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The map label for this gene is hisJ [H]

Identifier: 238893281

GI number: 238893281

Start: 1122972

End: 1123823

Strand: Reverse

Name: hisJ [H]

Synonym: KP1_1154

Alternate gene names: 238893281

Gene position: 1123823-1122972 (Counterclockwise)

Preceding gene: 238893282

Following gene: 238893280

Centisome position: 21.41

GC content: 59.86

Gene sequence:

>852_bases
GTGATGTCCACAAAACAAAACAGGGATTCAGGGGAAAAAACTATGCGCAATAAAACCACAAAAATCGCACTGGCGCTGGG
TATGCTGCTGCTCGCCTCGCAGGCACAGGCGGACCAGCTGGCTGACATCAAAGCCGCCGGCGTCGTAAAAGTCGCCACCT
TCGACGCCAACCCGCCGTTCGGCTCCGTGGACGCCAAAACCCACCATATCGTCGGCTACGACGTCGACTTTGCCCAGGCG
CTGGCGAAAGCGCTCGGCGTCAAACTCGAGCTGGTGGCCACCAACCCGGCCAACCGTATTCCGCTGCTGCAGTCCGGCAA
AGCCGACCTGATCGTCGCCGACATTACCATCACCCCGGAGCGGGCCCAGGTTATTGATTTCTCAACGCCGTATTTCGTCA
CCGGCCAGCAGTTCCTCGTGCCGGCCGGCTCTCCGGATAAGCTCGATGAGTACAGCAAAGCGCGCATCGGCGCGGTGAAA
GGCACCACCGGCGAACAGGCCCTGCACCAGCGTTTCCCGCAGGCTCGCGTCCTCTCCTATGACGATATTCCGCTGGCCCT
GACCGCCCTGCGCAACGGCAACGTCCAGGCCATCACTCAGGACAGCACCATCCTCGCCGGTCTGCTGGCGGAAGCGCCGG
ATAAAGCCAAGTTTAAAATTCTGCCCGACCTGCTCAGCAAAGAAGAGATTGGCGTGGGCGTGAAGAAAGGCGAACCGGCC
CTGCTGAAGGCCGTCAACGATGAGCTGGTGAAGCTGGAGAAAACCGGCGAAGCCGCGAAAATCTATGATGTCTGGTTTGG
CCCTGCCACTAAAACGCCGCAGCCGCGCGCCTTTACCATAGAAGCGAAATAA

Upstream 100 bases:

>100_bases
GCCAGCGACGCATAAAGAATACCCATAGGTTTGTTAAGTTCTTTTTGGTTATAGATAAGAATTTTTTCTTCTTTGCCGCC
GACGGGCAATTTGTGGGAGC

Downstream 100 bases:

>100_bases
TATGTTCTCGGGTTTACTCTCCCACTCCGCGGCTCCGGCCGCGGATTTTTCACGTCTGCAGCGCGCCAGCATTACGTTCC
GTGATGTGGCCAAGCGCTAC

Product: cysteine transport system periplasmic binding component

Products: NA

Alternate protein names: HBP [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MMSTKQNRDSGEKTMRNKTTKIALALGMLLLASQAQADQLADIKAAGVVKVATFDANPPFGSVDAKTHHIVGYDVDFAQA
LAKALGVKLELVATNPANRIPLLQSGKADLIVADITITPERAQVIDFSTPYFVTGQQFLVPAGSPDKLDEYSKARIGAVK
GTTGEQALHQRFPQARVLSYDDIPLALTALRNGNVQAITQDSTILAGLLAEAPDKAKFKILPDLLSKEEIGVGVKKGEPA
LLKAVNDELVKLEKTGEAAKIYDVWFGPATKTPQPRAFTIEAK

Sequences:

>Translated_283_residues
MMSTKQNRDSGEKTMRNKTTKIALALGMLLLASQAQADQLADIKAAGVVKVATFDANPPFGSVDAKTHHIVGYDVDFAQA
LAKALGVKLELVATNPANRIPLLQSGKADLIVADITITPERAQVIDFSTPYFVTGQQFLVPAGSPDKLDEYSKARIGAVK
GTTGEQALHQRFPQARVLSYDDIPLALTALRNGNVQAITQDSTILAGLLAEAPDKAKFKILPDLLSKEEIGVGVKKGEPA
LLKAVNDELVKLEKTGEAAKIYDVWFGPATKTPQPRAFTIEAK
>Mature_283_residues
MMSTKQNRDSGEKTMRNKTTKIALALGMLLLASQAQADQLADIKAAGVVKVATFDANPPFGSVDAKTHHIVGYDVDFAQA
LAKALGVKLELVATNPANRIPLLQSGKADLIVADITITPERAQVIDFSTPYFVTGQQFLVPAGSPDKLDEYSKARIGAVK
GTTGEQALHQRFPQARVLSYDDIPLALTALRNGNVQAITQDSTILAGLLAEAPDKAKFKILPDLLSKEEIGVGVKKGEPA
LLKAVNDELVKLEKTGEAAKIYDVWFGPATKTPQPRAFTIEAK

Specific function: Component of the high-affinity histidine permease, a binding-protein-dependent transport system. The other components are proteins hisQ, hisM, and hisP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=249, Percent_Identity=33.3333333333333, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787088, Length=227, Percent_Identity=29.0748898678414, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787085, Length=213, Percent_Identity=30.0469483568075, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786876, Length=250, Percent_Identity=29.2, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787031, Length=203, Percent_Identity=32.0197044334975, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788649, Length=227, Percent_Identity=27.3127753303965, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788648, Length=231, Percent_Identity=25.1082251082251, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 30316; Mature: 30316

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSTKQNRDSGEKTMRNKTTKIALALGMLLLASQAQADQLADIKAAGVVKVATFDANPPF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHCCEEEEEEECCCCCC
GSVDAKTHHIVGYDVDFAQALAKALGVKLELVATNPANRIPLLQSGKADLIVADITITPE
CCCCCCEEEEEEECCHHHHHHHHHHCCEEEEEECCCCCCCCEEECCCCCEEEEEEEECCC
RAQVIDFSTPYFVTGQQFLVPAGSPDKLDEYSKARIGAVKGTTGEQALHQRFPQARVLSY
CCEEEECCCCEEECCCEEEEECCCCHHHHHHHHHHEEEECCCCHHHHHHHHCCCCEEEEE
DDIPLALTALRNGNVQAITQDSTILAGLLAEAPDKAKFKILPDLLSKEEIGVGVKKGEPA
CCCCEEEEEECCCCEEEEECCCHHHHHHHHCCCCCCEEEECHHHHCHHHHCCCCCCCCCH
LLKAVNDELVKLEKTGEAAKIYDVWFGPATKTPQPRAFTIEAK
HHHHHCHHHEEEECCCCEEEEEEEEECCCCCCCCCCEEEEECC
>Mature Secondary Structure
MMSTKQNRDSGEKTMRNKTTKIALALGMLLLASQAQADQLADIKAAGVVKVATFDANPPF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHCCEEEEEEECCCCCC
GSVDAKTHHIVGYDVDFAQALAKALGVKLELVATNPANRIPLLQSGKADLIVADITITPE
CCCCCCEEEEEEECCHHHHHHHHHHCCEEEEEECCCCCCCCEEECCCCCEEEEEEEECCC
RAQVIDFSTPYFVTGQQFLVPAGSPDKLDEYSKARIGAVKGTTGEQALHQRFPQARVLSY
CCEEEECCCCEEECCCEEEEECCCCHHHHHHHHHHEEEECCCCHHHHHHHHCCCCEEEEE
DDIPLALTALRNGNVQAITQDSTILAGLLAEAPDKAKFKILPDLLSKEEIGVGVKKGEPA
CCCCEEEEEECCCCEEEEECCCHHHHHHHHCCCCCCEEEECHHHHCHHHHCCCCCCCCCH
LLKAVNDELVKLEKTGEAAKIYDVWFGPATKTPQPRAFTIEAK
HHHHHCHHHEEEECCCCEEEEEEEEECCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1448614 [H]