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The map label for this gene is ftsW [H]

Identifier: 238893069

GI number: 238893069

Start: 895530

End: 896804

Strand: Direct

Name: ftsW [H]

Synonym: KP1_0911

Alternate gene names: 238893069

Gene position: 895530-896804 (Clockwise)

Preceding gene: 238893068

Following gene: 238893070

Centisome position: 17.06

GC content: 57.8

Gene sequence:

>1275_bases
ATGCGTTTCTCTCTCCCACGCCTGAGAATGCCGCAGCTGAGCCTGCCTCGGCTGAGACTGCCGCGACTGCCGGGGATGTT
TATTTTCGCCTGGCTATTCGCTGCGCTGAAAGGCTGGGTGATGGGCTCGCGCCCGAAAGATAACGACAGTCTGGTGATGT
ATGACCGGATGCTGCTATGGCTGACCTTCGGCCTGGCGGCGATCGGCTTTATTATGGTGACCTCGGCGTCGATGCCGGTC
GGACAGCGCCTGGCGAACGATCCTTTCCTCTTCGCCAAGCGTGACGGCCTTTACATTGTGCTGGCCTTCGCGCTGGCGAT
GATTACGCTACGTCTGCCGATGGATTTCTGGCAGCGCCACAGTACCGCGATGCTGATCGCCTCGATCGTCATGCTGCTGA
TCGTACTGGTAGTAGGCAGCTCGGTAAACGGCGCATCGCGCTGGATAGCCCTTGGTCCGCTGCGTATTCAGCCGGCGGAG
TTCACCAAGCTGTCGCTGTTCTGCTACATCGCCAACTATCTGGTGCGTAAAGCCGACGAAGTGCGTAACAACCTGCGCGG
CTTCTTAAAACCGATGGGCGTGATTTTCGTACTGGCCATCCTGCTGCTGGCGCAGCCTGACCTCGGTACCGTGGTGGTCC
TGTTCGTCACCACGCTGGCGATGCTGTTTCTCGCCGGCGCGAAGCTGTGGCAGTTCATCGCCATTATCGGCATGGGTATT
TCGGCGGTGGTCCTGCTGATCCTCGCCGAACCATACCGTATTCGCCGCGTGACCTCCTTCTGGAACCCGTGGGAAGACCC
GTTCGGCAGCGGCTACCAGCTGACCCAGTCGCTGATGGCTTTCGGCCGAGGCGAGATGTGGGGGCAGGGCCTCGGCAACT
CGGTGCAAAAACTGGAGTATTTACCGGAAGCGCACACTGACTTTATCTTCGCCATTATCGGCGAAGAACTCGGTTATATC
GGTGTGGTACTGGCGCTTTTAATGGTATTCTTCGTCGCTTTCCGCGCCATGTCGATTGGCCGTAAAGCGCTGGAGATCGA
TCATCGCTTTTCCGGCTTCCTCGCCTGTGCGATTGGTATCTGGTTTAGCTTCCAGGCGTTAGTTAACGTCGGCGCGGCGG
CGGGGATGCTGCCGACGAAAGGTCTGACGCTGCCGCTGATCAGTTATGGTGGTTCCAGTCTGTTGATTATGTCGACGGCC
ATTATGTTGTTGTTGCGAATTGATTATGAAACGCGTCTGGAAAAAGCCCAGGCGTTTACACGGGGTGTGCGATGA

Upstream 100 bases:

>100_bases
ACATGGTGCTCCTGTCGCCGGCCTGCGCCAGCCTGGATCAGTTTAAGAACTTTGAACAACGGGGCGAGATGTTTGCCCGT
CTGGCGAAGGAGTTAGGTTG

Downstream 100 bases:

>100_bases
GCGGTCAGGAAAAGCGGTTGATGGTGATGGCGGGCGGTACCGGCGGGCATGTGTTCCCGGGACTGGCGGTCGCGCACCAT
TTAATGGACCAGGGCTGGCA

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MRFSLPRLRMPQLSLPRLRLPRLPGMFIFAWLFAALKGWVMGSRPKDNDSLVMYDRMLLWLTFGLAAIGFIMVTSASMPV
GQRLANDPFLFAKRDGLYIVLAFALAMITLRLPMDFWQRHSTAMLIASIVMLLIVLVVGSSVNGASRWIALGPLRIQPAE
FTKLSLFCYIANYLVRKADEVRNNLRGFLKPMGVIFVLAILLLAQPDLGTVVVLFVTTLAMLFLAGAKLWQFIAIIGMGI
SAVVLLILAEPYRIRRVTSFWNPWEDPFGSGYQLTQSLMAFGRGEMWGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYI
GVVLALLMVFFVAFRAMSIGRKALEIDHRFSGFLACAIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTA
IMLLLRIDYETRLEKAQAFTRGVR

Sequences:

>Translated_424_residues
MRFSLPRLRMPQLSLPRLRLPRLPGMFIFAWLFAALKGWVMGSRPKDNDSLVMYDRMLLWLTFGLAAIGFIMVTSASMPV
GQRLANDPFLFAKRDGLYIVLAFALAMITLRLPMDFWQRHSTAMLIASIVMLLIVLVVGSSVNGASRWIALGPLRIQPAE
FTKLSLFCYIANYLVRKADEVRNNLRGFLKPMGVIFVLAILLLAQPDLGTVVVLFVTTLAMLFLAGAKLWQFIAIIGMGI
SAVVLLILAEPYRIRRVTSFWNPWEDPFGSGYQLTQSLMAFGRGEMWGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYI
GVVLALLMVFFVAFRAMSIGRKALEIDHRFSGFLACAIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTA
IMLLLRIDYETRLEKAQAFTRGVR
>Mature_424_residues
MRFSLPRLRMPQLSLPRLRLPRLPGMFIFAWLFAALKGWVMGSRPKDNDSLVMYDRMLLWLTFGLAAIGFIMVTSASMPV
GQRLANDPFLFAKRDGLYIVLAFALAMITLRLPMDFWQRHSTAMLIASIVMLLIVLVVGSSVNGASRWIALGPLRIQPAE
FTKLSLFCYIANYLVRKADEVRNNLRGFLKPMGVIFVLAILLLAQPDLGTVVVLFVTTLAMLFLAGAKLWQFIAIIGMGI
SAVVLLILAEPYRIRRVTSFWNPWEDPFGSGYQLTQSLMAFGRGEMWGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYI
GVVLALLMVFFVAFRAMSIGRKALEIDHRFSGFLACAIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTA
IMLLLRIDYETRLEKAQAFTRGVR

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=413, Percent_Identity=89.1041162227603, Blast_Score=734, Evalue=0.0,
Organism=Escherichia coli, GI1786853, Length=319, Percent_Identity=30.7210031347962, Blast_Score=148, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 47209; Mature: 47209

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFSLPRLRMPQLSLPRLRLPRLPGMFIFAWLFAALKGWVMGSRPKDNDSLVMYDRMLLW
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHH
LTFGLAAIGFIMVTSASMPVGQRLANDPFLFAKRDGLYIVLAFALAMITLRLPMDFWQRH
HHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHH
STAMLIASIVMLLIVLVVGSSVNGASRWIALGPLRIQPAEFTKLSLFCYIANYLVRKADE
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHH
VRNNLRGFLKPMGVIFVLAILLLAQPDLGTVVVLFVTTLAMLFLAGAKLWQFIAIIGMGI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SAVVLLILAEPYRIRRVTSFWNPWEDPFGSGYQLTQSLMAFGRGEMWGQGLGNSVQKLEY
HHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCHHHHHHHH
LPEAHTDFIFAIIGEELGYIGVVLALLMVFFVAFRAMSIGRKALEIDHRFSGFLACAIGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
WFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIMLLLRIDYETRLEKAQAFT
HHHHHHHHHHHHHCCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RGVR
CCCC
>Mature Secondary Structure
MRFSLPRLRMPQLSLPRLRLPRLPGMFIFAWLFAALKGWVMGSRPKDNDSLVMYDRMLLW
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHH
LTFGLAAIGFIMVTSASMPVGQRLANDPFLFAKRDGLYIVLAFALAMITLRLPMDFWQRH
HHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHH
STAMLIASIVMLLIVLVVGSSVNGASRWIALGPLRIQPAEFTKLSLFCYIANYLVRKADE
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHH
VRNNLRGFLKPMGVIFVLAILLLAQPDLGTVVVLFVTTLAMLFLAGAKLWQFIAIIGMGI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SAVVLLILAEPYRIRRVTSFWNPWEDPFGSGYQLTQSLMAFGRGEMWGQGLGNSVQKLEY
HHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCHHHHHHHH
LPEAHTDFIFAIIGEELGYIGVVLALLMVFFVAFRAMSIGRKALEIDHRFSGFLACAIGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
WFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIMLLLRIDYETRLEKAQAFT
HHHHHHHHHHHHHCCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RGVR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]