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The map label for this gene is ahpC [C]

Identifier: 238893338

GI number: 238893338

Start: 1180847

End: 1181449

Strand: Reverse

Name: ahpC [C]

Synonym: KP1_1218

Alternate gene names: 238893338

Gene position: 1181449-1180847 (Counterclockwise)

Preceding gene: 238893339

Following gene: 238893337

Centisome position: 22.51

GC content: 54.73

Gene sequence:

>603_bases
ATGGTTCTGGTCACTCGTCAAGCGCCGGATTTTACTGCAGCCGCTGTGCTGGGTAATGGTGAGATCGTTGAGAAATTCAA
TTTCAAACAGCACACCAACGGTAAACCTACCGTTCTGTTCTTCTGGCCGATGGACTTCACCTTCGTGTGCCCGTCTGAGC
TGATCGCGTTCGACAAACGTTACGAAGAATTCCAGAAACGCGGCGTGGAAGTGGTTGGCGTTTCCTTCGACTCCGAATTC
GTGCACAACGCATGGCGTAACACCCCGGTAGACCAGGGCGGTATCGGCCCGGTTAAATACGCGATGGTTGCTGACATCAA
ACGTGAAATCCAGAAAGCTTACGGTATCGAGCATCCGGACGAAGGCGTAGCGCTGCGCGGCTCTTTCCTGATCGACGCCA
ACGGCATCGTTCGTCATCAGGTGGTTAACGACCTGCCGCTGGGCCGTAACATCGACGAAATGCTGCGTATGGTAGACGCC
CTGCAGTTCCACGAAGAGCACGGCGAAGTCTGCCCGGCGCAGTGGGAAAAAGGAAAAGAAGGTATGGCCGCCTCTCCGGA
AGGCGTAGCAAAATACCTGACCGAAAACGTCTCCAGCCTGTAA

Upstream 100 bases:

>100_bases
GGCTGAACGATTGTTAGCGCCTCTTTGTGTTATTGCCGGGCAGGCTCTATACTTGCCCGCGTTGCGTTCCAAATAACCTT
AGTAATTACAGGAGAATCAA

Downstream 100 bases:

>100_bases
TCGGCACGCGTTTTAATAAAAGGCTCGCTCAGGCGGGCCTTTTTTGTTAGCGGCGTCAAAATTTAAGAAAATGACCCGCC
GATATTTGTGACCAGCGATA

Product: putative thiol-alkyl hydroperoxide reductase

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MVLVTRQAPDFTAAAVLGNGEIVEKFNFKQHTNGKPTVLFFWPMDFTFVCPSELIAFDKRYEEFQKRGVEVVGVSFDSEF
VHNAWRNTPVDQGGIGPVKYAMVADIKREIQKAYGIEHPDEGVALRGSFLIDANGIVRHQVVNDLPLGRNIDEMLRMVDA
LQFHEEHGEVCPAQWEKGKEGMAASPEGVAKYLTENVSSL

Sequences:

>Translated_200_residues
MVLVTRQAPDFTAAAVLGNGEIVEKFNFKQHTNGKPTVLFFWPMDFTFVCPSELIAFDKRYEEFQKRGVEVVGVSFDSEF
VHNAWRNTPVDQGGIGPVKYAMVADIKREIQKAYGIEHPDEGVALRGSFLIDANGIVRHQVVNDLPLGRNIDEMLRMVDA
LQFHEEHGEVCPAQWEKGKEGMAASPEGVAKYLTENVSSL
>Mature_200_residues
MVLVTRQAPDFTAAAVLGNGEIVEKFNFKQHTNGKPTVLFFWPMDFTFVCPSELIAFDKRYEEFQKRGVEVVGVSFDSEF
VHNAWRNTPVDQGGIGPVKYAMVADIKREIQKAYGIEHPDEGVALRGSFLIDANGIVRHQVVNDLPLGRNIDEMLRMVDA
LQFHEEHGEVCPAQWEKGKEGMAASPEGVAKYLTENVSSL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=194, Percent_Identity=47.4226804123711, Blast_Score=197, Evalue=4e-51,
Organism=Homo sapiens, GI4505591, Length=191, Percent_Identity=47.1204188481675, Blast_Score=193, Evalue=1e-49,
Organism=Homo sapiens, GI32455266, Length=191, Percent_Identity=47.1204188481675, Blast_Score=193, Evalue=1e-49,
Organism=Homo sapiens, GI32455264, Length=191, Percent_Identity=47.1204188481675, Blast_Score=193, Evalue=1e-49,
Organism=Homo sapiens, GI5453549, Length=190, Percent_Identity=46.8421052631579, Blast_Score=186, Evalue=1e-47,
Organism=Homo sapiens, GI5802974, Length=192, Percent_Identity=46.3541666666667, Blast_Score=182, Evalue=2e-46,
Organism=Homo sapiens, GI32483377, Length=191, Percent_Identity=46.0732984293194, Blast_Score=180, Evalue=7e-46,
Organism=Homo sapiens, GI33188454, Length=83, Percent_Identity=53.0120481927711, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI4758638, Length=203, Percent_Identity=29.064039408867, Blast_Score=71, Evalue=8e-13,
Organism=Escherichia coli, GI1786822, Length=192, Percent_Identity=38.0208333333333, Blast_Score=130, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17554494, Length=184, Percent_Identity=45.1086956521739, Blast_Score=172, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI193204376, Length=194, Percent_Identity=44.8453608247423, Blast_Score=166, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI32565831, Length=194, Percent_Identity=44.8453608247423, Blast_Score=166, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI25153706, Length=184, Percent_Identity=29.8913043478261, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323613, Length=190, Percent_Identity=40, Blast_Score=161, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6320661, Length=175, Percent_Identity=41.7142857142857, Blast_Score=152, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6319407, Length=181, Percent_Identity=30.3867403314917, Blast_Score=86, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24656348, Length=194, Percent_Identity=47.4226804123711, Blast_Score=192, Evalue=1e-49,
Organism=Drosophila melanogaster, GI17864676, Length=194, Percent_Identity=47.4226804123711, Blast_Score=192, Evalue=1e-49,
Organism=Drosophila melanogaster, GI17738015, Length=197, Percent_Identity=44.1624365482233, Blast_Score=181, Evalue=4e-46,
Organism=Drosophila melanogaster, GI17157991, Length=193, Percent_Identity=42.4870466321244, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24641739, Length=193, Percent_Identity=42.4870466321244, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI21357347, Length=198, Percent_Identity=41.9191919191919, Blast_Score=165, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24581278, Length=203, Percent_Identity=30.0492610837438, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17975518, Length=156, Percent_Identity=32.6923076923077, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24652436, Length=156, Percent_Identity=32.6923076923077, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24652434, Length=156, Percent_Identity=32.6923076923077, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 22370; Mature: 22370

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLVTRQAPDFTAAAVLGNGEIVEKFNFKQHTNGKPTVLFFWPMDFTFVCPSELIAFDKR
CEEEECCCCCCEEEEEECCCCEEECCCCCCCCCCCCEEEEEECCCEEEECHHHHHHHHHH
YEEFQKRGVEVVGVSFDSEFVHNAWRNTPVDQGGIGPVKYAMVADIKREIQKAYGIEHPD
HHHHHHCCCEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
EGVALRGSFLIDANGIVRHQVVNDLPLGRNIDEMLRMVDALQFHEEHGEVCPAQWEKGKE
CCEEEEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCC
GMAASPEGVAKYLTENVSSL
CCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVLVTRQAPDFTAAAVLGNGEIVEKFNFKQHTNGKPTVLFFWPMDFTFVCPSELIAFDKR
CEEEECCCCCCEEEEEECCCCEEECCCCCCCCCCCCEEEEEECCCEEEECHHHHHHHHHH
YEEFQKRGVEVVGVSFDSEFVHNAWRNTPVDQGGIGPVKYAMVADIKREIQKAYGIEHPD
HHHHHHCCCEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
EGVALRGSFLIDANGIVRHQVVNDLPLGRNIDEMLRMVDALQFHEEHGEVCPAQWEKGKE
CCEEEEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCC
GMAASPEGVAKYLTENVSSL
CCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]