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The map label for this gene is ampH [H]

Identifier: 238893299

GI number: 238893299

Start: 1142732

End: 1143892

Strand: Reverse

Name: ampH [H]

Synonym: KP1_1176

Alternate gene names: 238893299

Gene position: 1143892-1142732 (Counterclockwise)

Preceding gene: 238893303

Following gene: 238893298

Centisome position: 21.79

GC content: 61.84

Gene sequence:

>1161_bases
TTGAAACGTAGTTTGCTCATTTTTGCTGCGCTGTGCGCGGCGTCGTGGACCTCGGTGCAGGCCGCACAGCCTACCGTTGA
CCCGGTTTTCGCCTCGGATGTGGTCGATCGTTACGCCAATCATATCTACTACGGCAGCGGCGCCACCGGCATGGCGCTGG
TGGTTATCGATGGCAATCAGCGTGTTTTTCGCAGCTTTGGCGAAACCCGCCCGGGGAATAATCAGCACCCGCAGCTCGAC
TCGGTGATCCGTATCGCCTCCCTCAGCAAACTGATGACCAGCGAGATGCTGGTGAAGCTGCTCGACCAGGGGGTGGTGAA
ACTCAACGATCCGCTGAGCAAATACGCCCCGCCAGGCGCCCGGGTGCCTGACTGGCAGGGAAAACCAATCACCCTGGTTA
ACCTCGCGACCCATACCAGCGCCCTGCCGCGCGAGCAGCCTGGCGGCGCCGCTCATCGTCCGGTGTTTGTCTGGCCGACC
CGCCAGCAGCGCTGGAACTGGCTCTCTACCGCGACCCTGAAAGCCGCGCCGGGCTCGCAGGCGGCCTACTCCAATCTGGC
CTTCGATTTACTGGCGGACGCGCTCGCCACCGCTGCCGGCAAACCGTATCCGCAGCTGTTTGAAGAGCAGATCACCCGGC
CGCTGGGGATGAAGGACACCACCTTTACCCCGTCACCGGATCAGTGCCAGCGGCTGATGATCCCGGAAAAAGGCGCCAGC
CCGTGCAACAACACCCTGGCGGCGATCGGCAGCGGCGGAGTCTACTCGACGCCGGGGGATATGATGCGCTGGATGCAGCA
GTTCCTGTCATCCGATTTCTATACCCGCAGCCAGCAGGCCGACCGGATGCAGACGCTGATTTATCAGCGTAACCAGCTGA
CCCGGGTGATTGGTATGGACGTGCCGGGCCGCGCAGACGCGCTGGGCCTCGGCTGGGTGTATATGAAGCCGAAGAACGGC
CATCCGGGGATTATTCAGAAAACCGGCGGCGGCGGCGGGTTTATCACCTATATGGCGATGAATCCGCAGGCTAACGTTGG
CGCCTTTGTAGTGGTAACCCGCTCGCCGTTAACCCGCTTCAACAATATGAGCGATGGCATCAACGACCTGGTCAGCGAGT
TGAGCGGCGCACAGCCCAACATGCAGACGGCCAGCCAGTAA

Upstream 100 bases:

>100_bases
TACCTTTTTCCTGCAGGAAAGTCGTGAATCCCGCTTTGTTCTGCGCCACTTCGTAGTATAAATACCCTCTTCTTTTTATT
TATTTAATGGATGATCTCCG

Downstream 100 bases:

>100_bases
GCCCGGGGAAGGTTTCGCCGATGCGCCATAACGATCGTTTTGGCGAAACATCCCGCTGCCATTTCAGTTACACTATCGTC
TTTCATTTCACAAAATCAGG

Product: beta-lactam binding protein AmpH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MKRSLLIFAALCAASWTSVQAAQPTVDPVFASDVVDRYANHIYYGSGATGMALVVIDGNQRVFRSFGETRPGNNQHPQLD
SVIRIASLSKLMTSEMLVKLLDQGVVKLNDPLSKYAPPGARVPDWQGKPITLVNLATHTSALPREQPGGAAHRPVFVWPT
RQQRWNWLSTATLKAAPGSQAAYSNLAFDLLADALATAAGKPYPQLFEEQITRPLGMKDTTFTPSPDQCQRLMIPEKGAS
PCNNTLAAIGSGGVYSTPGDMMRWMQQFLSSDFYTRSQQADRMQTLIYQRNQLTRVIGMDVPGRADALGLGWVYMKPKNG
HPGIIQKTGGGGGFITYMAMNPQANVGAFVVVTRSPLTRFNNMSDGINDLVSELSGAQPNMQTASQ

Sequences:

>Translated_386_residues
MKRSLLIFAALCAASWTSVQAAQPTVDPVFASDVVDRYANHIYYGSGATGMALVVIDGNQRVFRSFGETRPGNNQHPQLD
SVIRIASLSKLMTSEMLVKLLDQGVVKLNDPLSKYAPPGARVPDWQGKPITLVNLATHTSALPREQPGGAAHRPVFVWPT
RQQRWNWLSTATLKAAPGSQAAYSNLAFDLLADALATAAGKPYPQLFEEQITRPLGMKDTTFTPSPDQCQRLMIPEKGAS
PCNNTLAAIGSGGVYSTPGDMMRWMQQFLSSDFYTRSQQADRMQTLIYQRNQLTRVIGMDVPGRADALGLGWVYMKPKNG
HPGIIQKTGGGGGFITYMAMNPQANVGAFVVVTRSPLTRFNNMSDGINDLVSELSGAQPNMQTASQ
>Mature_386_residues
MKRSLLIFAALCAASWTSVQAAQPTVDPVFASDVVDRYANHIYYGSGATGMALVVIDGNQRVFRSFGETRPGNNQHPQLD
SVIRIASLSKLMTSEMLVKLLDQGVVKLNDPLSKYAPPGARVPDWQGKPITLVNLATHTSALPREQPGGAAHRPVFVWPT
RQQRWNWLSTATLKAAPGSQAAYSNLAFDLLADALATAAGKPYPQLFEEQITRPLGMKDTTFTPSPDQCQRLMIPEKGAS
PCNNTLAAIGSGGVYSTPGDMMRWMQQFLSSDFYTRSQQADRMQTLIYQRNQLTRVIGMDVPGRADALGLGWVYMKPKNG
HPGIIQKTGGGGGFITYMAMNPQANVGAFVVVTRSPLTRFNNMSDGINDLVSELSGAQPNMQTASQ

Specific function: Binds penicillin and contributes to the normal morphology [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI239747261, Length=284, Percent_Identity=29.5774647887324, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI239752721, Length=284, Percent_Identity=29.5774647887324, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI239741085, Length=284, Percent_Identity=29.5774647887324, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1786574, Length=385, Percent_Identity=85.7142857142857, Blast_Score=690, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 41938; Mature: 41938

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSLLIFAALCAASWTSVQAAQPTVDPVFASDVVDRYANHIYYGSGATGMALVVIDGNQ
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCEEEEEECCCH
RVFRSFGETRPGNNQHPQLDSVIRIASLSKLMTSEMLVKLLDQGVVKLNDPLSKYAPPGA
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHCCCCC
RVPDWQGKPITLVNLATHTSALPREQPGGAAHRPVFVWPTRQQRWNWLSTATLKAAPGSQ
CCCCCCCCCEEEEEECHHCCCCCCCCCCCCCCCCEEEECCHHHHCCCHHHEEEECCCCCH
AAYSNLAFDLLADALATAAGKPYPQLFEEQITRPLGMKDTTFTPSPDQCQRLMIPEKGAS
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHEEECCCCCCC
PCNNTLAAIGSGGVYSTPGDMMRWMQQFLSSDFYTRSQQADRMQTLIYQRNQLTRVIGMD
CCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPGRADALGLGWVYMKPKNGHPGIIQKTGGGGGFITYMAMNPQANVGAFVVVTRSPLTRF
CCCCCCEEEEEEEEEECCCCCCCCEEECCCCCEEEEEEEECCCCCCCEEEEEECCHHHHH
NNMSDGINDLVSELSGAQPNMQTASQ
CCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKRSLLIFAALCAASWTSVQAAQPTVDPVFASDVVDRYANHIYYGSGATGMALVVIDGNQ
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCEEEEEECCCH
RVFRSFGETRPGNNQHPQLDSVIRIASLSKLMTSEMLVKLLDQGVVKLNDPLSKYAPPGA
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHCCCCC
RVPDWQGKPITLVNLATHTSALPREQPGGAAHRPVFVWPTRQQRWNWLSTATLKAAPGSQ
CCCCCCCCCEEEEEECHHCCCCCCCCCCCCCCCCEEEECCHHHHCCCHHHEEEECCCCCH
AAYSNLAFDLLADALATAAGKPYPQLFEEQITRPLGMKDTTFTPSPDQCQRLMIPEKGAS
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHEEECCCCCCC
PCNNTLAAIGSGGVYSTPGDMMRWMQQFLSSDFYTRSQQADRMQTLIYQRNQLTRVIGMD
CCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPGRADALGLGWVYMKPKNGHPGIIQKTGGGGGFITYMAMNPQANVGAFVVVTRSPLTRF
CCCCCCEEEEEEEEEECCCCCCCCEEECCCCCEEEEEEEECCCCCCCEEEEEECCHHHHH
NNMSDGINDLVSELSGAQPNMQTASQ
CCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]