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The map label for this gene is scrK [H]

Identifier: 238893531

GI number: 238893531

Start: 1379053

End: 1379976

Strand: Reverse

Name: scrK [H]

Synonym: KP1_1434

Alternate gene names: 238893531

Gene position: 1379976-1379053 (Counterclockwise)

Preceding gene: 238893536

Following gene: 238893530

Centisome position: 26.29

GC content: 67.42

Gene sequence:

>924_bases
ATGAATGGAAAAATCTGGGTACTCGGCGATGCGGTCGTCGATCTCCTGCCCGATGGAGAGGGCCGCCTGCTGCAATGCCC
CGGCGGCGCGCCGGCCAACGTGGCGGTCGGCGTGGCGCGGCTCGGCGGTGACAGCGGGTTTATCGGCCGCGTCGGCGACG
ATCCCTTCGGCCGTTTTATGCGTCACACCCTGGCGCAGGAGCAGGTGGATGTGAACTATATGCGCCTCGATGCGGCGCAG
CGCACCTCCACGGTGGTGGTCGATCTCGATAGTCACGGGGAGCGCACCTTTACCTTTATGGTCCGTCCGAGCGCCGACCT
GTTCCTTCAGCCCGAGGATCTCCCGCCGTTTGCCGCCGGTCAGTGGCTGCACGTCTGCTCCATCGCTCTCAGCGCGGAAC
CGAGCCGCAGCACGACATTCGCGGCGATGGAGGCGATAAAGCGCGCCGGGGGCTATGTCAGCTTCGACCCCAATATCCGC
AGCGACCTGTGGCAGGATCCGCAGGACCTTCGCGACTGTCTCGACCGGGCGCTGGCCCTCGCCGACGCCATAAAACTTTC
GGAAGAGGAGCTGGCGTTTATCAGCGGCAGCGACGACATCGTCAGCGGCATCGCCCGGCTGAACGCCCGCTTCCAGCCGA
CGCTACTGCTGGTGACCCAGGGTAAAGCGGGGGTCCAGGCCGCCCTGCGCGGGCAGGTTAGCCACTTCCCTGCCCGCCCG
GTGGTGGCCGTCGATACCACCGGCGCCGGCGATGCCTTTGTCGCCGGGCTACTCGCCGGCCTCGCCGCCCACGGTATCCC
GGATAACCTCGCAGCCCTGGCTCCCGACCTCGCGCTGGCGCAAACCTGCGGCGCGCTGGCCACCACCGCCAAAGGCGCCA
TGACCGCCCTGCCCTACAGGGACGATCTTCAGCGCTCGCTGTGA

Upstream 100 bases:

>100_bases
CGCCTCCCTGTTTCGTGACCCAATCGTTCCGCTTACCGGTGGGCTGTGCTTTAATGAGCTAAACCGGTTTAATAAAGTTT
AGCTTAGAGGAGCTTGTCGT

Downstream 100 bases:

>100_bases
TCCCCTTGGGCCGGTTAACGGCCCACTTTGCTGGCGACATCACAATTCTTAAACCGGTTTAGCAATTTTTATTTTCACCG
CGTTACCGACATGTTTACCA

Product: aminoimidazole riboside kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNGKIWVLGDAVVDLLPDGEGRLLQCPGGAPANVAVGVARLGGDSGFIGRVGDDPFGRFMRHTLAQEQVDVNYMRLDAAQ
RTSTVVVDLDSHGERTFTFMVRPSADLFLQPEDLPPFAAGQWLHVCSIALSAEPSRSTTFAAMEAIKRAGGYVSFDPNIR
SDLWQDPQDLRDCLDRALALADAIKLSEEELAFISGSDDIVSGIARLNARFQPTLLLVTQGKAGVQAALRGQVSHFPARP
VVAVDTTGAGDAFVAGLLAGLAAHGIPDNLAALAPDLALAQTCGALATTAKGAMTALPYRDDLQRSL

Sequences:

>Translated_307_residues
MNGKIWVLGDAVVDLLPDGEGRLLQCPGGAPANVAVGVARLGGDSGFIGRVGDDPFGRFMRHTLAQEQVDVNYMRLDAAQ
RTSTVVVDLDSHGERTFTFMVRPSADLFLQPEDLPPFAAGQWLHVCSIALSAEPSRSTTFAAMEAIKRAGGYVSFDPNIR
SDLWQDPQDLRDCLDRALALADAIKLSEEELAFISGSDDIVSGIARLNARFQPTLLLVTQGKAGVQAALRGQVSHFPARP
VVAVDTTGAGDAFVAGLLAGLAAHGIPDNLAALAPDLALAQTCGALATTAKGAMTALPYRDDLQRSL
>Mature_307_residues
MNGKIWVLGDAVVDLLPDGEGRLLQCPGGAPANVAVGVARLGGDSGFIGRVGDDPFGRFMRHTLAQEQVDVNYMRLDAAQ
RTSTVVVDLDSHGERTFTFMVRPSADLFLQPEDLPPFAAGQWLHVCSIALSAEPSRSTTFAAMEAIKRAGGYVSFDPNIR
SDLWQDPQDLRDCLDRALALADAIKLSEEELAFISGSDDIVSGIARLNARFQPTLLLVTQGKAGVQAALRGQVSHFPARP
VVAVDTTGAGDAFVAGLLAGLAAHGIPDNLAALAPDLALAQTCGALATTAKGAMTALPYRDDLQRSL

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=294, Percent_Identity=28.9115646258503, Blast_Score=78, Evalue=8e-15,
Organism=Escherichia coli, GI87082343, Length=291, Percent_Identity=30.2405498281787, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790193, Length=280, Percent_Identity=25.3571428571429, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082281, Length=277, Percent_Identity=25.2707581227437, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=330, Percent_Identity=29.0909090909091, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.4 [H]

Molecular weight: Translated: 32390; Mature: 32390

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGKIWVLGDAVVDLLPDGEGRLLQCPGGAPANVAVGVARLGGDSGFIGRVGDDPFGRFM
CCCEEEEEEHHHHHHCCCCCCCEEECCCCCCCHHEEEEEEECCCCCCEECCCCCHHHHHH
RHTLAQEQVDVNYMRLDAAQRTSTVVVDLDSHGERTFTFMVRPSADLFLQPEDLPPFAAG
HHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCCEEECCCCCCCCCCC
QWLHVCSIALSAEPSRSTTFAAMEAIKRAGGYVSFDPNIRSDLWQDPQDLRDCLDRALAL
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCHHHCCCHHHHHHHHHHHHHH
ADAIKLSEEELAFISGSDDIVSGIARLNARFQPTLLLVTQGKAGVQAALRGQVSHFPARP
HHHHHCCHHHEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCC
VVAVDTTGAGDAFVAGLLAGLAAHGIPDNLAALAPDLALAQTCGALATTAKGAMTALPYR
EEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCH
DDLQRSL
HHHHHCC
>Mature Secondary Structure
MNGKIWVLGDAVVDLLPDGEGRLLQCPGGAPANVAVGVARLGGDSGFIGRVGDDPFGRFM
CCCEEEEEEHHHHHHCCCCCCCEEECCCCCCCHHEEEEEEECCCCCCEECCCCCHHHHHH
RHTLAQEQVDVNYMRLDAAQRTSTVVVDLDSHGERTFTFMVRPSADLFLQPEDLPPFAAG
HHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCCEEECCCCCCCCCCC
QWLHVCSIALSAEPSRSTTFAAMEAIKRAGGYVSFDPNIRSDLWQDPQDLRDCLDRALAL
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCHHHCCCHHHHHHHHHHHHHH
ADAIKLSEEELAFISGSDDIVSGIARLNARFQPTLLLVTQGKAGVQAALRGQVSHFPARP
HHHHHCCHHHEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCC
VVAVDTTGAGDAFVAGLLAGLAAHGIPDNLAALAPDLALAQTCGALATTAKGAMTALPYR
EEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCH
DDLQRSL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1809835 [H]