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The map label for this gene is mdtA [H]

Identifier: 238893586

GI number: 238893586

Start: 1436052

End: 1437131

Strand: Direct

Name: mdtA [H]

Synonym: KP1_1497

Alternate gene names: 238893586

Gene position: 1436052-1437131 (Clockwise)

Preceding gene: 238893585

Following gene: 238893587

Centisome position: 27.36

GC content: 66.2

Gene sequence:

>1080_bases
ATGATTAAAACCTTCCGCTTTGCTCTGCTGGCCTGCGGTCTGGTCGGCGGTGCCCTGACGGCGACCGCCGCGCCGGCGGT
GCCGGTCCGCGTCGCCACGGTTGAACTGGCTCCTCATGCTGAAGAACGCGCTATCCCCGGGCGGGTCGAGGCGATCCGCG
CCGTCGACATTCGTGCGCGCACCGAAGGGGTGATTGTTCAGCGCCACTTCCAGGACGGGCAGTATGTTACCGAAGGCGAC
CTGCTGTTTACCCTCGACGACGCGCAGCCCCGCGCGGCGCTGGCTCTGGCGCAGGCCGAGCTGAAAAGCGCCGAAGCCTC
ATTACGTCAGTCGCAGCAGTTGCTCACTCGCTACGAGCGGCTTATCAACAATCACTCCATCAGCCGCAACGACGTCGATA
CGGCCCGGATGCAGCGCGACGTCGCCGCCGCTGCCGTACAGCAGGCCAAAGCCCGCGTCGAGGCCCAGCAGATTGTGCTC
AGCTACACTCAGATTGCGGCGCCGGTGACCGGTCGCGTGGGCCATAGCGCCTTTCACGTCGGGACGCTGGTCAATTCGTC
CAGCGGCGTGCTGGTGGACATTGTGGAGTTGGATCCGGTGCGGGTCTCGTTCGCCCTCGACGAAGCCGCGTTTTTCAGCA
AAACCGGCCAGCACGCCGATATCCACGCTCTGAAGCAGGCGTGGCTGGCGCAGATTGAGGTTGATGGTAAACGGCGCGAC
GGGGTGTTGACCTCTATCGATAACCGGATCGACGCCCGCACCGGCAGCGTAGCGGTGCGGGCCGAGTTTGCCAATCCGCA
GCACCGTCTGCTGCCGGGCGGCAGCGTGACGATCCTGTTCCGTCCGCAGGAACTGCCGTCGCGAGTGATGGTCCCGGCCG
CCGCCGTGCAGCAGGATCCGCAGGGCTTTTTCAGCTGGGTGCTGAAGCCGGACCACACCGCCGGGCAGCGTCGTCTGACC
CTCGCGGGGCAGCAGGGGCAGCAGTTTGCGGTCGAGAAAGGGCTGCAGGCGGGCGAGCAGGTGATCACCGACGGCGCGCA
GCGGTTGCGCGAAGGCGCCGCGGTGCAGGTGCTGAACTAG

Upstream 100 bases:

>100_bases
GTGGAAATCGAGAAGCGTCTGACGCGCCGGTTCCGCAAAACGGCCTGAACAATCTCGCGCGCCTCGCTGCAGGCGCGCGT
TACTGTCGCAAGGATCCTCT

Downstream 100 bases:

>100_bases
CTAAGGAGAAGGGATGCTGACCTTTTTTATCCGTCGTCCGCGATTTGCCATGGTGATCGCGCTGCTGCTGACCTTTGTCG
GCGCGGTGTCGCTGAAGCTG

Product: putative secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MIKTFRFALLACGLVGGALTATAAPAVPVRVATVELAPHAEERAIPGRVEAIRAVDIRARTEGVIVQRHFQDGQYVTEGD
LLFTLDDAQPRAALALAQAELKSAEASLRQSQQLLTRYERLINNHSISRNDVDTARMQRDVAAAAVQQAKARVEAQQIVL
SYTQIAAPVTGRVGHSAFHVGTLVNSSSGVLVDIVELDPVRVSFALDEAAFFSKTGQHADIHALKQAWLAQIEVDGKRRD
GVLTSIDNRIDARTGSVAVRAEFANPQHRLLPGGSVTILFRPQELPSRVMVPAAAVQQDPQGFFSWVLKPDHTAGQRRLT
LAGQQGQQFAVEKGLQAGEQVITDGAQRLREGAAVQVLN

Sequences:

>Translated_359_residues
MIKTFRFALLACGLVGGALTATAAPAVPVRVATVELAPHAEERAIPGRVEAIRAVDIRARTEGVIVQRHFQDGQYVTEGD
LLFTLDDAQPRAALALAQAELKSAEASLRQSQQLLTRYERLINNHSISRNDVDTARMQRDVAAAAVQQAKARVEAQQIVL
SYTQIAAPVTGRVGHSAFHVGTLVNSSSGVLVDIVELDPVRVSFALDEAAFFSKTGQHADIHALKQAWLAQIEVDGKRRD
GVLTSIDNRIDARTGSVAVRAEFANPQHRLLPGGSVTILFRPQELPSRVMVPAAAVQQDPQGFFSWVLKPDHTAGQRRLT
LAGQQGQQFAVEKGLQAGEQVITDGAQRLREGAAVQVLN
>Mature_359_residues
MIKTFRFALLACGLVGGALTATAAPAVPVRVATVELAPHAEERAIPGRVEAIRAVDIRARTEGVIVQRHFQDGQYVTEGD
LLFTLDDAQPRAALALAQAELKSAEASLRQSQQLLTRYERLINNHSISRNDVDTARMQRDVAAAAVQQAKARVEAQQIVL
SYTQIAAPVTGRVGHSAFHVGTLVNSSSGVLVDIVELDPVRVSFALDEAAFFSKTGQHADIHALKQAWLAQIEVDGKRRD
GVLTSIDNRIDARTGSVAVRAEFANPQHRLLPGGSVTILFRPQELPSRVMVPAAAVQQDPQGFFSWVLKPDHTAGQRRLT
LAGQQGQQFAVEKGLQAGEQVITDGAQRLREGAAVQVLN

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=352, Percent_Identity=32.6704545454545, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1789929, Length=356, Percent_Identity=33.4269662921348, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786668, Length=336, Percent_Identity=32.4404761904762, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1789665, Length=377, Percent_Identity=30.5039787798408, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI87081951, Length=135, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38756; Mature: 38756

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTFRFALLACGLVGGALTATAAPAVPVRVATVELAPHAEERAIPGRVEAIRAVDIRAR
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHCCCCCHHHHEEEEEEEEC
TEGVIVQRHFQDGQYVTEGDLLFTLDDAQPRAALALAQAELKSAEASLRQSQQLLTRYER
CCCEEEEEECCCCCEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LINNHSISRNDVDTARMQRDVAAAAVQQAKARVEAQQIVLSYTQIAAPVTGRVGHSAFHV
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
GTLVNSSSGVLVDIVELDPVRVSFALDEAAFFSKTGQHADIHALKQAWLAQIEVDGKRRD
EEEEECCCCCEEEEEECCCEEEEEEEHHHHHHHCCCCCCHHHHHHHHHHEEEEECCCCCC
GVLTSIDNRIDARTGSVAVRAEFANPQHRLLPGGSVTILFRPQELPSRVMVPAAAVQQDP
CCEEHHCCCCCCCCCCEEEEEECCCCCCEECCCCCEEEEECCCCCCCHHCCCHHHHCCCC
QGFFSWVLKPDHTAGQRRLTLAGQQGQQFAVEKGLQAGEQVITDGAQRLREGAAVQVLN
CCHHHEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure
MIKTFRFALLACGLVGGALTATAAPAVPVRVATVELAPHAEERAIPGRVEAIRAVDIRAR
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHCCCCCHHHHEEEEEEEEC
TEGVIVQRHFQDGQYVTEGDLLFTLDDAQPRAALALAQAELKSAEASLRQSQQLLTRYER
CCCEEEEEECCCCCEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LINNHSISRNDVDTARMQRDVAAAAVQQAKARVEAQQIVLSYTQIAAPVTGRVGHSAFHV
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
GTLVNSSSGVLVDIVELDPVRVSFALDEAAFFSKTGQHADIHALKQAWLAQIEVDGKRRD
EEEEECCCCCEEEEEECCCEEEEEEEHHHHHHHCCCCCCHHHHHHHHHHEEEEECCCCCC
GVLTSIDNRIDARTGSVAVRAEFANPQHRLLPGGSVTILFRPQELPSRVMVPAAAVQQDP
CCEEHHCCCCCCCCCCEEEEEECCCCCCEECCCCCEEEEECCCCCCCHHCCCHHHHCCCC
QGFFSWVLKPDHTAGQRRLTLAGQQGQQFAVEKGLQAGEQVITDGAQRLREGAAVQVLN
CCHHHEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]