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The map label for this gene is phnD [H]

Identifier: 238893269

GI number: 238893269

Start: 1111274

End: 1112200

Strand: Reverse

Name: phnD [H]

Synonym: KP1_1142

Alternate gene names: 238893269

Gene position: 1112200-1111274 (Counterclockwise)

Preceding gene: 238893270

Following gene: 238893268

Centisome position: 21.19

GC content: 57.28

Gene sequence:

>927_bases
ATGACTGGCGCAGTTCGTTTATCCGCAATGGTCGCGGGCATGATGATGGCATGGCAGGCAGCGGCGGCGCAGCCGAAAGA
GCTCAATCTGGGCATTCTCGGCGGCCAGAACGCCACCCAGCAAATCGGCGATAACCAGTGCGTGAAAGCCTTCCTCGATA
AAGAGCTGAACGTGGATACCAAACTGCGCAACTCTTCCGACTATTCCGGGGTGATCCAGGGCCTGCTGGGGGGCAAAGTC
GACGTGGTGCTGAGCATGTCCCCCTCCTCCTACGCCTCGGTTTATCTCAATAATCCGAAAGCGGTGGATATCGTCGGCAT
CGCCGTGGACGACAAAGATCAGTCTCGCGGCTATCACTCGGTGGTGATCGTCAAAGCCGACTCCCCGTACAAAACGCTGG
ACGATTTAAAAGGCAAAGCCTTCGGCTTCGCCGATCCGGATTCCACTTCCGGGTATCTGATCCCTAACCATGCGTTTAAA
GAAAAATTTGGCGGTAACGCCGACAACAAATACAACAACACCTTCTCCAGCGTCACCTTCTCCGGCGGCCATGAGCAGGA
CATCCTCGGCGTGCTGAATGGCCAGTTCGCGGGCGCGGTCACGTGGGCCTCGATGGTTGGCGATTACAACACCGGCTACA
CTACCGGCGCGTTCAACCGCCTGATTCGCATGGATCATCCGGATCTGATGAAGCAGATCCGCATTATCTGGCAATCGCCG
CTGATCCCGAACGGCCCGATCCTGGTGAGCAATGCGCTGCCGGCGGACTTTAAGGCGAAGGTCGTGGCGGCAGTGAAAAA
GCTGGACACCGAGGATCACGCCTGCTTTATCAAAGCGATGGGCGGTACTCAGCACATCGGCCCGGGCAGCGTGGCTGACT
TCCAGCAGATTATTGATATGAAACGCGAGCTGGTGAGCGCGCGTTAA

Upstream 100 bases:

>100_bases
CCCTCCCGGCTGACGCAGGATGTGCTGCAGCGGCTGTACGGCGATGAAGTTAGCCAATTGCATTAATTTCACTCACACGG
GCAACATAATGAAAAAATAT

Downstream 100 bases:

>100_bases
TCCTGCCTCAACGCCGCCTGCTTGCCCCAGGGTAAGCGGCGGCGCTACGTTGAAGATCCCCGACGCATGAAGACAACCCA
CACCGAATTTGAACGCTATT

Product: phosphonate ABC transport system periplasmic phosphonate-binding component

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTGAVRLSAMVAGMMMAWQAAAAQPKELNLGILGGQNATQQIGDNQCVKAFLDKELNVDTKLRNSSDYSGVIQGLLGGKV
DVVLSMSPSSYASVYLNNPKAVDIVGIAVDDKDQSRGYHSVVIVKADSPYKTLDDLKGKAFGFADPDSTSGYLIPNHAFK
EKFGGNADNKYNNTFSSVTFSGGHEQDILGVLNGQFAGAVTWASMVGDYNTGYTTGAFNRLIRMDHPDLMKQIRIIWQSP
LIPNGPILVSNALPADFKAKVVAAVKKLDTEDHACFIKAMGGTQHIGPGSVADFQQIIDMKRELVSAR

Sequences:

>Translated_308_residues
MTGAVRLSAMVAGMMMAWQAAAAQPKELNLGILGGQNATQQIGDNQCVKAFLDKELNVDTKLRNSSDYSGVIQGLLGGKV
DVVLSMSPSSYASVYLNNPKAVDIVGIAVDDKDQSRGYHSVVIVKADSPYKTLDDLKGKAFGFADPDSTSGYLIPNHAFK
EKFGGNADNKYNNTFSSVTFSGGHEQDILGVLNGQFAGAVTWASMVGDYNTGYTTGAFNRLIRMDHPDLMKQIRIIWQSP
LIPNGPILVSNALPADFKAKVVAAVKKLDTEDHACFIKAMGGTQHIGPGSVADFQQIIDMKRELVSAR
>Mature_307_residues
TGAVRLSAMVAGMMMAWQAAAAQPKELNLGILGGQNATQQIGDNQCVKAFLDKELNVDTKLRNSSDYSGVIQGLLGGKVD
VVLSMSPSSYASVYLNNPKAVDIVGIAVDDKDQSRGYHSVVIVKADSPYKTLDDLKGKAFGFADPDSTSGYLIPNHAFKE
KFGGNADNKYNNTFSSVTFSGGHEQDILGVLNGQFAGAVTWASMVGDYNTGYTTGAFNRLIRMDHPDLMKQIRIIWQSPL
IPNGPILVSNALPADFKAKVVAAVKKLDTEDHACFIKAMGGTQHIGPGSVADFQQIIDMKRELVSAR

Specific function: Part of the binding-protein-dependent transport system for alkylphosphonates [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790543, Length=247, Percent_Identity=31.5789473684211, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017797
- InterPro:   IPR005770 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 33052; Mature: 32921

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGAVRLSAMVAGMMMAWQAAAAQPKELNLGILGGQNATQQIGDNQCVKAFLDKELNVDT
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHCCHHHHHHHHCCCCCCCE
KLRNSSDYSGVIQGLLGGKVDVVLSMSPSSYASVYLNNPKAVDIVGIAVDDKDQSRGYHS
EECCCCCHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCEEEEEEEEECCCCCCCCCEE
VVIVKADSPYKTLDDLKGKAFGFADPDSTSGYLIPNHAFKEKFGGNADNKYNNTFSSVTF
EEEEECCCCCHHHHHCCCCEECCCCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCCEEEE
SGGHEQDILGVLNGQFAGAVTWASMVGDYNTGYTTGAFNRLIRMDHPDLMKQIRIIWQSP
CCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCC
LIPNGPILVSNALPADFKAKVVAAVKKLDTEDHACFIKAMGGTQHIGPGSVADFQQIIDM
CCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
KRELVSAR
HHHHHCCC
>Mature Secondary Structure 
TGAVRLSAMVAGMMMAWQAAAAQPKELNLGILGGQNATQQIGDNQCVKAFLDKELNVDT
CCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHCCHHHHHHHHCCCCCCCE
KLRNSSDYSGVIQGLLGGKVDVVLSMSPSSYASVYLNNPKAVDIVGIAVDDKDQSRGYHS
EECCCCCHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCEEEEEEEEECCCCCCCCCEE
VVIVKADSPYKTLDDLKGKAFGFADPDSTSGYLIPNHAFKEKFGGNADNKYNNTFSSVTF
EEEEECCCCCHHHHHCCCCEECCCCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCCEEEE
SGGHEQDILGVLNGQFAGAVTWASMVGDYNTGYTTGAFNRLIRMDHPDLMKQIRIIWQSP
CCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCC
LIPNGPILVSNALPADFKAKVVAAVKKLDTEDHACFIKAMGGTQHIGPGSVADFQQIIDM
CCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
KRELVSAR
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155230; 1840580; 7610040; 9278503 [H]