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The map label for this gene is hemX [H]

Identifier: 238892403

GI number: 238892403

Start: 165905

End: 167086

Strand: Reverse

Name: hemX [H]

Synonym: KP1_0161

Alternate gene names: 238892403

Gene position: 167086-165905 (Counterclockwise)

Preceding gene: 238892404

Following gene: 238892402

Centisome position: 3.18

GC content: 58.63

Gene sequence:

>1182_bases
ATGACGGAACAACAAAATCAATCCGCCGTGGTTGAAGAGACCAGGGAGGCCGTGGAGACCACACCACAGCCAGAGAACAC
TGAGAAGAAGAAGGCAGGCAATAAAACCAGCCTGGCGCTCAGCGCGATCGCTATCGCCATTGCGATAGCCGCCGGCATCG
GCCTGTATGGCCTGAACAAACAACAGGCCACGCGGCAAAACGCAACTACCTCTGAATTAGCAAGCCAGGTCGCGGCGCTG
CAAAAAGCGCAGGAAAATCAAAAAAGTGAACTGGAAGGTGTTATCAAACAGCAGGCCGACCAGCTAAACGAAGCCAAACA
CCAGCAGGAGACGCTGGCCAAACAGTTGGATGAGCTGCAGCAAAAAGTGGCGGTGATTTCCGGTAGCGATGCCAAAACCT
GGCTGCTGGCCCAGGCCGACTTCCTCGTCAAGCTGGCGGGACGTAAGCTGTGGAGCGATCAGGATGTCACCACCGCCGCC
GCGCTGCTGAAAAGCGCTGACGCCAGCCTCGCCGACATGAACGACCCAAGCCTCATCGGCGCCCGCCGGGCGATCACCGA
CGACATCGCCACCCTCTCCGCGGTAAGCCAGGTGGACTATGACGGCATGATCCTCAAGGTTAATCAGCTGGCGAACCAAA
TCGATAACCTGCGGCTGGCAGATAATAACGATGACGATTCGCCGATGGACGCTGATAGCGATGAGCTTTCCAGCTCTATC
AGCGAATGGCGCGTCAACCTGCAGAAAAGCTGGCAGAACTTTATGGACAGCTTTATCACCGTGCGCCGCCGCGATGAAAC
GGCGGTCCCGCTGCTGGCGCCGAATCAGGATATCTATCTGCGGGAAAATATTCGCTCTCGCCTGCTGGTCGCCGCGCAGG
CAGTTCCGCGCCATCAGGAAGAGACCTGGAAACAGTCGCTGGATAACGTCTCGACCTGGGTACGCGCCTATTATGATACC
GATGACGCCACCACCAAAGCCTTCCTCGACGAGGTGGATAAGCTCAGTCAGCAAAGCATTACCATGACGGTGCCGGAAAC
GCTGCAGAGTCAGGCGTTGCTGGAAAAACTGATGCAGACCCGAGTGCGCAACCTGATGGCGCAGCCTGCCGTTACCGCGG
GCGGCGCGCCTTCGCCCGCACCTGCTGCGCCGGCCGCCCCCGCTGCGCCGCAAGGAGAGTAA

Upstream 100 bases:

>100_bases
GGCCCGGGAACTGGGCTGGCAGGAGATTCAGGTTGCCGATAGCGCCGACAACGATGCGCTGCTACGCGCATTACAATAAC
TCTCAACATTGGAAGCCATA

Downstream 100 bases:

>100_bases
CGCATGCTGAAAATTCTTTTACTCTTCGCACTGTTGATCGCCGGGATCGTGCTCGGCCCGATGATCGCCGGGCATCAGGG
CTACGTCCTGATCCAGACCG

Product: putative uroporphyrinogen III C-methyltransferase

Products: NA

Alternate protein names: Urogen-III methylase; ORF X [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTEQQNQSAVVEETREAVETTPQPENTEKKKAGNKTSLALSAIAIAIAIAAGIGLYGLNKQQATRQNATTSELASQVAAL
QKAQENQKSELEGVIKQQADQLNEAKHQQETLAKQLDELQQKVAVISGSDAKTWLLAQADFLVKLAGRKLWSDQDVTTAA
ALLKSADASLADMNDPSLIGARRAITDDIATLSAVSQVDYDGMILKVNQLANQIDNLRLADNNDDDSPMDADSDELSSSI
SEWRVNLQKSWQNFMDSFITVRRRDETAVPLLAPNQDIYLRENIRSRLLVAAQAVPRHQEETWKQSLDNVSTWVRAYYDT
DDATTKAFLDEVDKLSQQSITMTVPETLQSQALLEKLMQTRVRNLMAQPAVTAGGAPSPAPAAPAAPAAPQGE

Sequences:

>Translated_393_residues
MTEQQNQSAVVEETREAVETTPQPENTEKKKAGNKTSLALSAIAIAIAIAAGIGLYGLNKQQATRQNATTSELASQVAAL
QKAQENQKSELEGVIKQQADQLNEAKHQQETLAKQLDELQQKVAVISGSDAKTWLLAQADFLVKLAGRKLWSDQDVTTAA
ALLKSADASLADMNDPSLIGARRAITDDIATLSAVSQVDYDGMILKVNQLANQIDNLRLADNNDDDSPMDADSDELSSSI
SEWRVNLQKSWQNFMDSFITVRRRDETAVPLLAPNQDIYLRENIRSRLLVAAQAVPRHQEETWKQSLDNVSTWVRAYYDT
DDATTKAFLDEVDKLSQQSITMTVPETLQSQALLEKLMQTRVRNLMAQPAVTAGGAPSPAPAAPAAPAAPQGE
>Mature_392_residues
TEQQNQSAVVEETREAVETTPQPENTEKKKAGNKTSLALSAIAIAIAIAAGIGLYGLNKQQATRQNATTSELASQVAALQ
KAQENQKSELEGVIKQQADQLNEAKHQQETLAKQLDELQQKVAVISGSDAKTWLLAQADFLVKLAGRKLWSDQDVTTAAA
LLKSADASLADMNDPSLIGARRAITDDIATLSAVSQVDYDGMILKVNQLANQIDNLRLADNNDDDSPMDADSDELSSSIS
EWRVNLQKSWQNFMDSFITVRRRDETAVPLLAPNQDIYLRENIRSRLLVAAQAVPRHQEETWKQSLDNVSTWVRAYYDTD
DATTKAFLDEVDKLSQQSITMTVPETLQSQALLEKLMQTRVRNLMAQPAVTAGGAPSPAPAAPAAPAAPQGE

Specific function: Siroheme and cobalamin biosynthesis. [C]

COG id: COG2959

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790235, Length=394, Percent_Identity=80.7106598984772, Blast_Score=607, Evalue=1e-175,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007470 [H]

Pfam domain/function: PF04375 HemX [H]

EC number: =2.1.1.107 [H]

Molecular weight: Translated: 42849; Mature: 42718

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQQNQSAVVEETREAVETTPQPENTEKKKAGNKTSLALSAIAIAIAIAAGIGLYGLNK
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCH
QQATRQNATTSELASQVAALQKAQENQKSELEGVIKQQADQLNEAKHQQETLAKQLDELQ
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKVAVISGSDAKTWLLAQADFLVKLAGRKLWSDQDVTTAAALLKSADASLADMNDPSLIG
HHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCCCHHHH
ARRAITDDIATLSAVSQVDYDGMILKVNQLANQIDNLRLADNNDDDSPMDADSDELSSSI
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCEECCCCCCCCCCCCCHHHHHHHH
SEWRVNLQKSWQNFMDSFITVRRRDETAVPLLAPNQDIYLRENIRSRLLVAAQAVPRHQE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEEHHHHHHHHHHHHHHCCCHHH
ETWKQSLDNVSTWVRAYYDTDDATTKAFLDEVDKLSQQSITMTVPETLQSQALLEKLMQT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHH
RVRNLMAQPAVTAGGAPSPAPAAPAAPAAPQGE
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEQQNQSAVVEETREAVETTPQPENTEKKKAGNKTSLALSAIAIAIAIAAGIGLYGLNK
CCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCH
QQATRQNATTSELASQVAALQKAQENQKSELEGVIKQQADQLNEAKHQQETLAKQLDELQ
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKVAVISGSDAKTWLLAQADFLVKLAGRKLWSDQDVTTAAALLKSADASLADMNDPSLIG
HHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCCCHHHH
ARRAITDDIATLSAVSQVDYDGMILKVNQLANQIDNLRLADNNDDDSPMDADSDELSSSI
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCEECCCCCCCCCCCCCHHHHHHHH
SEWRVNLQKSWQNFMDSFITVRRRDETAVPLLAPNQDIYLRENIRSRLLVAAQAVPRHQE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEEHHHHHHHHHHHHHHCCCHHH
ETWKQSLDNVSTWVRAYYDTDDATTKAFLDEVDKLSQQSITMTVPETLQSQALLEKLMQT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHH
RVRNLMAQPAVTAGGAPSPAPAAPAAPAAPQGE
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3062586; 3054815; 1379743; 9278503; 9298646 [H]