MQHNKILIRQLGLQPYEPVSQAMHEFTDARDEDTLDEIWLVEHHPVFTQGQAGKAEHVLV
CCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHEEEEECCCCEECCCCCCCCEEEE
PGDIPVIQSDRGGQVTYHGPGQQVMYVLLDLKRRKLGVRELVTLLEQTVVNTLAEYSIES
CCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
HPRADAPGVYVGERKICSLGLRIRKGCSFHGLALNIAMDLTPFLRINPCGYAGMEMTQMR
CCCCCCCCEEECCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCCCCCCCHHHHHH
QWQPAASPETVAPRLVANLLALLNHPPHEYLPRD
HCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA