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The map label for this gene is rhtC [H]

Identifier: 238892419

GI number: 238892419

Start: 183545

End: 184165

Strand: Direct

Name: rhtC [H]

Synonym: KP1_0179

Alternate gene names: 238892419

Gene position: 183545-184165 (Clockwise)

Preceding gene: 238892418

Following gene: 238892422

Centisome position: 3.5

GC content: 61.03

Gene sequence:

>621_bases
ATGCTGATGCTTTTCCTCACCGTGGCGCTGGTGCATATCATTGCGCTGATGAGCCCGGGGCCGGACTTTTTCTTTGTCTC
ACAAACGGCCATCAGCCGCTCGCGCAGAGAGGCGATGATGGGTGTGCTGGGGATCACCTGCGGCGTCATGGTCTGGGCGG
GAGTGGCGCTGCTCGGCCTGAACCTGATCCTCGCCCGGATGGCGTGGCTGCATAACATTATTATGGTCGGCGGGGGCCTG
TATCTATGCTGGATGGGCTACCAGATGCTGCGTGGCGCGCTGAAAAAAGAGACGGTGGCCTCGGCGGAGCCGCAGGTGGA
GCTGGCCCGCAGCGGACGCAGCTTCGTGAAGGGATTGCTGACCAATCTGGCGAATCCGAAAGCGATTATCTACTTCGGCT
CAGTGTTTTCGCTGTTCGTGGGTGACAGCGTCGGCGCCGGCGCGCGCTGGGGCATTTTCCTGCTGATTATCGTTGAGACG
CTGGCCTGGTTTATGGTGGTTGCCAGCCTGTTCGCCCTGCCGGGGATGCGCCGCGGCTATCAGCGGATGGCGAAGTGGAT
CGACGGTATCGCCGGTACGCTGTTTGCGGGCTTCGGCATCCACCTGATTATCTCGCGTTAA

Upstream 100 bases:

>100_bases
GCGCTGATCCGGGCGCATGTTGATGGCGACGATGAGTAGTCAGCTGGCTGAAAAAGTGCCAGAATAGTTTCTCTCTTCAT
TATTTTCCTGCGAGTTAACT

Downstream 100 bases:

>100_bases
CCGGCATGCTGTTTCCCACCCGGTTGTTTCCGGGTGGGAAAGTATCAGTGGCGAAGCCGCTGCAGCTCGTCTTCAGACAG
ACCGGTCATTTCCATAATCG

Product: threonine efflux system

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MLMLFLTVALVHIIALMSPGPDFFFVSQTAISRSRREAMMGVLGITCGVMVWAGVALLGLNLILARMAWLHNIIMVGGGL
YLCWMGYQMLRGALKKETVASAEPQVELARSGRSFVKGLLTNLANPKAIIYFGSVFSLFVGDSVGAGARWGIFLLIIVET
LAWFMVVASLFALPGMRRGYQRMAKWIDGIAGTLFAGFGIHLIISR

Sequences:

>Translated_206_residues
MLMLFLTVALVHIIALMSPGPDFFFVSQTAISRSRREAMMGVLGITCGVMVWAGVALLGLNLILARMAWLHNIIMVGGGL
YLCWMGYQMLRGALKKETVASAEPQVELARSGRSFVKGLLTNLANPKAIIYFGSVFSLFVGDSVGAGARWGIFLLIIVET
LAWFMVVASLFALPGMRRGYQRMAKWIDGIAGTLFAGFGIHLIISR
>Mature_206_residues
MLMLFLTVALVHIIALMSPGPDFFFVSQTAISRSRREAMMGVLGITCGVMVWAGVALLGLNLILARMAWLHNIIMVGGGL
YLCWMGYQMLRGALKKETVASAEPQVELARSGRSFVKGLLTNLANPKAIIYFGSVFSLFVGDSVGAGARWGIFLLIIVET
LAWFMVVASLFALPGMRRGYQRMAKWIDGIAGTLFAGFGIHLIISR

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=206, Percent_Identity=86.8932038834951, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1786522, Length=201, Percent_Identity=27.8606965174129, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788099, Length=202, Percent_Identity=26.2376237623762, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22448; Mature: 22448

Theoretical pI: Translated: 10.79; Mature: 10.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMLFLTVALVHIIALMSPGPDFFFVSQTAISRSRREAMMGVLGITCGVMVWAGVALLGL
CHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLILARMAWLHNIIMVGGGLYLCWMGYQMLRGALKKETVASAEPQVELARSGRSFVKGLL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHH
TNLANPKAIIYFGSVFSLFVGDSVGAGARWGIFLLIIVETLAWFMVVASLFALPGMRRGY
HHCCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
QRMAKWIDGIAGTLFAGFGIHLIISR
HHHHHHHHHHHHHHHHHCHHEEEEEC
>Mature Secondary Structure
MLMLFLTVALVHIIALMSPGPDFFFVSQTAISRSRREAMMGVLGITCGVMVWAGVALLGL
CHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLILARMAWLHNIIMVGGGLYLCWMGYQMLRGALKKETVASAEPQVELARSGRSFVKGLL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHH
TNLANPKAIIYFGSVFSLFVGDSVGAGARWGIFLLIIVETLAWFMVVASLFALPGMRRGY
HHCCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
QRMAKWIDGIAGTLFAGFGIHLIISR
HHHHHHHHHHHHHHHHHCHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]