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The map label for this gene is dinB [H]

Identifier: 238893224

GI number: 238893224

Start: 1065968

End: 1067023

Strand: Direct

Name: dinB [H]

Synonym: KP1_1093

Alternate gene names: 238893224

Gene position: 1065968-1067023 (Clockwise)

Preceding gene: 238893222

Following gene: 238893225

Centisome position: 20.31

GC content: 58.14

Gene sequence:

>1056_bases
ATGCGTAAAATTATCCATGTCGATATGGACTGTTTCTTTGCGGCGGTGGAGATGCGCGACAACCCAGCGTTGTGCGATAT
ACCCCTCGCGATAGGCGGCAGTCGGGTACAACGTGGCGTGATTAGTACCGCGAACTATCCTGCGCGTAAGTTTGGCGTGC
GCAGCGCCATGCCGACGGCGACGGCGCTCAAGCTGTGCCCGCATCTCACGCTGCTTCCCGGCCGCTTCGATGCCTACAAA
GAAGCCTCGAACCATATCCGTGAAATTTTCTCCCGCTATACCTCGCGCATTGAGCCGCTGTCGCTGGATGAAGCCTATCT
TGACGTCAGCGACAGCGAGCATTGTCACGGGTCAGCCACCCTGATAGCCCAGGAGATCCGCCAGACCATCGAACGGGAGC
TGCGCCTCACCGCCTCGGCGGGGGTGGCGCCGGTGAAGTTTCTCGCTAAAATCGCTTCAGATATGAATAAACCCAACGGC
CAGTTCGTTATCGCCCCCCATCAGGTGGCAGAGTTTGTGCGGGCGCTGCCGCTGGCGAAAATACCCGGCGTCGGGAAGGT
ATCGGCAGCGAAGCTGGAAAATATGGGCCTGCGAACCTGTGGCGATGTGCAGAACAGCGATCTGGCCATGCTGCTTAAGC
GCTTCGGTAAATTCGGGCGTATTCTGTGGGAGCGCAGCCACGGGATTGATGAGCGGGAAATTCATAACGATCGGCAGCGT
AAATCGGTGGGCGTGGAGCGCACCTTAGCGGAAGATATCCATGAATGGCCGGAGTGCGAAGCGATTATCGAAAACCTCTA
TCCCGAGCTGGAGAGGCGACTGGCGAAGGTCAAACCTGATCTGCTGATCGCCCGTCAGGGCATTAAACTGAAATTCAATG
ATTTCCAGCTGACCACCCAGGAGCACGTCTGGCCCCGGCTGAACAAAGAGGATCTGATCGCCACCGCGCACAAAGCCTGG
GATGAGCGCCGCGGCGGACGGGGCGTGCGCCTGGTTGGGCTCCACGTGACGTTGCTCGATCCGCAGCTGGAAAGGCAGCT
TTTATTAGGGATTTAG

Upstream 100 bases:

>100_bases
TTTATGTTTTAACCGCTTTTTTAGCCGATGAAATAAAAAAAGCATAAAATTCGCATCTGATTTTGCTATGCTGTATGGGT
ATACAGTGTTGAGTCTGACG

Downstream 100 bases:

>100_bases
CCATGCATATTCGTGCTTACCGCGACAGCGATTTGCCACTGCTCTGCCAGATCTTTCTGCGCGCGGTGCGGGAAACCGCC
AGTCGGGACTATACCCCGGG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MRKIIHVDMDCFFAAVEMRDNPALCDIPLAIGGSRVQRGVISTANYPARKFGVRSAMPTATALKLCPHLTLLPGRFDAYK
EASNHIREIFSRYTSRIEPLSLDEAYLDVSDSEHCHGSATLIAQEIRQTIERELRLTASAGVAPVKFLAKIASDMNKPNG
QFVIAPHQVAEFVRALPLAKIPGVGKVSAAKLENMGLRTCGDVQNSDLAMLLKRFGKFGRILWERSHGIDEREIHNDRQR
KSVGVERTLAEDIHEWPECEAIIENLYPELERRLAKVKPDLLIARQGIKLKFNDFQLTTQEHVWPRLNKEDLIATAHKAW
DERRGGRGVRLVGLHVTLLDPQLERQLLLGI

Sequences:

>Translated_351_residues
MRKIIHVDMDCFFAAVEMRDNPALCDIPLAIGGSRVQRGVISTANYPARKFGVRSAMPTATALKLCPHLTLLPGRFDAYK
EASNHIREIFSRYTSRIEPLSLDEAYLDVSDSEHCHGSATLIAQEIRQTIERELRLTASAGVAPVKFLAKIASDMNKPNG
QFVIAPHQVAEFVRALPLAKIPGVGKVSAAKLENMGLRTCGDVQNSDLAMLLKRFGKFGRILWERSHGIDEREIHNDRQR
KSVGVERTLAEDIHEWPECEAIIENLYPELERRLAKVKPDLLIARQGIKLKFNDFQLTTQEHVWPRLNKEDLIATAHKAW
DERRGGRGVRLVGLHVTLLDPQLERQLLLGI
>Mature_351_residues
MRKIIHVDMDCFFAAVEMRDNPALCDIPLAIGGSRVQRGVISTANYPARKFGVRSAMPTATALKLCPHLTLLPGRFDAYK
EASNHIREIFSRYTSRIEPLSLDEAYLDVSDSEHCHGSATLIAQEIRQTIERELRLTASAGVAPVKFLAKIASDMNKPNG
QFVIAPHQVAEFVRALPLAKIPGVGKVSAAKLENMGLRTCGDVQNSDLAMLLKRFGKFGRILWERSHGIDEREIHNDRQR
KSVGVERTLAEDIHEWPECEAIIENLYPELERRLAKVKPDLLIARQGIKLKFNDFQLTTQEHVWPRLNKEDLIATAHKAW
DERRGGRGVRLVGLHVTLLDPQLERQLLLGI

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=324, Percent_Identity=29.9382716049383, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI7706681, Length=325, Percent_Identity=29.8461538461538, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI154350220, Length=251, Percent_Identity=32.2709163346614, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=49.5327102803738, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI5729982, Length=119, Percent_Identity=41.1764705882353, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1786425, Length=351, Percent_Identity=87.7492877492877, Blast_Score=638, Evalue=0.0,
Organism=Escherichia coli, GI1787432, Length=217, Percent_Identity=25.8064516129032, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193205700, Length=409, Percent_Identity=30.5623471882641, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17537959, Length=289, Percent_Identity=29.757785467128, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=354, Percent_Identity=25.7062146892655, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI115534089, Length=351, Percent_Identity=24.2165242165242, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324921, Length=207, Percent_Identity=29.951690821256, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI19923006, Length=327, Percent_Identity=30.2752293577982, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=29.6819787985866, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=29.6819787985866, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24668444, Length=119, Percent_Identity=34.453781512605, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39526; Mature: 39526

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHVDMDCFFAAVEMRDNPALCDIPLAIGGSRVQRGVISTANYPARKFGVRSAMPTA
CCCEEEECHHHHHHHHEECCCCCEEEEEHHCCCHHHHHHHHCCCCCCHHHHCCHHCCCHH
TALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVSDSEHCHGSAT
HHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCHHH
LIAQEIRQTIERELRLTASAGVAPVKFLAKIASDMNKPNGQFVIAPHQVAEFVRALPLAK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHCCHHC
IPGVGKVSAAKLENMGLRTCGDVQNSDLAMLLKRFGKFGRILWERSHGIDEREIHNDRQR
CCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KSVGVERTLAEDIHEWPECEAIIENLYPELERRLAKVKPDLLIARQGIKLKFNDFQLTTQ
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEECCEEECHH
EHVWPRLNKEDLIATAHKAWDERRGGRGVRLVGLHVTLLDPQLERQLLLGI
HHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHCCC
>Mature Secondary Structure
MRKIIHVDMDCFFAAVEMRDNPALCDIPLAIGGSRVQRGVISTANYPARKFGVRSAMPTA
CCCEEEECHHHHHHHHEECCCCCEEEEEHHCCCHHHHHHHHCCCCCCHHHHCCHHCCCHH
TALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVSDSEHCHGSAT
HHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCHHH
LIAQEIRQTIERELRLTASAGVAPVKFLAKIASDMNKPNGQFVIAPHQVAEFVRALPLAK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHCCHHC
IPGVGKVSAAKLENMGLRTCGDVQNSDLAMLLKRFGKFGRILWERSHGIDEREIHNDRQR
CCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KSVGVERTLAEDIHEWPECEAIIENLYPELERRLAKVKPDLLIARQGIKLKFNDFQLTTQ
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEECCEEECHH
EHVWPRLNKEDLIATAHKAWDERRGGRGVRLVGLHVTLLDPQLERQLLLGI
HHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA