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The map label for this gene is nahR [H]

Identifier: 238892383

GI number: 238892383

Start: 142992

End: 143918

Strand: Reverse

Name: nahR [H]

Synonym: KP1_0141

Alternate gene names: 238892383

Gene position: 143918-142992 (Counterclockwise)

Preceding gene: 238892384

Following gene: 238892382

Centisome position: 2.74

GC content: 56.85

Gene sequence:

>927_bases
ATGCGGGAAGAACTGGATTTCAAATCGCTACGCTTTTTCTCTGCGCTCTACCGCTTGGGCAATGTTTCCCCAGCAGCGGA
CGCGCTCGATATCAGCCAGCCCACCGGCAGCCTTTTGCTGAAAAAACTACGAGATCATTTTGCTGACCCGCTGTTTGTCC
GGGTCGGGCAGCGGATGATCCCGACGCCGCGAGCGGACGCGATCGCCCCCACCATCTCGACTCTTCTCCAGCTTGCCGAT
AACGATTTAGCGGTCAAACCTGAATTTCTTCCCCAGCAGAGCCAGCGTAATTTTACGATCGGTATGACCGATATCAGCCA
AATGACGCTGCTGCCTTTATTGCAAATTGCGCTCCAGCAGCAGGCGGCGGACGGGATCACCTTTACGGTACAGAATCTGG
ATGAGCAGACCCTCAACGCCCTCGAATCCGGGAAATGCGATCTCGCGATCGGCTATCTGACGCAGCTTCCGGAAAGCGTC
TACCAGCAACATCTCTTCGATCAATCATATGTCTGCCTGGCTGCGGAAAACCATCCTCGCATTCGCGCACAGCTCCGCGC
CGAAGACTGGCGCCAGGAAAAGCATCTGGCGATCCGCGTGGAGGGGACTGCCCATGGCGATATGGATAAGCTGCTTGATG
AGCACCACATGCCCCGGCGCATTGCGCTAACGTTACCAAGTTTTTTAGGTACCGGTGAGCTGGTGGCCGAAAGCGATATG
ATTGCCGTCGTCCCGGAACAGGTGGCGCGGCATATCACCCGGCGCTATCCCTGCCGTAGCTGGCCGCTGCCTTTTCCCCT
CGCCAAAATCGCCATCCGTCAGGTCTGGCATCAGCGGCTGCACCGCGATCCCGGACATATCTGGCTACGCTCGCTGATCG
CTACGCTTGCCGATCCCGCACAGCAGAGTACTTCTATTAAAATCTAA

Upstream 100 bases:

>100_bases
GAGATGGTCGATCAGGAGTGTCAGTGGCAAAGCTACGTCCACTGGATACTTCGGGTCGCCAGCGGCGATACGCTGAAATA
ATATCCAGCCAGGAGGGCGG

Downstream 100 bases:

>100_bases
GTAACAAATTACGCCCGTGTATTGGTTTTATTAATAACCCCTATTACGTTTGGTTTATTGCTGGTAATACGTGAAAGCTT
TTATTCTCCTCGCATCAAGC

Product: putative LysR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MREELDFKSLRFFSALYRLGNVSPAADALDISQPTGSLLLKKLRDHFADPLFVRVGQRMIPTPRADAIAPTISTLLQLAD
NDLAVKPEFLPQQSQRNFTIGMTDISQMTLLPLLQIALQQQAADGITFTVQNLDEQTLNALESGKCDLAIGYLTQLPESV
YQQHLFDQSYVCLAAENHPRIRAQLRAEDWRQEKHLAIRVEGTAHGDMDKLLDEHHMPRRIALTLPSFLGTGELVAESDM
IAVVPEQVARHITRRYPCRSWPLPFPLAKIAIRQVWHQRLHRDPGHIWLRSLIATLADPAQQSTSIKI

Sequences:

>Translated_308_residues
MREELDFKSLRFFSALYRLGNVSPAADALDISQPTGSLLLKKLRDHFADPLFVRVGQRMIPTPRADAIAPTISTLLQLAD
NDLAVKPEFLPQQSQRNFTIGMTDISQMTLLPLLQIALQQQAADGITFTVQNLDEQTLNALESGKCDLAIGYLTQLPESV
YQQHLFDQSYVCLAAENHPRIRAQLRAEDWRQEKHLAIRVEGTAHGDMDKLLDEHHMPRRIALTLPSFLGTGELVAESDM
IAVVPEQVARHITRRYPCRSWPLPFPLAKIAIRQVWHQRLHRDPGHIWLRSLIATLADPAQQSTSIKI
>Mature_308_residues
MREELDFKSLRFFSALYRLGNVSPAADALDISQPTGSLLLKKLRDHFADPLFVRVGQRMIPTPRADAIAPTISTLLQLAD
NDLAVKPEFLPQQSQRNFTIGMTDISQMTLLPLLQIALQQQAADGITFTVQNLDEQTLNALESGKCDLAIGYLTQLPESV
YQQHLFDQSYVCLAAENHPRIRAQLRAEDWRQEKHLAIRVEGTAHGDMDKLLDEHHMPRRIALTLPSFLGTGELVAESDM
IAVVPEQVARHITRRYPCRSWPLPFPLAKIAIRQVWHQRLHRDPGHIWLRSLIATLADPAQQSTSIKI

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=300, Percent_Identity=25, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790147, Length=295, Percent_Identity=24.406779661017, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081766, Length=261, Percent_Identity=25.6704980842912, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786820, Length=283, Percent_Identity=22.2614840989399, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34813; Mature: 34813

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREELDFKSLRFFSALYRLGNVSPAADALDISQPTGSLLLKKLRDHFADPLFVRVGQRMI
CCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCHHHHHHCCHHC
PTPRADAIAPTISTLLQLADNDLAVKPEFLPQQSQRNFTIGMTDISQMTLLPLLQIALQQ
CCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
QAADGITFTVQNLDEQTLNALESGKCDLAIGYLTQLPESVYQQHLFDQSYVCLAAENHPR
HHCCCCEEEECCCCHHHHHHHHCCCCCEEHHHHHHCHHHHHHHHHCCCCEEEEEECCCCC
IRAQLRAEDWRQEKHLAIRVEGTAHGDMDKLLDEHHMPRRIALTLPSFLGTGELVAESDM
HHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEECHHHHCCCCHHCCCCE
IAVVPEQVARHITRRYPCRSWPLPFPLAKIAIRQVWHQRLHRDPGHIWLRSLIATLADPA
EEECHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCH
QQSTSIKI
HCCCCCCC
>Mature Secondary Structure
MREELDFKSLRFFSALYRLGNVSPAADALDISQPTGSLLLKKLRDHFADPLFVRVGQRMI
CCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCHHHHHHCCHHC
PTPRADAIAPTISTLLQLADNDLAVKPEFLPQQSQRNFTIGMTDISQMTLLPLLQIALQQ
CCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
QAADGITFTVQNLDEQTLNALESGKCDLAIGYLTQLPESVYQQHLFDQSYVCLAAENHPR
HHCCCCEEEECCCCHHHHHHHHCCCCCEEHHHHHHCHHHHHHHHHCCCCEEEEEECCCCC
IRAQLRAEDWRQEKHLAIRVEGTAHGDMDKLLDEHHMPRRIALTLPSFLGTGELVAESDM
HHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEECHHHHCCCCHHCCCCE
IAVVPEQVARHITRRYPCRSWPLPFPLAKIAIRQVWHQRLHRDPGHIWLRSLIATLADPA
EEECHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCH
QQSTSIKI
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]