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The map label for this gene is secM

Identifier: 238893077

GI number: 238893077

Start: 905022

End: 905450

Strand: Direct

Name: secM

Synonym: KP1_0921

Alternate gene names: 238893077

Gene position: 905022-905450 (Clockwise)

Preceding gene: 238893076

Following gene: 238893078

Centisome position: 17.24

GC content: 64.1

Gene sequence:

>429_bases
ATGGTCGCGGCCAGCCTCGGCCTGCCTGCGCTAAGCAACGGTCACGAGACCGCGGCGCCAGCGAAGGCGACCGCCAGCAA
TCACAATCCGAGCAAGGTTAATTTCTCTCAGCTGGCACTGCTGGAGACGAATCGCCGGCCCAGCTTTACCGTCGACTACT
GGCATCAGCACGCCATTCGCACCGTTATTCGTCATCTCTCCTTCGCCATGGCGCCGCAGGCGCTGCCGGTGGCGGAAGAA
ACTTCCCCGCTGCAGGCTCAGCATCTGGCGCTGCTCGACACCCTCAGCGCGCTGCTGACGCAGGACAGCACGCCGCCGGT
GGTGATCCGCCAGGCGGGTTACATCCCTTCTTCATATTCTGCCTTCCGCGTCAGCGCCTGGATAAGCCAGGTGGCGGGGA
TCCGCGCAGGGCCTCAACGTCTCAGCTGA

Upstream 100 bases:

>100_bases
ACGACGGGTCTAGCAAAGAAAGGTAATGAACGTGAGTGGATTGCTGACGCGCTGGCGACAGTTTGGCAGACGGTATTTTT
GGCCGCATCTCCTGTTGGGG

Downstream 100 bases:

>100_bases
AAATAACCACGGACCATCCTATTTTTTGTGACTCCGCACCGCGGGGCGTTTGAGATTTTATTATGCTTATCAAAATGTTA
ACCAAGGTTTTCGGCAGCCG

Product: SecA regulator SecM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MVAASLGLPALSNGHETAAPAKATASNHNPSKVNFSQLALLETNRRPSFTVDYWHQHAIRTVIRHLSFAMAPQALPVAEE
TSPLQAQHLALLDTLSALLTQDSTPPVVIRQAGYIPSSYSAFRVSAWISQVAGIRAGPQRLS

Sequences:

>Translated_142_residues
MVAASLGLPALSNGHETAAPAKATASNHNPSKVNFSQLALLETNRRPSFTVDYWHQHAIRTVIRHLSFAMAPQALPVAEE
TSPLQAQHLALLDTLSALLTQDSTPPVVIRQAGYIPSSYSAFRVSAWISQVAGIRAGPQRLS
>Mature_142_residues
MVAASLGLPALSNGHETAAPAKATASNHNPSKVNFSQLALLETNRRPSFTVDYWHQHAIRTVIRHLSFAMAPQALPVAEE
TSPLQAQHLALLDTLSALLTQDSTPPVVIRQAGYIPSSYSAFRVSAWISQVAGIRAGPQRLS

Specific function: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm, cytosol. Periplasm (By similarity). Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease (By similarity)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secM family

Homologues:

Organism=Escherichia coli, GI87081686, Length=149, Percent_Identity=70.4697986577181, Blast_Score=185, Evalue=9e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECM_KLEP7 (A6T4P0)

Other databases:

- EMBL:   CP000647
- RefSeq:   YP_001333791.1
- STRING:   A6T4P0
- GeneID:   5339023
- GenomeReviews:   CP000647_GR
- KEGG:   kpn:KPN_00101
- eggNOG:   NOG07544
- HOGENOM:   HBG416690
- OMA:   FAMAPQA
- ProtClustDB:   PRK02943
- GO:   GO:0005829
- HAMAP:   MF_01332
- InterPro:   IPR009502
- PIRSF:   PIRSF004572
- ProDom:   PD089227

Pfam domain/function: PF06558 SecM

EC number: NA

Molecular weight: Translated: 15247; Mature: 15247

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAASLGLPALSNGHETAAPAKATASNHNPSKVNFSQLALLETNRRPSFTVDYWHQHAIR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEECCCCCCEEHHHHHHHHHH
TVIRHLSFAMAPQALPVAEETSPLQAQHLALLDTLSALLTQDSTPPVVIRQAGYIPSSYS
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
AFRVSAWISQVAGIRAGPQRLS
HHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MVAASLGLPALSNGHETAAPAKATASNHNPSKVNFSQLALLETNRRPSFTVDYWHQHAIR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEECCCCCCEEHHHHHHHHHH
TVIRHLSFAMAPQALPVAEETSPLQAQHLALLDTLSALLTQDSTPPVVIRQAGYIPSSYS
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
AFRVSAWISQVAGIRAGPQRLS
HHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA