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The map label for this gene is yajO [H]

Identifier: 238893356

GI number: 238893356

Start: 1195209

End: 1196183

Strand: Reverse

Name: yajO [H]

Synonym: KP1_1237

Alternate gene names: 238893356

Gene position: 1196183-1195209 (Counterclockwise)

Preceding gene: 238893357

Following gene: 238893349

Centisome position: 22.79

GC content: 62.77

Gene sequence:

>975_bases
ATGCACTATATCCCCCTCGGTGATACTGCCTTACGTGTTTCCCGACTCTGCCTCGGCTGCATGACCTTCGGCGAGCCGGA
CCGCGGCAGACACGCCTGGACGCTTCCGGAAGAGAGCAGCCGCCCGCTTATCCAGCACGCCATTGAAGGCGGCATCAACT
TCTTCGATACCGCAAATAGCTACTCCGACGGCAGCAGCGAAGAGATCGTTGGCCGCGCCCTGCGCGACTTTGCCCGCCGT
GACGAGGTGGTTGTCGCCACCAAGGTGTATCACCAGGTCGGCGATCTGGCGGAAGGACTTTCCCGGGCGCAGATCCTGCG
CTCCATCGACGACAGCCTGCGCCGTCTCGGGATGGACTATGTCGACCTGCTGCAGATCCACCGCTGGGACTATACCACCC
CGATTGAAGAGACGCTCGAAGCGCTGGACGAGGTGGTGAAAGCCGGCAAAGCGCGCTATATCGGCGCCTCGTCCATGCAT
GCCCGACAGTTTGCCCAGGCGCTGGCGCTCCAGCAGCAGAACGGCTGGGCGCGCTTCGTCACCATGCAGGATCACTACAA
CCTGATTTACCGGGAAGAAGAGAATGAGATGCTGCCCCTGTGCCAACGTAACGGCGTAGCGGTGATCCCATGGAGTCCGC
TGGCGCGCGGCAGGCTAACCCGCCCCTGGGGTGAGACCACCGCCCGGCTGGTCTCAGATGAGTTCGGCAAATCGCTGTAC
AGCGCCAGTGAAGAAAACGATGCGCAGATCGCCGGGAATCTCGCGGACGTGGCGGAAGAACTCGACGCCAGCCGCGCCCA
GGTCGCCCTCGCCTGGCTGTTAAGCAAACCCGGCGTCGCCGCGCCGATTATCGGCCCGTCGCGTCAGGAACAGCTCGATG
ATCTGCTGCAGGCGGTGGATTTGACGCTCTCCCCGGAACAGATCGACAAGCTGGAGGCGCCGTATCAGCCGCATCCGGTG
GTGGGATTTAAGTGA

Upstream 100 bases:

>100_bases
CGCCGGTATTGAAGCCAAAATCCGCGACTGGCTGGCATAATTGCCCCTTCCGCTCCTGCTATGCTTAAGGGATACCCTTG
ATGAATAGCAGGAGCGCACT

Downstream 100 bases:

>100_bases
AGGGCGTGGTTTCCCCGGCAGCGTAGCGTTGCCGGGGAGAGGCGGTTAAAGCAGACCGATGGGCCAGTGATGGCCAATGA
CGTACAGCACGCCGGCGGAG

Product: putative NAD(P)H-dependent xylose reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MHYIPLGDTALRVSRLCLGCMTFGEPDRGRHAWTLPEESSRPLIQHAIEGGINFFDTANSYSDGSSEEIVGRALRDFARR
DEVVVATKVYHQVGDLAEGLSRAQILRSIDDSLRRLGMDYVDLLQIHRWDYTTPIEETLEALDEVVKAGKARYIGASSMH
ARQFAQALALQQQNGWARFVTMQDHYNLIYREEENEMLPLCQRNGVAVIPWSPLARGRLTRPWGETTARLVSDEFGKSLY
SASEENDAQIAGNLADVAEELDASRAQVALAWLLSKPGVAAPIIGPSRQEQLDDLLQAVDLTLSPEQIDKLEAPYQPHPV
VGFK

Sequences:

>Translated_324_residues
MHYIPLGDTALRVSRLCLGCMTFGEPDRGRHAWTLPEESSRPLIQHAIEGGINFFDTANSYSDGSSEEIVGRALRDFARR
DEVVVATKVYHQVGDLAEGLSRAQILRSIDDSLRRLGMDYVDLLQIHRWDYTTPIEETLEALDEVVKAGKARYIGASSMH
ARQFAQALALQQQNGWARFVTMQDHYNLIYREEENEMLPLCQRNGVAVIPWSPLARGRLTRPWGETTARLVSDEFGKSLY
SASEENDAQIAGNLADVAEELDASRAQVALAWLLSKPGVAAPIIGPSRQEQLDDLLQAVDLTLSPEQIDKLEAPYQPHPV
VGFK
>Mature_324_residues
MHYIPLGDTALRVSRLCLGCMTFGEPDRGRHAWTLPEESSRPLIQHAIEGGINFFDTANSYSDGSSEEIVGRALRDFARR
DEVVVATKVYHQVGDLAEGLSRAQILRSIDDSLRRLGMDYVDLLQIHRWDYTTPIEETLEALDEVVKAGKARYIGASSMH
ARQFAQALALQQQNGWARFVTMQDHYNLIYREEENEMLPLCQRNGVAVIPWSPLARGRLTRPWGETTARLVSDEFGKSLY
SASEENDAQIAGNLADVAEELDASRAQVALAWLLSKPGVAAPIIGPSRQEQLDDLLQAVDLTLSPEQIDKLEAPYQPHPV
VGFK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=313, Percent_Identity=34.185303514377, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI27436962, Length=313, Percent_Identity=34.185303514377, Blast_Score=144, Evalue=9e-35,
Organism=Homo sapiens, GI27436966, Length=313, Percent_Identity=33.8658146964856, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI27436969, Length=314, Percent_Identity=32.8025477707006, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI4504825, Length=312, Percent_Identity=32.6923076923077, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI27436971, Length=335, Percent_Identity=32.2388059701493, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI223718702, Length=286, Percent_Identity=29.020979020979, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI41152114, Length=286, Percent_Identity=28.6713286713287, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI41327764, Length=174, Percent_Identity=33.9080459770115, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI223718708, Length=130, Percent_Identity=35.3846153846154, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=84.2592592592593, Blast_Score=571, Evalue=1e-164,
Organism=Escherichia coli, GI1789375, Length=328, Percent_Identity=35.9756097560976, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788070, Length=328, Percent_Identity=32.6219512195122, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=29.5977011494253, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788081, Length=262, Percent_Identity=30.9160305343511, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787674, Length=316, Percent_Identity=28.1645569620253, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI48994888, Length=290, Percent_Identity=27.2413793103448, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI212645785, Length=308, Percent_Identity=27.5974025974026, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17550248, Length=287, Percent_Identity=26.4808362369338, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=336, Percent_Identity=37.202380952381, Blast_Score=236, Evalue=3e-63,
Organism=Saccharomyces cerevisiae, GI6323998, Length=316, Percent_Identity=30.379746835443, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6319958, Length=304, Percent_Identity=30.5921052631579, Blast_Score=136, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6319951, Length=316, Percent_Identity=29.4303797468354, Blast_Score=131, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6322615, Length=246, Percent_Identity=30.4878048780488, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6321052, Length=156, Percent_Identity=32.6923076923077, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640980, Length=345, Percent_Identity=27.536231884058, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI45549126, Length=345, Percent_Identity=27.536231884058, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24646155, Length=327, Percent_Identity=29.6636085626911, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24646159, Length=299, Percent_Identity=28.7625418060201, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36155; Mature: 36155

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYIPLGDTALRVSRLCLGCMTFGEPDRGRHAWTLPEESSRPLIQHAIEGGINFFDTANS
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHCCCEEHCCCCC
YSDGSSEEIVGRALRDFARRDEVVVATKVYHQVGDLAEGLSRAQILRSIDDSLRRLGMDY
CCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VDLLQIHRWDYTTPIEETLEALDEVVKAGKARYIGASSMHARQFAQALALQQQNGWARFV
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHCCCCEEEE
TMQDHYNLIYREEENEMLPLCQRNGVAVIPWSPLARGRLTRPWGETTARLVSDEFGKSLY
EEECCCCEEEECCCCCCCCHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
SASEENDAQIAGNLADVAEELDASRAQVALAWLLSKPGVAAPIIGPSRQEQLDDLLQAVD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC
LTLSPEQIDKLEAPYQPHPVVGFK
CCCCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MHYIPLGDTALRVSRLCLGCMTFGEPDRGRHAWTLPEESSRPLIQHAIEGGINFFDTANS
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHCCCEEHCCCCC
YSDGSSEEIVGRALRDFARRDEVVVATKVYHQVGDLAEGLSRAQILRSIDDSLRRLGMDY
CCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VDLLQIHRWDYTTPIEETLEALDEVVKAGKARYIGASSMHARQFAQALALQQQNGWARFV
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHCCCCEEEE
TMQDHYNLIYREEENEMLPLCQRNGVAVIPWSPLARGRLTRPWGETTARLVSDEFGKSLY
EEECCCCEEEECCCCCCCCHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
SASEENDAQIAGNLADVAEELDASRAQVALAWLLSKPGVAAPIIGPSRQEQLDDLLQAVD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC
LTLSPEQIDKLEAPYQPHPVVGFK
CCCCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]