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The map label for this gene is hdfR [H]

Identifier: 238892366

GI number: 238892366

Start: 125885

End: 126718

Strand: Reverse

Name: hdfR [H]

Synonym: KP1_0124

Alternate gene names: 238892366

Gene position: 126718-125885 (Counterclockwise)

Preceding gene: 238892368

Following gene: 238892362

Centisome position: 2.41

GC content: 50.84

Gene sequence:

>834_bases
GTGGAGAACGGTGTGGATACGGAATTGCTCAAAACTTTCCTGGAAGTGAGTAGAACTCGTCACTTTGGGCGAGCAGCTGA
GGCGCTTTACCTGACACAGTCAGCAGTCAGCTTTCGTATTCGTCAGCTGGAAAATCAACTTGGTGTGAATCTGTTCACCC
GTCATCGTAATAACATCCGCCTGACGACCGCCGGCGAAAAGCTCCTCCCCTATGCCGAAACGCTCATGAATACCTGGCAG
GCTGCGCGCAAGGAGGTGGCACACTCTTCGCGACATAATGAATTCTCCATTGGGGCCAGCGCCTCCCTGTGGGAATGTAT
GCTTAACAGCTGGCTCGGTACCCTCTACAGCGCACCTTACAATCTCCAGTTTGAAGCCCGTATCGCGCAGCGGCAGTCGT
TGGTTAAACAGCTTCACGAACGCCAGTTGGATCTGCTGATCACCACCGAATCGCCGAAGATGGATGAATTAAGCAGCCAG
CTGTTGGGTAATTTTACTCTTGCCCTGTATTGCGCATCGCCTGCAAAAAACAGAAATGAATTGAATTACTTGCGCCTTGA
ATGGGGGCCTGATTTTCAGCAAAACGAAGTGGGACTGATAGGAAGCGATGATGTTCCGCTGCTCACTACCTCTTCAGCTG
AACTGATCTATCAGCAATTATCGCGCCTGAACGGCTGCTGTTGGCTACCTGCTCGCTGGGCGAAAGAGAAGCATGGGTTA
CATACGGTCATGGACAGCGCTACGTTATCCCGTCCACTTTATGCGATCTGGTTACAAAATAGCGATAAGCAGGCGCAGAT
CCATGAGATCCTGAAAAACCCTATTCTGGAATAA

Upstream 100 bases:

>100_bases
CGCTCCTGATTCTTTGGCCGAGCTATTTATGGCGCGGAGTATTAGTTACGCTTGACAGAGCGTCAAACAAAACATTTAAA
TCATCACGACAAATAATTTT

Downstream 100 bases:

>100_bases
ACGCTACTCTCCATGGACGGAGATCAGCAAGGTATTTTCGTCGGGGATATTACCAATGGAGATTAGAGATAAAAAAAAAT
CCTTTGCCTGAGCAAAGGAT

Product: transcriptional regulator HdfR

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MENGVDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTTAGEKLLPYAETLMNTWQ
AARKEVAHSSRHNEFSIGASASLWECMLNSWLGTLYSAPYNLQFEARIAQRQSLVKQLHERQLDLLITTESPKMDELSSQ
LLGNFTLALYCASPAKNRNELNYLRLEWGPDFQQNEVGLIGSDDVPLLTTSSAELIYQQLSRLNGCCWLPARWAKEKHGL
HTVMDSATLSRPLYAIWLQNSDKQAQIHEILKNPILE

Sequences:

>Translated_277_residues
MENGVDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTTAGEKLLPYAETLMNTWQ
AARKEVAHSSRHNEFSIGASASLWECMLNSWLGTLYSAPYNLQFEARIAQRQSLVKQLHERQLDLLITTESPKMDELSSQ
LLGNFTLALYCASPAKNRNELNYLRLEWGPDFQQNEVGLIGSDDVPLLTTSSAELIYQQLSRLNGCCWLPARWAKEKHGL
HTVMDSATLSRPLYAIWLQNSDKQAQIHEILKNPILE
>Mature_277_residues
MENGVDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTTAGEKLLPYAETLMNTWQ
AARKEVAHSSRHNEFSIGASASLWECMLNSWLGTLYSAPYNLQFEARIAQRQSLVKQLHERQLDLLITTESPKMDELSSQ
LLGNFTLALYCASPAKNRNELNYLRLEWGPDFQQNEVGLIGSDDVPLLTTSSAELIYQQLSRLNGCCWLPARWAKEKHGL
HTVMDSATLSRPLYAIWLQNSDKQAQIHEILKNPILE

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994962, Length=276, Percent_Identity=81.1594202898551, Blast_Score=460, Evalue=1e-131,
Organism=Escherichia coli, GI1788626, Length=148, Percent_Identity=32.4324324324324, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI2367136, Length=64, Percent_Identity=48.4375, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790208, Length=207, Percent_Identity=25.6038647342995, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787601, Length=173, Percent_Identity=25.4335260115607, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31644; Mature: 31644

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENGVDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEE
LTTAGEKLLPYAETLMNTWQAARKEVAHSSRHNEFSIGASASLWECMLNSWLGTLYSAPY
EEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHCCCC
NLQFEARIAQRQSLVKQLHERQLDLLITTESPKMDELSSQLLGNFTLALYCASPAKNRNE
CEEHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCEEEEEEECCCCCCCCC
LNYLRLEWGPDFQQNEVGLIGSDDVPLLTTSSAELIYQQLSRLNGCCWLPARWAKEKHGL
CEEEEEEECCCCCCCCCCEECCCCCCEEECCHHHHHHHHHHHCCCEEECCHHHHHHHCCH
HTVMDSATLSRPLYAIWLQNSDKQAQIHEILKNPILE
HHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MENGVDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEE
LTTAGEKLLPYAETLMNTWQAARKEVAHSSRHNEFSIGASASLWECMLNSWLGTLYSAPY
EEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHCCCC
NLQFEARIAQRQSLVKQLHERQLDLLITTESPKMDELSSQLLGNFTLALYCASPAKNRNE
CEEHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCEEEEEEECCCCCCCCC
LNYLRLEWGPDFQQNEVGLIGSDDVPLLTTSSAELIYQQLSRLNGCCWLPARWAKEKHGL
CEEEEEEECCCCCCCCCCEECCCCCCEEECCHHHHHHHHHHHCCCEEECCHHHHHHHCCH
HTVMDSATLSRPLYAIWLQNSDKQAQIHEILKNPILE
HHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA