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The map label for this gene is nudC [H]

Identifier: 238892471

GI number: 238892471

Start: 246226

End: 246999

Strand: Direct

Name: nudC [H]

Synonym: KP1_0236

Alternate gene names: 238892471

Gene position: 246226-246999 (Clockwise)

Preceding gene: 238892459

Following gene: 238892472

Centisome position: 4.69

GC content: 58.01

Gene sequence:

>774_bases
ATGGATCGTATTATTGAAAAATTAGATCGCGGCTGGTGGGTTGTCAGTCACGAACAAAAATTATGGTTGCCTGGTGGAGA
ATTACCACATGGCGAAGCGGTTAATTTCGATCTTGTCGGCCAGCATGCGCTGCATATTGGCGAGTGGCAGGGCGAGTCCG
TGTGGATGGTGCGCCAGGATCGTCGCCATGACATGGGATCGTTGCGCCAGGTGCTGGATCAGGATCCGGGACTCTTCCAG
CTGGCTGGGCGGGGGATCCAGCTCGCCGAATTTTATCGCTCGCATAAATTTTGCGGTTACTGCGGCCACCCGATGCATGC
CAGCAAAAGCGAATGGGCGATGCTGTGCAGCCACTGCCGTGAACGTTACTACCCGCAAATTGCCCCCTGCATTATCGTGG
CAATCCGTCGCGACGATGCGATCCTGCTGGCGCAACATACGCGCCATCGCAACGGCGTGCACACCGTGCTGGCCGGCTTT
GTCGAGGTCGGCGAAACCCTTGAGCAGGCGGTGGCTCGCGAGGTGATGGAGGAGAGCGGTATTCGGGTAAAAAACCTGCG
TTACGTGACCTCTCAGCCATGGCCGTTCCCGCAGTCGCTGATGACCGCCTTTATGGCGGATTACGCAGATGGCGAGATCG
TGGTCGACAAAAAAGAGTTACTGACCGCGGACTGGTATCGCTATGACGACCTGCCGCTTCTGCCGCCGCCGGGGACAGTG
GCGCGGCGGCTTATCGAAGATACCGTCGCGATGTGTCGGGCAGAGTTCGAGTGA

Upstream 100 bases:

>100_bases
TTAGCATGATTGACTCCGCTAGTTTTGATTTAAATCTGCTCACCAAAATGTAAATATAATGTTAACAACATGCCAGTGAA
GCAAAGGTAGTGCAATAGAT

Downstream 100 bases:

>100_bases
CATGTTACACTGGGCGTATCAACGCTAAAGGAATGTAAAAATGACCGAACTGAAGAACGATCGTTACCTGCGCGCGCTGC
TGCGTCAGCCGGTTGATGTC

Product: NADH pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MDRIIEKLDRGWWVVSHEQKLWLPGGELPHGEAVNFDLVGQHALHIGEWQGESVWMVRQDRRHDMGSLRQVLDQDPGLFQ
LAGRGIQLAEFYRSHKFCGYCGHPMHASKSEWAMLCSHCRERYYPQIAPCIIVAIRRDDAILLAQHTRHRNGVHTVLAGF
VEVGETLEQAVAREVMEESGIRVKNLRYVTSQPWPFPQSLMTAFMADYADGEIVVDKKELLTADWYRYDDLPLLPPPGTV
ARRLIEDTVAMCRAEFE

Sequences:

>Translated_257_residues
MDRIIEKLDRGWWVVSHEQKLWLPGGELPHGEAVNFDLVGQHALHIGEWQGESVWMVRQDRRHDMGSLRQVLDQDPGLFQ
LAGRGIQLAEFYRSHKFCGYCGHPMHASKSEWAMLCSHCRERYYPQIAPCIIVAIRRDDAILLAQHTRHRNGVHTVLAGF
VEVGETLEQAVAREVMEESGIRVKNLRYVTSQPWPFPQSLMTAFMADYADGEIVVDKKELLTADWYRYDDLPLLPPPGTV
ARRLIEDTVAMCRAEFE
>Mature_257_residues
MDRIIEKLDRGWWVVSHEQKLWLPGGELPHGEAVNFDLVGQHALHIGEWQGESVWMVRQDRRHDMGSLRQVLDQDPGLFQ
LAGRGIQLAEFYRSHKFCGYCGHPMHASKSEWAMLCSHCRERYYPQIAPCIIVAIRRDDAILLAQHTRHRNGVHTVLAGF
VEVGETLEQAVAREVMEESGIRVKNLRYVTSQPWPFPQSLMTAFMADYADGEIVVDKKELLTADWYRYDDLPLLPPPGTV
ARRLIEDTVAMCRAEFE

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI50593112, Length=165, Percent_Identity=36.3636363636364, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI13899267, Length=203, Percent_Identity=31.5270935960591, Blast_Score=105, Evalue=4e-23,
Organism=Escherichia coli, GI48994995, Length=257, Percent_Identity=87.9377431906615, Blast_Score=479, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI71986510, Length=143, Percent_Identity=36.3636363636364, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI212645999, Length=152, Percent_Identity=33.5526315789474, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6321371, Length=169, Percent_Identity=30.1775147928994, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 29549; Mature: 29549

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIIEKLDRGWWVVSHEQKLWLPGGELPHGEAVNFDLVGQHALHIGEWQGESVWMVRQD
CCHHHHHHCCCEEEEECCCEEECCCCCCCCCCCCCEEEECHHHHEEECCCCCEEEEEECH
RRHDMGSLRQVLDQDPGLFQLAGRGIQLAEFYRSHKFCGYCGHPMHASKSEWAMLCSHCR
HCCCHHHHHHHHCCCCCEEEHHCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
ERYYPQIAPCIIVAIRRDDAILLAQHTRHRNGVHTVLAGFVEVGETLEQAVAREVMEESG
HHCCCCCCCEEEEEEECCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IRVKNLRYVTSQPWPFPQSLMTAFMADYADGEIVVDKKELLTADWYRYDDLPLLPPPGTV
CEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHCEEECCCCCCCCCHHH
ARRLIEDTVAMCRAEFE
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDRIIEKLDRGWWVVSHEQKLWLPGGELPHGEAVNFDLVGQHALHIGEWQGESVWMVRQD
CCHHHHHHCCCEEEEECCCEEECCCCCCCCCCCCCEEEECHHHHEEECCCCCEEEEEECH
RRHDMGSLRQVLDQDPGLFQLAGRGIQLAEFYRSHKFCGYCGHPMHASKSEWAMLCSHCR
HCCCHHHHHHHHCCCCCEEEHHCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
ERYYPQIAPCIIVAIRRDDAILLAQHTRHRNGVHTVLAGFVEVGETLEQAVAREVMEESG
HHCCCCCCCEEEEEEECCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IRVKNLRYVTSQPWPFPQSLMTAFMADYADGEIVVDKKELLTADWYRYDDLPLLPPPGTV
CEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHCEEECCCCCCCCCHHH
ARRLIEDTVAMCRAEFE
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA