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The map label for this gene is cdaR [H]

Identifier: 238893160

GI number: 238893160

Start: 995917

End: 997074

Strand: Direct

Name: cdaR [H]

Synonym: KP1_1016

Alternate gene names: 238893160

Gene position: 995917-997074 (Clockwise)

Preceding gene: 238893159

Following gene: 238893165

Centisome position: 18.98

GC content: 61.31

Gene sequence:

>1158_bases
ATGGCTGGCTGGCATCTTGATACCAAAATGGCGCAGGATATTGTGGCGCGGACCATGCGCATCATCGATACCAATATCAA
CGTGATGGATGCCCGCGGGCGGATCATCGGCAGCGGCGATCGGGAAAGGATTGGTGAATTGCACGAAGGCGCGCTGCTGG
TCCTCTCCCAGGGGCGGGTGGTGGATATCGACGACGCGGTCGCTCGCCATCTGCACGGGGTTCGCCAGGGGATTAACCTG
CCGCTGCGCCTGGAGGGGGAGATCGTCGGGGTGATCGGCCTGACCGGCGAGCCGGAGTCGCTGCGAAAATATGGCGAGCT
GGTGTGCATGACAGCAGAGATGATGCTGGAGCAGTCGCGGCTGATGCATCTCCTGGCCCAGGACAGCCGTCTGCGCGAAG
AGCTGGTGATGAACCTGATTCAGGCGGAAGAGCATACCCCGGCGCTGAACGAATGGGCTCAGCGTTTAGGCATCGATCTC
AATCAGCCGCGCGTGGTGGCGATGATTGAGGTAGACAGCGGTCAGCTCGGCGTGGACAGCGCGATGGCGGAACTGCAACA
GTTACAGAACGCGCTGACCACCCCCGATCGCAATAATCTGGTGGCCATTGTCTCGCTCACGGAAATGGTGGTGCTGAAAC
CGGCGCTGAACAGCTTTGGCCGCTGGGACGCTGACGATCACGTCCGGCGCGTCGAGCAGCTTATCGCCAGGATGAAAGAG
AATGGCCAGCTGCGCTTTCGCGTGGCGCTGGGCAACTTCTTCACCGGCCCAGGAAGTATCGCCCGCTCTTACCGTACCGC
ACGGACGACGATGATGGTTGGCAAGCAGCGGATGCCGGAGAGCCGCAGTTATTTCTATCAGGATCTGATGCTGCCGGTGC
TGCTCGACAGCCTGCGCGGCGGCTGGCAGGCCAATGAGCTGGCCCGTCCGCTGGCGCGTTTGAAGGCCATGGACAACAAC
GGGCTGCTGCGGCGGACGCTGCAGGCGTGGTTTCGCCATAACGTGCAGCCGCTGGCGACGTCAAAGGCGCTGTTTATCCA
TCGCAATACGCTGGAGTACCGGTTGAACCGTATCTCGGAGCTGACCGGCCTGGATCTCGGTAGCTTTGACGACAGGCTGC
TGCTGTATATCGCGCTGCAGCTGGACGAACAACGCTAA

Upstream 100 bases:

>100_bases
CCCCCACAACTCCACATATCTCACCCCGGCTTAGTGCAAATGCACAATGCAGCGCGACGATGACTCTTTTATGCTGGTGC
CCAGCAAAGGGGAGGACTAC

Downstream 100 bases:

>100_bases
GACGTGGAGGCAAAAAAATGCCGGGCAGTGACGCGCCATACCCGGCCTGGACGATGCATGCTGTCTGGAGTGGATAGAGA
CCACCAGCCCGGCCAGGCAA

Product: carbohydrate diacid transcriptional activator CdaR

Products: NA

Alternate protein names: Sugar diacid regulator [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINL
PLRLEGEIVGVIGLTGEPESLRKYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEEHTPALNEWAQRLGIDL
NQPRVVAMIEVDSGQLGVDSAMAELQQLQNALTTPDRNNLVAIVSLTEMVVLKPALNSFGRWDADDHVRRVEQLIARMKE
NGQLRFRVALGNFFTGPGSIARSYRTARTTMMVGKQRMPESRSYFYQDLMLPVLLDSLRGGWQANELARPLARLKAMDNN
GLLRRTLQAWFRHNVQPLATSKALFIHRNTLEYRLNRISELTGLDLGSFDDRLLLYIALQLDEQR

Sequences:

>Translated_385_residues
MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINL
PLRLEGEIVGVIGLTGEPESLRKYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEEHTPALNEWAQRLGIDL
NQPRVVAMIEVDSGQLGVDSAMAELQQLQNALTTPDRNNLVAIVSLTEMVVLKPALNSFGRWDADDHVRRVEQLIARMKE
NGQLRFRVALGNFFTGPGSIARSYRTARTTMMVGKQRMPESRSYFYQDLMLPVLLDSLRGGWQANELARPLARLKAMDNN
GLLRRTLQAWFRHNVQPLATSKALFIHRNTLEYRLNRISELTGLDLGSFDDRLLLYIALQLDEQR
>Mature_384_residues
AGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINLP
LRLEGEIVGVIGLTGEPESLRKYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEEHTPALNEWAQRLGIDLN
QPRVVAMIEVDSGQLGVDSAMAELQQLQNALTTPDRNNLVAIVSLTEMVVLKPALNSFGRWDADDHVRRVEQLIARMKEN
GQLRFRVALGNFFTGPGSIARSYRTARTTMMVGKQRMPESRSYFYQDLMLPVLLDSLRGGWQANELARPLARLKAMDNNG
LLRRTLQAWFRHNVQPLATSKALFIHRNTLEYRLNRISELTGLDLGSFDDRLLLYIALQLDEQR

Specific function: Seems to regulate the expression of the operons for the enzymes involved in D-galactarate, D-glucarate and D-glycerate utilization [H]

COG id: COG3835

COG function: function code KT; Sugar diacid utilization regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CdaR family [H]

Homologues:

Organism=Escherichia coli, GI87081694, Length=385, Percent_Identity=94.2857142857143, Blast_Score=742, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008599 [H]

Pfam domain/function: PF05651 Diacid_rec [H]

EC number: NA

Molecular weight: Translated: 43560; Mature: 43429

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLSQGRV
CCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEECCCCHHHHHHHCCCEEEEEECCCE
VDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPESLRKYGELVCMTAEMMLEQSR
EECHHHHHHHHHHHHHCCCCCEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
LMHLLAQDSRLREELVMNLIQAEEHTPALNEWAQRLGIDLNQPRVVAMIEVDSGQLGVDS
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHH
AMAELQQLQNALTTPDRNNLVAIVSLTEMVVLKPALNSFGRWDADDHVRRVEQLIARMKE
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
NGQLRFRVALGNFFTGPGSIARSYRTARTTMMVGKQRMPESRSYFYQDLMLPVLLDSLRG
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
GWQANELARPLARLKAMDNNGLLRRTLQAWFRHNVQPLATSKALFIHRNTLEYRLNRISE
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHH
LTGLDLGSFDDRLLLYIALQLDEQR
HHCCCCCCCCCCEEEEEEEEECCCC
>Mature Secondary Structure 
AGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLSQGRV
CCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEECCCCHHHHHHHCCCEEEEEECCCE
VDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPESLRKYGELVCMTAEMMLEQSR
EECHHHHHHHHHHHHHCCCCCEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
LMHLLAQDSRLREELVMNLIQAEEHTPALNEWAQRLGIDLNQPRVVAMIEVDSGQLGVDS
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHH
AMAELQQLQNALTTPDRNNLVAIVSLTEMVVLKPALNSFGRWDADDHVRRVEQLIARMKE
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
NGQLRFRVALGNFFTGPGSIARSYRTARTTMMVGKQRMPESRSYFYQDLMLPVLLDSLRG
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
GWQANELARPLARLKAMDNNGLLRRTLQAWFRHNVQPLATSKALFIHRNTLEYRLNRISE
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHH
LTGLDLGSFDDRLLLYIALQLDEQR
HHCCCCCCCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10762278 [H]