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The map label for this gene is hemY [H]

Identifier: 238892402

GI number: 238892402

Start: 164705

End: 165901

Strand: Reverse

Name: hemY [H]

Synonym: KP1_0160

Alternate gene names: 238892402

Gene position: 165901-164705 (Counterclockwise)

Preceding gene: 238892403

Following gene: 238892401

Centisome position: 3.16

GC content: 61.65

Gene sequence:

>1197_bases
ATGCTGAAAATTCTTTTACTCTTCGCACTGTTGATCGCCGGGATCGTGCTCGGCCCGATGATCGCCGGGCATCAGGGCTA
CGTCCTGATCCAGACCGATAATTACAATATCGAGACCAGCGTGACCGGGCTGGTGATCATCCTGATCCTCGCCATGGTGG
TGCTGTTCGCCATTGAATGGCTGCTGCGCCGCATTTTCCGCACCGGGGCGCATACGCGCGGCTGGTTTGTCGGCCGTAAA
CGCCGTCGCGCGCGTAAGCAAACCGAGCAGGCGCTGCTTAAGCTGGCGGAAGGTGATTACCAGCAGGTTGAGAAGCTGAT
GGCGAAAAATGCCGATCACGCCGAACAGCCGGTGGTGAACTATCTGCTGGCGGCGGAAGCGGCCCAGCAGCGCGGCGATG
AAGCGCGGGCCAACCAGCATCTGGAGCGCGCCACCGAGCTGGCGGGCGATGACCTGATCCCGGTGGAAATCACTCGCGTT
CGCCTGCAGCTGGCGCGTAATGAAAATCACGCTGCGCGCCATGGCATCGATAAGCTGCTGGAAATTACCCCGCGTCATCC
GGAAGTGCTGCGCCTCGCCGAACAGGCATACACCCGCACCGGCGCCTGGCAGTCGCTGCTGGACATCATTCCGTCGATGG
CGAAAGCTAACGTCGGCGATGAAGCGCACCGCGCGGCGCTGGAACAGCTGGCCTGGGTTGGCCTGATGGATAAAGCGCTG
GCCGATGGCGGCAGCGAAGGACTACGCGAATGGTGGCGCAACCAGAGCCGTAAAACGCGGGCGCTGGTGCCGCTGCAGGT
GGCGATGGCCGAGCGCCTCATCGAGAGCGACGATCACGATACCGCGCAGCAAATTATTATTGATGGTCTGAAGAAACAGT
ATGATGACCGTCTGGTGATGCCGATCCCGCGTCTGAAGACCAATAACCCGGAACAGCTGGAGAAAGTGCTGCGCCAGCAG
ATCAAAGCCGTTGGCGACCGTCCGCTGCTGTGGAGCACCCTGGGCCAGTCGCTGATGCGGCACGGCGAATGGCAGGAGGC
CAGCATCGCCTTCCGCGCCGCGCTTAAGCAGCGTCCGGATGCCTTTGATTACGCCTGGCTGGCGGATGCCCTGGACCGCC
TGCATCAGCCCGAAGAAGCCGCCGCTATGCGCCGCGATGGACTGCTGCTGACGCTGCAGAATAATCCTCAGCCATAA

Upstream 100 bases:

>100_bases
GCGCAACCTGATGGCGCAGCCTGCCGTTACCGCGGGCGGCGCGCCTTCGCCCGCACCTGCTGCGCCGGCCGCCCCCGCTG
CGCCGCAAGGAGAGTAACGC

Downstream 100 bases:

>100_bases
CCTGGCATGGCTATCGCCTCCTGCGGGGCGATAGCCCTTCTCCCCCGCCTTCGCATTGACGGATCCCTGAAAGAAAAAAA
CGCCTGCGCTGAAATCAGGG

Product: putative protoheme IX biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MLKILLLFALLIAGIVLGPMIAGHQGYVLIQTDNYNIETSVTGLVIILILAMVVLFAIEWLLRRIFRTGAHTRGWFVGRK
RRRARKQTEQALLKLAEGDYQQVEKLMAKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERATELAGDDLIPVEITRV
RLQLARNENHAARHGIDKLLEITPRHPEVLRLAEQAYTRTGAWQSLLDIIPSMAKANVGDEAHRAALEQLAWVGLMDKAL
ADGGSEGLREWWRNQSRKTRALVPLQVAMAERLIESDDHDTAQQIIIDGLKKQYDDRLVMPIPRLKTNNPEQLEKVLRQQ
IKAVGDRPLLWSTLGQSLMRHGEWQEASIAFRAALKQRPDAFDYAWLADALDRLHQPEEAAAMRRDGLLLTLQNNPQP

Sequences:

>Translated_398_residues
MLKILLLFALLIAGIVLGPMIAGHQGYVLIQTDNYNIETSVTGLVIILILAMVVLFAIEWLLRRIFRTGAHTRGWFVGRK
RRRARKQTEQALLKLAEGDYQQVEKLMAKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERATELAGDDLIPVEITRV
RLQLARNENHAARHGIDKLLEITPRHPEVLRLAEQAYTRTGAWQSLLDIIPSMAKANVGDEAHRAALEQLAWVGLMDKAL
ADGGSEGLREWWRNQSRKTRALVPLQVAMAERLIESDDHDTAQQIIIDGLKKQYDDRLVMPIPRLKTNNPEQLEKVLRQQ
IKAVGDRPLLWSTLGQSLMRHGEWQEASIAFRAALKQRPDAFDYAWLADALDRLHQPEEAAAMRRDGLLLTLQNNPQP
>Mature_398_residues
MLKILLLFALLIAGIVLGPMIAGHQGYVLIQTDNYNIETSVTGLVIILILAMVVLFAIEWLLRRIFRTGAHTRGWFVGRK
RRRARKQTEQALLKLAEGDYQQVEKLMAKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERATELAGDDLIPVEITRV
RLQLARNENHAARHGIDKLLEITPRHPEVLRLAEQAYTRTGAWQSLLDIIPSMAKANVGDEAHRAALEQLAWVGLMDKAL
ADGGSEGLREWWRNQSRKTRALVPLQVAMAERLIESDDHDTAQQIIIDGLKKQYDDRLVMPIPRLKTNNPEQLEKVLRQQ
IKAVGDRPLLWSTLGQSLMRHGEWQEASIAFRAALKQRPDAFDYAWLADALDRLHQPEEAAAMRRDGLLLTLQNNPQP

Specific function: Involved in a late step of protoheme IX synthesis [H]

COG id: COG3071

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1790234, Length=385, Percent_Identity=91.4285714285714, Blast_Score=720, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010817
- InterPro:   IPR005254
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR013105
- InterPro:   IPR019734 [H]

Pfam domain/function: PF07219 HemY_N; PF07719 TPR_2 [H]

EC number: NA

Molecular weight: Translated: 45022; Mature: 45022

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKILLLFALLIAGIVLGPMIAGHQGYVLIQTDNYNIETSVTGLVIILILAMVVLFAIEW
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLRRIFRTGAHTRGWFVGRKRRRARKQTEQALLKLAEGDYQQVEKLMAKNADHAEQPVVN
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHH
YLLAAEAAQQRGDEARANQHLERATELAGDDLIPVEITRVRLQLARNENHAARHGIDKLL
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
EITPRHPEVLRLAEQAYTRTGAWQSLLDIIPSMAKANVGDEAHRAALEQLAWVGLMDKAL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ADGGSEGLREWWRNQSRKTRALVPLQVAMAERLIESDDHDTAQQIIIDGLKKQYDDRLVM
HCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEC
PIPRLKTNNPEQLEKVLRQQIKAVGDRPLLWSTLGQSLMRHGEWQEASIAFRAALKQRPD
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
AFDYAWLADALDRLHQPEEAAAMRRDGLLLTLQNNPQP
CCHHHHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCCC
>Mature Secondary Structure
MLKILLLFALLIAGIVLGPMIAGHQGYVLIQTDNYNIETSVTGLVIILILAMVVLFAIEW
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLRRIFRTGAHTRGWFVGRKRRRARKQTEQALLKLAEGDYQQVEKLMAKNADHAEQPVVN
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHH
YLLAAEAAQQRGDEARANQHLERATELAGDDLIPVEITRVRLQLARNENHAARHGIDKLL
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
EITPRHPEVLRLAEQAYTRTGAWQSLLDIIPSMAKANVGDEAHRAALEQLAWVGLMDKAL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ADGGSEGLREWWRNQSRKTRALVPLQVAMAERLIESDDHDTAQQIIIDGLKKQYDDRLVM
HCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEC
PIPRLKTNNPEQLEKVLRQQIKAVGDRPLLWSTLGQSLMRHGEWQEASIAFRAALKQRPD
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
AFDYAWLADALDRLHQPEEAAAMRRDGLLLTLQNNPQP
CCHHHHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]