| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is livF [H]
Identifier: 238893282
GI number: 238893282
Start: 1124404
End: 1125099
Strand: Reverse
Name: livF [H]
Synonym: KP1_1156
Alternate gene names: 238893282
Gene position: 1125099-1124404 (Counterclockwise)
Preceding gene: 238893283
Following gene: 238893281
Centisome position: 21.44
GC content: 61.35
Gene sequence:
>696_bases ATGCTTAACGCCCGGGAACTGAAGGTCTTTTACGGCGTGATCCAGGGTCTGAAGGGCGTCGATATCGATGTCTATGACCG GGAAATCGTCACCCTGATCGGCAGCAATGGCGCCGGTAAAACCTCCACCCTGAACGGGATCGTCAACCTGGTGCGCTCCA GTGGGCGCGTCAGCTTCCTCAACGACGATATCTCACGCAGCCAGACCCACCAGATCGTGCGTCGCGGGCTGGCGCTGGTG CCGGAGGGACGGCGCGTCTTTACCAACCTGACCATCGAAGAAAACCTGCGCATGGGCGCTTACAATAATCTCGCCGGCTA CGCCCGCCTGCGCGATCGCATGTACGCCCTCTTTCCGCGGCTCAAGGAGCGGCGCCATCAGATGGCGGGCACCATGAGCG GCGGCGAGCAGCAGATGCTGGCCATCGCCCGGGCGCTGATGAGCGAGCCGGTGTTATTGATGCTGGATGAACCGAGCCTC GGGCTGGCGCCGAAAATTGTCGGCGAGCTGTTCGGCATCATTAAGCAACTGCGCGAAGAGAATATGACGGTGCTGCTGGT GGAGCAGAATGCGACGGCCGCGCTGGCGATCGCCGATCGGGCGTATGTCCTGGAGAATGGCCGGATCACCTTGTCAGGCG CGGCGCGGGAGATGCTGACTAATCCGGAAATTAAGCGGATGTATCTGGGGGGATAG
Upstream 100 bases:
>100_bases GTGATGGTTCTGGAGTACGGTAAGCCGCTGTTCAGCGGCCTGATGGCCGAGGCGATCCAGCATCCGGACGTCATTTCCGC TTATCTGGGAGAAGCCAATT
Downstream 100 bases:
>100_bases GCATGGTCAAAACTGCCTGGGCTGCGGCGGCGCCTCCCGCGATGCCGCAACCTCAGGCAGTCTCTTGCTACACAAAGCAC ACCTCGTTCCAGTAGGCTTC
Product: ABC transport system ATP-binding component
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein F [H]
Number of amino acids: Translated: 231; Mature: 231
Protein sequence:
>231_residues MLNARELKVFYGVIQGLKGVDIDVYDREIVTLIGSNGAGKTSTLNGIVNLVRSSGRVSFLNDDISRSQTHQIVRRGLALV PEGRRVFTNLTIEENLRMGAYNNLAGYARLRDRMYALFPRLKERRHQMAGTMSGGEQQMLAIARALMSEPVLLMLDEPSL GLAPKIVGELFGIIKQLREENMTVLLVEQNATAALAIADRAYVLENGRITLSGAAREMLTNPEIKRMYLGG
Sequences:
>Translated_231_residues MLNARELKVFYGVIQGLKGVDIDVYDREIVTLIGSNGAGKTSTLNGIVNLVRSSGRVSFLNDDISRSQTHQIVRRGLALV PEGRRVFTNLTIEENLRMGAYNNLAGYARLRDRMYALFPRLKERRHQMAGTMSGGEQQMLAIARALMSEPVLLMLDEPSL GLAPKIVGELFGIIKQLREENMTVLLVEQNATAALAIADRAYVLENGRITLSGAAREMLTNPEIKRMYLGG >Mature_231_residues MLNARELKVFYGVIQGLKGVDIDVYDREIVTLIGSNGAGKTSTLNGIVNLVRSSGRVSFLNDDISRSQTHQIVRRGLALV PEGRRVFTNLTIEENLRMGAYNNLAGYARLRDRMYALFPRLKERRHQMAGTMSGGEQQMLAIARALMSEPVLLMLDEPSL GLAPKIVGELFGIIKQLREENMTVLLVEQNATAALAIADRAYVLENGRITLSGAAREMLTNPEIKRMYLGG
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI27436953, Length=214, Percent_Identity=27.5700934579439, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI27477115, Length=217, Percent_Identity=28.110599078341, Blast_Score=94, Evalue=7e-20, Organism=Homo sapiens, GI153792144, Length=207, Percent_Identity=27.536231884058, Blast_Score=94, Evalue=8e-20, Organism=Homo sapiens, GI47078218, Length=204, Percent_Identity=27.9411764705882, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI45446740, Length=204, Percent_Identity=27.9411764705882, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI105990541, Length=199, Percent_Identity=28.643216080402, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI30795238, Length=210, Percent_Identity=26.1904761904762, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI27881501, Length=210, Percent_Identity=26.1904761904762, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI116734710, Length=206, Percent_Identity=26.6990291262136, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI148612844, Length=239, Percent_Identity=28.0334728033473, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI255708477, Length=239, Percent_Identity=28.0334728033473, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI21536376, Length=214, Percent_Identity=27.1028037383178, Blast_Score=74, Evalue=8e-14, Organism=Homo sapiens, GI150417984, Length=235, Percent_Identity=28.5106382978723, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI31657092, Length=218, Percent_Identity=27.5229357798165, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI27262624, Length=205, Percent_Identity=23.9024390243902, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI27262626, Length=205, Percent_Identity=23.9024390243902, Blast_Score=70, Evalue=1e-12, Organism=Escherichia coli, GI87082268, Length=235, Percent_Identity=54.0425531914894, Blast_Score=239, Evalue=1e-64, Organism=Escherichia coli, GI1789864, Length=249, Percent_Identity=32.1285140562249, Blast_Score=123, Evalue=1e-29, Organism=Escherichia coli, GI1789593, Length=234, Percent_Identity=34.1880341880342, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1787089, Length=234, Percent_Identity=31.1965811965812, Blast_Score=105, Evalue=2e-24, Organism=Escherichia coli, GI1788225, Length=234, Percent_Identity=32.4786324786325, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1789672, Length=234, Percent_Identity=28.2051282051282, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1787029, Length=233, Percent_Identity=28.3261802575107, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI1787792, Length=229, Percent_Identity=28.82096069869, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI1786319, Length=215, Percent_Identity=30.2325581395349, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1790162, Length=254, Percent_Identity=26.3779527559055, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1790525, Length=231, Percent_Identity=29.004329004329, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1787370, Length=228, Percent_Identity=31.140350877193, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1788761, Length=227, Percent_Identity=28.1938325991189, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1786253, Length=207, Percent_Identity=29.4685990338164, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1786872, Length=237, Percent_Identity=26.5822784810127, Blast_Score=83, Evalue=1e-17, Organism=Escherichia coli, GI1787105, Length=211, Percent_Identity=29.8578199052133, Blast_Score=80, Evalue=8e-17, Organism=Escherichia coli, GI1788450, Length=240, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787712, Length=218, Percent_Identity=27.9816513761468, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1789991, Length=216, Percent_Identity=25.9259259259259, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1788472, Length=208, Percent_Identity=26.9230769230769, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1788644, Length=249, Percent_Identity=29.3172690763052, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI87081782, Length=223, Percent_Identity=30.9417040358744, Blast_Score=78, Evalue=4e-16, Organism=Escherichia coli, GI48994943, Length=220, Percent_Identity=29.0909090909091, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1790190, Length=234, Percent_Identity=25.6410256410256, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1788210, Length=207, Percent_Identity=27.0531400966184, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI87082267, Length=222, Percent_Identity=26.5765765765766, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI87081709, Length=215, Percent_Identity=25.1162790697674, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI48995001, Length=242, Percent_Identity=25.6198347107438, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI48994997, Length=238, Percent_Identity=26.890756302521, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI87081791, Length=226, Percent_Identity=23.8938053097345, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI1787500, Length=234, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1786803, Length=235, Percent_Identity=24.6808510638298, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1790739, Length=226, Percent_Identity=27.4336283185841, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1790544, Length=245, Percent_Identity=25.3061224489796, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1789873, Length=188, Percent_Identity=26.5957446808511, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1790467, Length=217, Percent_Identity=25.8064516129032, Blast_Score=71, Evalue=5e-14, Organism=Escherichia coli, GI1786398, Length=227, Percent_Identity=27.3127753303965, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1789032, Length=221, Percent_Identity=27.1493212669683, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1788506, Length=246, Percent_Identity=22.3577235772358, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1786981, Length=217, Percent_Identity=33.6405529953917, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1788165, Length=236, Percent_Identity=27.9661016949153, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1789586, Length=215, Percent_Identity=27.4418604651163, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1788897, Length=198, Percent_Identity=24.2424242424242, Blast_Score=64, Evalue=6e-12, Organism=Escherichia coli, GI1787758, Length=212, Percent_Identity=23.5849056603774, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1787164, Length=197, Percent_Identity=27.4111675126904, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI48994883, Length=246, Percent_Identity=21.5447154471545, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17565586, Length=211, Percent_Identity=27.0142180094787, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI115533608, Length=200, Percent_Identity=28.5, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI25146777, Length=216, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI71983516, Length=220, Percent_Identity=23.1818181818182, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI71983510, Length=220, Percent_Identity=23.1818181818182, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI71983523, Length=220, Percent_Identity=23.1818181818182, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17510237, Length=211, Percent_Identity=22.2748815165877, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI193202349, Length=225, Percent_Identity=28.4444444444444, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI115532730, Length=197, Percent_Identity=30.4568527918782, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI71992285, Length=211, Percent_Identity=27.0142180094787, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17539902, Length=218, Percent_Identity=27.5229357798165, Blast_Score=64, Evalue=8e-11, Organism=Drosophila melanogaster, GI24666092, Length=214, Percent_Identity=25.7009345794392, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI221512771, Length=208, Percent_Identity=24.0384615384615, Blast_Score=80, Evalue=8e-16, Organism=Drosophila melanogaster, GI24643674, Length=216, Percent_Identity=24.0740740740741, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI28574744, Length=201, Percent_Identity=26.865671641791, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI116007328, Length=202, Percent_Identity=27.2277227722772, Blast_Score=72, Evalue=2e-13, Organism=Drosophila melanogaster, GI28574150, Length=202, Percent_Identity=27.2277227722772, Blast_Score=72, Evalue=2e-13, Organism=Drosophila melanogaster, GI85816269, Length=211, Percent_Identity=25.5924170616114, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24580553, Length=211, Percent_Identity=25.5924170616114, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI85724864, Length=211, Percent_Identity=25.5924170616114, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24580555, Length=211, Percent_Identity=25.5924170616114, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24581191, Length=214, Percent_Identity=26.6355140186916, Blast_Score=71, Evalue=5e-13, Organism=Drosophila melanogaster, GI24581189, Length=214, Percent_Identity=26.6355140186916, Blast_Score=71, Evalue=5e-13, Organism=Drosophila melanogaster, GI24581193, Length=214, Percent_Identity=26.6355140186916, Blast_Score=71, Evalue=5e-13, Organism=Drosophila melanogaster, GI24581195, Length=214, Percent_Identity=26.6355140186916, Blast_Score=71, Evalue=5e-13, Organism=Drosophila melanogaster, GI24648314, Length=218, Percent_Identity=23.8532110091743, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI28574533, Length=198, Percent_Identity=25.7575757575758, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI85724858, Length=196, Percent_Identity=27.5510204081633, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI85724856, Length=196, Percent_Identity=27.5510204081633, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI24580547, Length=196, Percent_Identity=27.5510204081633, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI24580551, Length=196, Percent_Identity=27.5510204081633, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI24580549, Length=196, Percent_Identity=27.5510204081633, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI24580545, Length=196, Percent_Identity=27.5510204081633, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 25563; Mature: 25563
Theoretical pI: Translated: 9.99; Mature: 9.99
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 4.8 %Met (Translated Protein) 4.8 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 4.8 %Met (Mature Protein) 4.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLNARELKVFYGVIQGLKGVDIDVYDREIVTLIGSNGAGKTSTLNGIVNLVRSSGRVSFL CCCHHHHHHHHHHHHCCCCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEE NDDISRSQTHQIVRRGLALVPEGRRVFTNLTIEENLRMGAYNNLAGYARLRDRMYALFPR CCCHHHHHHHHHHHCCCEECCCCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHH LKERRHQMAGTMSGGEQQMLAIARALMSEPVLLMLDEPSLGLAPKIVGELFGIIKQLREE HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHC NMTVLLVEQNATAALAIADRAYVLENGRITLSGAAREMLTNPEIKRMYLGG CCEEEEEECCCCEEEEEECCEEEEECCEEEECCHHHHHHCCCCHHEEECCC >Mature Secondary Structure MLNARELKVFYGVIQGLKGVDIDVYDREIVTLIGSNGAGKTSTLNGIVNLVRSSGRVSFL CCCHHHHHHHHHHHHCCCCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEE NDDISRSQTHQIVRRGLALVPEGRRVFTNLTIEENLRMGAYNNLAGYARLRDRMYALFPR CCCHHHHHHHHHHHCCCEECCCCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHH LKERRHQMAGTMSGGEQQMLAIARALMSEPVLLMLDEPSLGLAPKIVGELFGIIKQLREE HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHC NMTVLLVEQNATAALAIADRAYVLENGRITLSGAAREMLTNPEIKRMYLGG CCEEEEEECCCCEEEEEECCEEEEECCEEEECCHHHHHHCCCCHHEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2195019; 8041620; 9278503 [H]