| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is ybbO [H]
Identifier: 238893459
GI number: 238893459
Start: 1303053
End: 1303862
Strand: Reverse
Name: ybbO [H]
Synonym: KP1_1350
Alternate gene names: 238893459
Gene position: 1303862-1303053 (Counterclockwise)
Preceding gene: 238893460
Following gene: 238893458
Centisome position: 24.84
GC content: 60.49
Gene sequence:
>810_bases ATGACTCCTGAACGCCAGGGGTCGCTGACAGGTAAAGTTATGCAAAAAACGGTTTTAGTGACAGGCTGTTCCAGCGGAAT TGGTCTGGAAAGCGCGCTGGATTTAACCCGCCAGGGCTTTCGCGTGCTGGCGGCCTGCCGCAAAGCAGAGGATGTCGCGC GGATGCAGGAGCTGGGGCTAACCGGTATTTTGCTCGATCTGGATGACCCGCAGAGCGTGGAGCGCGCGGCAGCGGAGGTG ATTGCGCTGACCGATAATCGTCTCTACGGCCTGTTCAATAACGCCGGGTATGGCGTCTATGGCCCGCTGAACACCATCAG CCGCCAGCAGATGGAACAGCAATTTTCCGCTAACTTTTTCGGCGCGCATCAGCTCACCATGCTGCTGCTGCCGGCGATGA CGCCGCACGGCGAAGGACGCATCGTGATGACCTCCTCGGTGATGGGGCTTATCGCCAGTCCCGGCCGCGGAGCCTATGCC GCCAGTAAATATGCCCTCGAGGCGTGGTCCGACGCGCTGCGCATGGAGCTGCGCCACAGCGGTATTCAGGTCAGCCTGAT TGAACCGGGCCCGATCCGCACCCGCTTTACCGATAACGTCAACCAGACGCAAAGCGATAAGCCCGTAGAAAATCCGGGCA TCGCCGCCCGCTTTACCCTCGGGCCGGAGGCGGTGGTGGAAAAAGTGCGCCATGCTTTTACCAGCGATAAACCAAAGCTG CGCTATCCGGTCACCCTGGTCACCCACGCGGTGGCGCTGCTTAAGCGCCTGCTGCCTGCCCGCGCGATGGACAAAATTAT CCACGGCTGA
Upstream 100 bases:
>100_bases AAGCCGCAATGGATGCAGGACGACGGCATTCATCCAAATCGCGACGCGCAGCCGTTTATCGCCGACTGGATGGCGAAGCG GCTGGCTCCCTTAGTTAATC
Downstream 100 bases:
>100_bases GTTGAAGCGCGGAATGCCGCCCCCATGTAAAACAGAAATCGACTAACGAGAAATGCCCATGTCCGAACAGAATATTGTCA ACATTAGCGAAGCGAACCTG
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 269; Mature: 268
Protein sequence:
>269_residues MTPERQGSLTGKVMQKTVLVTGCSSGIGLESALDLTRQGFRVLAACRKAEDVARMQELGLTGILLDLDDPQSVERAAAEV IALTDNRLYGLFNNAGYGVYGPLNTISRQQMEQQFSANFFGAHQLTMLLLPAMTPHGEGRIVMTSSVMGLIASPGRGAYA ASKYALEAWSDALRMELRHSGIQVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVEKVRHAFTSDKPKL RYPVTLVTHAVALLKRLLPARAMDKIIHG
Sequences:
>Translated_269_residues MTPERQGSLTGKVMQKTVLVTGCSSGIGLESALDLTRQGFRVLAACRKAEDVARMQELGLTGILLDLDDPQSVERAAAEV IALTDNRLYGLFNNAGYGVYGPLNTISRQQMEQQFSANFFGAHQLTMLLLPAMTPHGEGRIVMTSSVMGLIASPGRGAYA ASKYALEAWSDALRMELRHSGIQVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVEKVRHAFTSDKPKL RYPVTLVTHAVALLKRLLPARAMDKIIHG >Mature_268_residues TPERQGSLTGKVMQKTVLVTGCSSGIGLESALDLTRQGFRVLAACRKAEDVARMQELGLTGILLDLDDPQSVERAAAEVI ALTDNRLYGLFNNAGYGVYGPLNTISRQQMEQQFSANFFGAHQLTMLLLPAMTPHGEGRIVMTSSVMGLIASPGRGAYAA SKYALEAWSDALRMELRHSGIQVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVEKVRHAFTSDKPKLR YPVTLVTHAVALLKRLLPARAMDKIIHG
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI50726952, Length=186, Percent_Identity=42.4731182795699, Blast_Score=125, Evalue=5e-29, Organism=Homo sapiens, GI7657478, Length=251, Percent_Identity=34.2629482071713, Blast_Score=122, Evalue=4e-28, Organism=Homo sapiens, GI40548397, Length=271, Percent_Identity=31.7343173431734, Blast_Score=122, Evalue=4e-28, Organism=Homo sapiens, GI214010158, Length=271, Percent_Identity=31.7343173431734, Blast_Score=122, Evalue=4e-28, Organism=Homo sapiens, GI214010156, Length=271, Percent_Identity=31.7343173431734, Blast_Score=122, Evalue=4e-28, Organism=Homo sapiens, GI22758144, Length=271, Percent_Identity=31.7343173431734, Blast_Score=122, Evalue=4e-28, Organism=Homo sapiens, GI22507405, Length=257, Percent_Identity=31.1284046692607, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI150247226, Length=291, Percent_Identity=30.5841924398625, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI223718074, Length=259, Percent_Identity=32.8185328185328, Blast_Score=108, Evalue=7e-24, Organism=Homo sapiens, GI19743808, Length=292, Percent_Identity=30.4794520547945, Blast_Score=107, Evalue=8e-24, Organism=Homo sapiens, GI44680136, Length=195, Percent_Identity=32.8205128205128, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI44680133, Length=195, Percent_Identity=32.8205128205128, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI17738292, Length=195, Percent_Identity=32.8205128205128, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=31.8181818181818, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI119392083, Length=207, Percent_Identity=35.7487922705314, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI7706318, Length=207, Percent_Identity=31.8840579710145, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI157739938, Length=197, Percent_Identity=31.4720812182741, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI142976729, Length=271, Percent_Identity=27.3062730627306, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI4504503, Length=206, Percent_Identity=30.5825242718447, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI210032110, Length=206, Percent_Identity=28.6407766990291, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI32483357, Length=189, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI32455239, Length=181, Percent_Identity=30.3867403314917, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI5031765, Length=181, Percent_Identity=30.3867403314917, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI4503817, Length=227, Percent_Identity=26.8722466960352, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1786701, Length=269, Percent_Identity=82.5278810408922, Blast_Score=466, Evalue=1e-133, Organism=Escherichia coli, GI87082100, Length=205, Percent_Identity=33.1707317073171, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1789378, Length=211, Percent_Identity=31.2796208530806, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1787335, Length=192, Percent_Identity=29.6875, Blast_Score=72, Evalue=5e-14, Organism=Escherichia coli, GI2367365, Length=191, Percent_Identity=31.413612565445, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1786812, Length=207, Percent_Identity=28.0193236714976, Blast_Score=64, Evalue=7e-12, Organism=Escherichia coli, GI1787820, Length=219, Percent_Identity=29.6803652968037, Blast_Score=64, Evalue=8e-12, Organism=Escherichia coli, GI1788459, Length=211, Percent_Identity=29.8578199052133, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787526, Length=206, Percent_Identity=31.0679611650485, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI115534660, Length=286, Percent_Identity=28.3216783216783, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI193210355, Length=282, Percent_Identity=30.1418439716312, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17557780, Length=265, Percent_Identity=27.1698113207547, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI71997402, Length=192, Percent_Identity=32.2916666666667, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17570069, Length=198, Percent_Identity=31.8181818181818, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI32563809, Length=288, Percent_Identity=25.3472222222222, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17507613, Length=288, Percent_Identity=25.3472222222222, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI32563807, Length=189, Percent_Identity=27.5132275132275, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17560676, Length=225, Percent_Identity=27.5555555555556, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17561402, Length=193, Percent_Identity=26.9430051813472, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322067, Length=193, Percent_Identity=30.5699481865285, Blast_Score=78, Evalue=1e-15, Organism=Saccharomyces cerevisiae, GI6323882, Length=203, Percent_Identity=30.5418719211823, Blast_Score=75, Evalue=1e-14, Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=36.5979381443299, Blast_Score=111, Evalue=6e-25, Organism=Drosophila melanogaster, GI24651139, Length=243, Percent_Identity=31.6872427983539, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI21356301, Length=214, Percent_Identity=30.3738317757009, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI28571526, Length=186, Percent_Identity=31.7204301075269, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI45554248, Length=200, Percent_Identity=34.5, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24640117, Length=200, Percent_Identity=34.5, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24580925, Length=198, Percent_Identity=30.8080808080808, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24643142, Length=198, Percent_Identity=29.2929292929293, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24644339, Length=194, Percent_Identity=29.8969072164948, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI45553409, Length=205, Percent_Identity=29.7560975609756, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI24647948, Length=205, Percent_Identity=29.7560975609756, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI24647946, Length=209, Percent_Identity=29.6650717703349, Blast_Score=71, Evalue=9e-13, Organism=Drosophila melanogaster, GI21357041, Length=189, Percent_Identity=28.042328042328, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI21355319, Length=197, Percent_Identity=27.9187817258883, Blast_Score=64, Evalue=1e-10,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 29228; Mature: 29097
Theoretical pI: Translated: 9.39; Mature: 9.39
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 3.7 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 3.4 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTPERQGSLTGKVMQKTVLVTGCSSGIGLESALDLTRQGFRVLAACRKAEDVARMQELGL CCCCCCCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC TGILLDLDDPQSVERAAAEVIALTDNRLYGLFNNAGYGVYGPLNTISRQQMEQQFSANFF EEEEEECCCCHHHHHHHHHEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCC GAHQLTMLLLPAMTPHGEGRIVMTSSVMGLIASPGRGAYAASKYALEAWSDALRMELRHS CHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC GIQVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVEKVRHAFTSDKPKL CEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCE RYPVTLVTHAVALLKRLLPARAMDKIIHG ECHHHHHHHHHHHHHHHHHHHHHHHHHCC >Mature Secondary Structure TPERQGSLTGKVMQKTVLVTGCSSGIGLESALDLTRQGFRVLAACRKAEDVARMQELGL CCCCCCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC TGILLDLDDPQSVERAAAEVIALTDNRLYGLFNNAGYGVYGPLNTISRQQMEQQFSANFF EEEEEECCCCHHHHHHHHHEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCC GAHQLTMLLLPAMTPHGEGRIVMTSSVMGLIASPGRGAYAASKYALEAWSDALRMELRHS CHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC GIQVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVEKVRHAFTSDKPKL CEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCE RYPVTLVTHAVALLKRLLPARAMDKIIHG ECHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 12471157 [H]