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The map label for this gene is 238893581

Identifier: 238893581

GI number: 238893581

Start: 1431020

End: 1432135

Strand: Direct

Name: 238893581

Synonym: KP1_1491

Alternate gene names: NA

Gene position: 1431020-1432135 (Clockwise)

Preceding gene: 238893571

Following gene: 238893582

Centisome position: 27.27

GC content: 60.04

Gene sequence:

>1116_bases
TTGTCTGGTCAGGATATGAACCGTGTCACTTTCAGCGTGGTCGCCATCATGTTACTCGCAGCAGCAACGACATTGCCGTT
TGTTCTTAATGCCGGTTTTGGTAAGGCGCCGCAGGGGGCACAGCTTAGCCAGGTGGAAGCGTCTCCCCACTACCGGGACG
GCCAGTTCCATAACCAGTTGCCCACGCCAGGGTTCACCGGGCAGAAAAATATGCTGGCGGCGTGGTGGGATTTCCTGATG
ACCAAACGGGAAAACGCCCGTCCCGCGCAACCGCTGCCGCTGGTGAAGACCGATCTGGCGACGCTGCCCCTCGGGCAGGA
CGTGATGGTCTGGCTCGGCCACTCCTCCTGGTACCTGCAGCTGGCGGGAAAACGCATCCTGATCGACCCGGTGTTCAGCG
ATTACGCGGCGCCGTTCTCTTTTATCAATAAAGCCTTCCCCGGCGACTATCCGTGGCGGGCGGAAGGGATGCCGGAGATC
GATCTGCTGATCATCTCCCACGATCACTACGACCATCTGGATTACGCCACCATTCGCGCCTTACTGCCGAAAATTAAGCG
GGTCATTACGCCGCTGGGGGTCGGATCGCATCTGCGCTACTGGGGAATGGACGGAGCGCTGATTACCGAAGCGGACTGGC
AGCAGGCGGTACCGGCCAGCGACGAGCTCACCGTCCACGTGCTGCCGGCGCGGCACTTTTCCGGCCGTGGGCTGAAGCGT
AACCAGACGCTGTGGGCCAGTTTTCTGTTCGTTACCCGGCAGCAAAAGATTTATTACAGTGGCGACAGCGGGTATGGGCC
GCACTTTAAAGCGATAGGCGATGAGTTCGGTCCGGTCGATCTGGCGATCATGGAGAACGGGCAGTATGACCAGGACTGGA
AATATATCCACATGATGCCGGATGAAACGGCTCAGGCTGCCGACGACCTGCGCGCTCGCGCGGTGCTGCCTGGGCATGCA
GGACGATTCGTTTTGGCGAAACACAGCTGGGATGAACCGTATCAACGGCTGGCGGCTGCCAGCGAAGGAAGGGCCTGGCG
TCTGCTGACGCCTGTGCAGGGCGAGCCGGTGTGGGTCGCCGATAAGACGCAATCATTTAACGCCTGGTGGCGCTAA

Upstream 100 bases:

>100_bases
AAATTGAAAATCGTCTTGACGACTTTCATCGCTTTCCTAATAATGAGTGCGTACTCACTCATAATCAAGTTATATCATAA
AGCCTCCGGGATGGGGGCTT

Downstream 100 bases:

>100_bases
GCGCCAGTGCAGTATCAGAGGAGAGAGCATATGACGATTTCCGCTCAGGTGATTGATACTATCGTCGAGTGGATTGATGA
TAACCTGCATCAACCGCTGC

Product: beta-lactamase domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSGQDMNRVTFSVVAIMLLAAATTLPFVLNAGFGKAPQGAQLSQVEASPHYRDGQFHNQLPTPGFTGQKNMLAAWWDFLM
TKRENARPAQPLPLVKTDLATLPLGQDVMVWLGHSSWYLQLAGKRILIDPVFSDYAAPFSFINKAFPGDYPWRAEGMPEI
DLLIISHDHYDHLDYATIRALLPKIKRVITPLGVGSHLRYWGMDGALITEADWQQAVPASDELTVHVLPARHFSGRGLKR
NQTLWASFLFVTRQQKIYYSGDSGYGPHFKAIGDEFGPVDLAIMENGQYDQDWKYIHMMPDETAQAADDLRARAVLPGHA
GRFVLAKHSWDEPYQRLAAASEGRAWRLLTPVQGEPVWVADKTQSFNAWWR

Sequences:

>Translated_371_residues
MSGQDMNRVTFSVVAIMLLAAATTLPFVLNAGFGKAPQGAQLSQVEASPHYRDGQFHNQLPTPGFTGQKNMLAAWWDFLM
TKRENARPAQPLPLVKTDLATLPLGQDVMVWLGHSSWYLQLAGKRILIDPVFSDYAAPFSFINKAFPGDYPWRAEGMPEI
DLLIISHDHYDHLDYATIRALLPKIKRVITPLGVGSHLRYWGMDGALITEADWQQAVPASDELTVHVLPARHFSGRGLKR
NQTLWASFLFVTRQQKIYYSGDSGYGPHFKAIGDEFGPVDLAIMENGQYDQDWKYIHMMPDETAQAADDLRARAVLPGHA
GRFVLAKHSWDEPYQRLAAASEGRAWRLLTPVQGEPVWVADKTQSFNAWWR
>Mature_370_residues
SGQDMNRVTFSVVAIMLLAAATTLPFVLNAGFGKAPQGAQLSQVEASPHYRDGQFHNQLPTPGFTGQKNMLAAWWDFLMT
KRENARPAQPLPLVKTDLATLPLGQDVMVWLGHSSWYLQLAGKRILIDPVFSDYAAPFSFINKAFPGDYPWRAEGMPEID
LLIISHDHYDHLDYATIRALLPKIKRVITPLGVGSHLRYWGMDGALITEADWQQAVPASDELTVHVLPARHFSGRGLKRN
QTLWASFLFVTRQQKIYYSGDSGYGPHFKAIGDEFGPVDLAIMENGQYDQDWKYIHMMPDETAQAADDLRARAVLPGHAG
RFVLAKHSWDEPYQRLAAASEGRAWRLLTPVQGEPVWVADKTQSFNAWWR

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=318, Percent_Identity=31.4465408805031, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI170932481, Length=318, Percent_Identity=31.4465408805031, Blast_Score=145, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17543104, Length=252, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI25148824, Length=257, Percent_Identity=32.6848249027237, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17543102, Length=257, Percent_Identity=32.6848249027237, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17543100, Length=257, Percent_Identity=32.6848249027237, Blast_Score=124, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6325154, Length=270, Percent_Identity=33.7037037037037, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41729; Mature: 41598

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQDMNRVTFSVVAIMLLAAATTLPFVLNAGFGKAPQGAQLSQVEASPHYRDGQFHNQL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEECCCCCCCCCCCCCCC
PTPGFTGQKNMLAAWWDFLMTKRENARPAQPLPLVKTDLATLPLGQDVMVWLGHSSWYLQ
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCEEEE
LAGKRILIDPVFSDYAAPFSFINKAFPGDYPWRAEGMPEIDLLIISHDHYDHLDYATIRA
ECCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHH
LLPKIKRVITPLGVGSHLRYWGMDGALITEADWQQAVPASDELTVHVLPARHFSGRGLKR
HHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHCCCCCCCEEEEEEECCCCCCCCCCC
NQTLWASFLFVTRQQKIYYSGDSGYGPHFKAIGDEFGPVDLAIMENGQYDQDWKYIHMMP
CHHHHHHHHEEEECCEEEECCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCEEEEECC
DETAQAADDLRARAVLPGHAGRFVLAKHSWDEPYQRLAAASEGRAWRLLTPVQGEPVWVA
CCHHHHHHHHHHEEECCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCCCEEEEE
DKTQSFNAWWR
CCCCCCCCCCC
>Mature Secondary Structure 
SGQDMNRVTFSVVAIMLLAAATTLPFVLNAGFGKAPQGAQLSQVEASPHYRDGQFHNQL
CCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEECCCCCCCCCCCCCCC
PTPGFTGQKNMLAAWWDFLMTKRENARPAQPLPLVKTDLATLPLGQDVMVWLGHSSWYLQ
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCEEEE
LAGKRILIDPVFSDYAAPFSFINKAFPGDYPWRAEGMPEIDLLIISHDHYDHLDYATIRA
ECCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHH
LLPKIKRVITPLGVGSHLRYWGMDGALITEADWQQAVPASDELTVHVLPARHFSGRGLKR
HHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHCCCCCCCEEEEEEECCCCCCCCCCC
NQTLWASFLFVTRQQKIYYSGDSGYGPHFKAIGDEFGPVDLAIMENGQYDQDWKYIHMMP
CHHHHHHHHEEEECCEEEECCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCEEEEECC
DETAQAADDLRARAVLPGHAGRFVLAKHSWDEPYQRLAAASEGRAWRLLTPVQGEPVWVA
CCHHHHHHHHHHEEECCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCCCEEEEE
DKTQSFNAWWR
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]