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The map label for this gene is mocR [H]

Identifier: 238893598

GI number: 238893598

Start: 1452205

End: 1453764

Strand: Reverse

Name: mocR [H]

Synonym: KP1_1511

Alternate gene names: 238893598

Gene position: 1453764-1452205 (Counterclockwise)

Preceding gene: 238893603

Following gene: 238893596

Centisome position: 27.7

GC content: 63.65

Gene sequence:

>1560_bases
ATGGGCCGCATCGCTGTGTCAGATGGCGGCAGGGTGGTATGGAATTTGCTGAGTGTAACGGGTGGTCGCAATGCGTTATT
GCCAGAGGAGCCCCGTATGATCCGTCACCTGTTACACGTTGATTTTCAGCCTGGCCGCGGTTTGCAGGAACAGGTGCGAG
AGACGCTGGTGAATGCCATTCTCAGCGGGATCTTCGCCGCCGACACCCCGCTGCCCTCCTGTCGCCAGCTGGCCAGCCAG
CTTCGCGTCTCGCGCAACACCACCGCGCTGGTGTTCGAAAGTCTGGTCAACGAGGGCTACCTGATTAGCCGCCCACGCAG
CGGTTACTACCTGCATCCCGACTATCATGAAGCTTCGCCTGCCGCCGTCGAGAGTGCACCGCAGCGCGAAGCCGCTGCAC
CACGCTGGGGCGACCGGCTGCAGATGACCCCCAGCCAGCAGGAGTCGATCCTCAAACCGGCGGGCTGGATGCACTACCGC
TACCCGTTTATCTACGGCCAGCCCGATACCCGGCAGTTCCCGCTGGCCACCTGGCGCTCGGCGGCGAACTGGCTGCACGG
CGGGGTGCGCGACCCGGCGTGGGTCATCGACCATATTGACCAGGATGTGCCGATGCTGATCGAGCAGATCCGCACCCGGG
TGCTGCCCAAGCGCGGCATTGTCGCCGCGCCGGATGAAATTCTCATCACCCTTGGTTCGCAAAATGCGCTCTACCTGCTG
ACCCGACTGCTGCTCTCTTCCACCACCCGCATTGGCGTCGAAAACCCCTGCTTCCGCGAAGCCATCAACACCTTTCTGCT
CGCCGACGCCGAGGTGGTGCCGCACCCGGTGGATGAAGAGGGGATCGTGCTTAATGAGCGTCCCTGCGATTACTACTATG
TCACACCAGGCCATCAGGTGCCCACCGGGGTGACCATGAGCAGTACGCGGCGTCGCCAGTTGCTGGAGCATGCCGCCCGC
CATGACGCGGTCATTATTGAAGATGATTATGACTCGGAGAGTAACTTTACCCTCAACCCGCTGCCGGCGCTGAAGGCCAG
CGATCGCAGCGGCCGGGTGGTGTATGTCAGCAGCCTGTCAAAAGCGCTGTCACCGGGGTTGCGGTTGGGGTTTATGGTCG
CCGACCCGGACCTGATCGACGAGGCGCGCGCCCTGCGCCGGCTGGTCTATCGCCATCCGCCGACCAACATTCAGTACCAG
ATGGCCCACTTCCTTGCCCAGGGCCATTATGAAACCCATCTGCGGCGCTACCACTATGACTCCGCCCAGCGCTGGGAGCG
TCTGCACGCCGCCCTGCAGCGCTATCTGCCGTCGTGTCGCGCGCTGGCGGGGAGCGAACATGCTAACGCCTTCTGGCTGC
AGACCCCGGCGCAGATCAACACCCAGCAGCTCACCTGGCGCGCCGCCCACGCCGGCGTGCTGATTGAGCCCGGGGCGCGC
CATTTTCTCAGCGCCGCGCCGCCGGATAACTATTTTCGCATGGGATTCCACGCCATTAACCCTGACGCCATCGCCCAGGG
GGTGGAGGTCCTGCGCGGCCAGCTGGAGCAGATGGGTTAG

Upstream 100 bases:

>100_bases
CGAAAAGGTTTCTGCAAAATAGTGGCCGGGGACGTTCCGGTCCACGGCGGCTGAATACGTTTTTAATGTGGGAGCGTTTT
TCAATTCCGTATAGAGCCAG

Downstream 100 bases:

>100_bases
CGGTATTGTTCATACTCAACGGCGTCGCGCACGCTGAGCAGCGCCGGGCGCAGGCTGTCGAAAGGCACCGATCCGAGCGC
AATGCGCAGCGCCTGCGGGA

Product: putative GntR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 518

Protein sequence:

>519_residues
MGRIAVSDGGRVVWNLLSVTGGRNALLPEEPRMIRHLLHVDFQPGRGLQEQVRETLVNAILSGIFAADTPLPSCRQLASQ
LRVSRNTTALVFESLVNEGYLISRPRSGYYLHPDYHEASPAAVESAPQREAAAPRWGDRLQMTPSQQESILKPAGWMHYR
YPFIYGQPDTRQFPLATWRSAANWLHGGVRDPAWVIDHIDQDVPMLIEQIRTRVLPKRGIVAAPDEILITLGSQNALYLL
TRLLLSSTTRIGVENPCFREAINTFLLADAEVVPHPVDEEGIVLNERPCDYYYVTPGHQVPTGVTMSSTRRRQLLEHAAR
HDAVIIEDDYDSESNFTLNPLPALKASDRSGRVVYVSSLSKALSPGLRLGFMVADPDLIDEARALRRLVYRHPPTNIQYQ
MAHFLAQGHYETHLRRYHYDSAQRWERLHAALQRYLPSCRALAGSEHANAFWLQTPAQINTQQLTWRAAHAGVLIEPGAR
HFLSAAPPDNYFRMGFHAINPDAIAQGVEVLRGQLEQMG

Sequences:

>Translated_519_residues
MGRIAVSDGGRVVWNLLSVTGGRNALLPEEPRMIRHLLHVDFQPGRGLQEQVRETLVNAILSGIFAADTPLPSCRQLASQ
LRVSRNTTALVFESLVNEGYLISRPRSGYYLHPDYHEASPAAVESAPQREAAAPRWGDRLQMTPSQQESILKPAGWMHYR
YPFIYGQPDTRQFPLATWRSAANWLHGGVRDPAWVIDHIDQDVPMLIEQIRTRVLPKRGIVAAPDEILITLGSQNALYLL
TRLLLSSTTRIGVENPCFREAINTFLLADAEVVPHPVDEEGIVLNERPCDYYYVTPGHQVPTGVTMSSTRRRQLLEHAAR
HDAVIIEDDYDSESNFTLNPLPALKASDRSGRVVYVSSLSKALSPGLRLGFMVADPDLIDEARALRRLVYRHPPTNIQYQ
MAHFLAQGHYETHLRRYHYDSAQRWERLHAALQRYLPSCRALAGSEHANAFWLQTPAQINTQQLTWRAAHAGVLIEPGAR
HFLSAAPPDNYFRMGFHAINPDAIAQGVEVLRGQLEQMG
>Mature_518_residues
GRIAVSDGGRVVWNLLSVTGGRNALLPEEPRMIRHLLHVDFQPGRGLQEQVRETLVNAILSGIFAADTPLPSCRQLASQL
RVSRNTTALVFESLVNEGYLISRPRSGYYLHPDYHEASPAAVESAPQREAAAPRWGDRLQMTPSQQESILKPAGWMHYRY
PFIYGQPDTRQFPLATWRSAANWLHGGVRDPAWVIDHIDQDVPMLIEQIRTRVLPKRGIVAAPDEILITLGSQNALYLLT
RLLLSSTTRIGVENPCFREAINTFLLADAEVVPHPVDEEGIVLNERPCDYYYVTPGHQVPTGVTMSSTRRRQLLEHAARH
DAVIIEDDYDSESNFTLNPLPALKASDRSGRVVYVSSLSKALSPGLRLGFMVADPDLIDEARALRRLVYRHPPTNIQYQM
AHFLAQGHYETHLRRYHYDSAQRWERLHAALQRYLPSCRALAGSEHANAFWLQTPAQINTQQLTWRAAHAGVLIEPGARH
FLSAAPPDNYFRMGFHAINPDAIAQGVEVLRGQLEQMG

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=308, Percent_Identity=23.0519480519481, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI33469970, Length=308, Percent_Identity=23.0519480519481, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1787710, Length=461, Percent_Identity=29.7180043383948, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790797, Length=415, Percent_Identity=25.7831325301205, Blast_Score=118, Evalue=1e-27,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 58359; Mature: 58228

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRIAVSDGGRVVWNLLSVTGGRNALLPEEPRMIRHLLHVDFQPGRGLQEQVRETLVNAI
CCEEEECCCCCEEHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LSGIFAADTPLPSCRQLASQLRVSRNTTALVFESLVNEGYLISRPRSGYYLHPDYHEASP
HHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCEECCCCCCCCC
AAVESAPQREAAAPRWGDRLQMTPSQQESILKPAGWMHYRYPFIYGQPDTRQFPLATWRS
HHHHCCCCHHCCCCCCCCCEECCCCHHHHHHCCCCCEEEECCEEECCCCCCCCCHHHHHH
AANWLHGGVRDPAWVIDHIDQDVPMLIEQIRTRVLPKRGIVAAPDEILITLGSQNALYLL
HHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEECCCEEEEEECCCCHHHHH
TRLLLSSTTRIGVENPCFREAINTFLLADAEVVPHPVDEEGIVLNERPCDYYYVTPGHQV
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCEEEECCCCCC
PTGVTMSSTRRRQLLEHAARHDAVIIEDDYDSESNFTLNPLPALKASDRSGRVVYVSSLS
CCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCEEEEEHHH
KALSPGLRLGFMVADPDLIDEARALRRLVYRHPPTNIQYQMAHFLAQGHYETHLRRYHYD
HHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHCCC
SAQRWERLHAALQRYLPSCRALAGSEHANAFWLQTPAQINTQQLTWRAAHAGVLIEPGAR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHEEEEECCCCEEECCCHH
HFLSAAPPDNYFRMGFHAINPDAIAQGVEVLRGQLEQMG
HHHCCCCCCCCEECCEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GRIAVSDGGRVVWNLLSVTGGRNALLPEEPRMIRHLLHVDFQPGRGLQEQVRETLVNAI
CEEEECCCCCEEHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LSGIFAADTPLPSCRQLASQLRVSRNTTALVFESLVNEGYLISRPRSGYYLHPDYHEASP
HHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCEECCCCCCCCC
AAVESAPQREAAAPRWGDRLQMTPSQQESILKPAGWMHYRYPFIYGQPDTRQFPLATWRS
HHHHCCCCHHCCCCCCCCCEECCCCHHHHHHCCCCCEEEECCEEECCCCCCCCCHHHHHH
AANWLHGGVRDPAWVIDHIDQDVPMLIEQIRTRVLPKRGIVAAPDEILITLGSQNALYLL
HHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEECCCEEEEEECCCCHHHHH
TRLLLSSTTRIGVENPCFREAINTFLLADAEVVPHPVDEEGIVLNERPCDYYYVTPGHQV
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCEEEECCCCCC
PTGVTMSSTRRRQLLEHAARHDAVIIEDDYDSESNFTLNPLPALKASDRSGRVVYVSSLS
CCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCEEEEEHHH
KALSPGLRLGFMVADPDLIDEARALRRLVYRHPPTNIQYQMAHFLAQGHYETHLRRYHYD
HHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHCCC
SAQRWERLHAALQRYLPSCRALAGSEHANAFWLQTPAQINTQQLTWRAAHAGVLIEPGAR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHEEEEECCCCEEECCCHH
HFLSAAPPDNYFRMGFHAINPDAIAQGVEVLRGQLEQMG
HHHCCCCCCCCEECCEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]