Click here to switch to the map view.

The map label for this gene is murI [H]

Identifier: 238892365

GI number: 238892365

Start: 119174

End: 120025

Strand: Direct

Name: murI [H]

Synonym: KP1_0122

Alternate gene names: 238892365

Gene position: 119174-120025 (Clockwise)

Preceding gene: 238892364

Following gene: 238892367

Centisome position: 2.27

GC content: 58.92

Gene sequence:

>852_bases
ATGGCTACCAATCTGCAGGACGGGAATACACCTTGTCTGGCAGCTACACCTTCTGATCCACGTCCCACCGTGCTGGTGTT
TGATTCCGGCGTCGGTGGGTTGTCGGTTTATAATGAGATTCGGCAGCTGCTGCCGAATCTGCATTACATCTATGCTTTCG
ATAACGTTGCCTTCCCCTATGGCGAGAAGAGCGAGGAGTTTATCGTTGAGCGCGTTGTGGAAATCGTCACTGCTGTCCAG
CAGCGTTATCCCCTGGCGCTGGCGGTGATCGCCTGCAATACCGCCAGTACCGTCTCCCTGCCTGCCCTGCGTGAAAAGTT
CGCTTTCCCCGTCGTTGGCGTGGTGCCGGCGATCAAGCCCGCCGCCCGTTTAACGGCGAACGGCATTGTTGGCCTGCTGG
CGACGCGCGGTACCGTAAAGCGTCCTTATACCCGTGAGCTGATCGACCGCTTTGCCAATGAATGTCGGATTGAAATGCTG
GGGTCGGCGGAGCTGGTGGAGCTGGCGGAAGCGAAGCTGCACGGCGAGCCTGTGCCGTTAGAAGAGCTGCGCCGTATCCT
GCGCCCATGGCTGCGGATGCAGGAGCCGCCGGATACGGTGGTGCTGGGCTGCACCCACTTTCCTCTTTTACAGGAGGAGC
TGCAGCGCGTTCTGCCGGAAGGCACACGGCTGATCGATTCCGGCGCGGCGATTGCCCGTCGCACCGCCTGGCTGTTAGAG
CATGAAGCGCCGGATGCGAAGTCCAGCGACGAGAATAAAGCATTCTGCATGGCGCTGACGGCAGAAACAGAACAGCTTTT
ACCCGTTCTGCGTCGCTATGGCTTCTCGACGCTGGAAAAATTACCGCTCTAA

Upstream 100 bases:

>100_bases
TTGAGCCTCTGGGATGTCGGTTTATCGTATCCCGTCACCTCACACCTGACAGTTCGTGGTAAAATAGCCAACCTGTTCGA
TAAAGATTACGAGACAGTTT

Downstream 100 bases:

>100_bases
GGGCGTTTTGCACAAAAAAGAGACGGTTGAATAATTTTTTGAAAACAGGGCTTGTCAACGTCTCAGAACTCCCTATAATG
CGCCTCCACTGACACGGAAC

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MATNLQDGNTPCLAATPSDPRPTVLVFDSGVGGLSVYNEIRQLLPNLHYIYAFDNVAFPYGEKSEEFIVERVVEIVTAVQ
QRYPLALAVIACNTASTVSLPALREKFAFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRPYTRELIDRFANECRIEML
GSAELVELAEAKLHGEPVPLEELRRILRPWLRMQEPPDTVVLGCTHFPLLQEELQRVLPEGTRLIDSGAAIARRTAWLLE
HEAPDAKSSDENKAFCMALTAETEQLLPVLRRYGFSTLEKLPL

Sequences:

>Translated_283_residues
MATNLQDGNTPCLAATPSDPRPTVLVFDSGVGGLSVYNEIRQLLPNLHYIYAFDNVAFPYGEKSEEFIVERVVEIVTAVQ
QRYPLALAVIACNTASTVSLPALREKFAFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRPYTRELIDRFANECRIEML
GSAELVELAEAKLHGEPVPLEELRRILRPWLRMQEPPDTVVLGCTHFPLLQEELQRVLPEGTRLIDSGAAIARRTAWLLE
HEAPDAKSSDENKAFCMALTAETEQLLPVLRRYGFSTLEKLPL
>Mature_282_residues
ATNLQDGNTPCLAATPSDPRPTVLVFDSGVGGLSVYNEIRQLLPNLHYIYAFDNVAFPYGEKSEEFIVERVVEIVTAVQQ
RYPLALAVIACNTASTVSLPALREKFAFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRPYTRELIDRFANECRIEMLG
SAELVELAEAKLHGEPVPLEELRRILRPWLRMQEPPDTVVLGCTHFPLLQEELQRVLPEGTRLIDSGAAIARRTAWLLEH
EAPDAKSSDENKAFCMALTAETEQLLPVLRRYGFSTLEKLPL

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis [H]

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family [H]

Homologues:

Organism=Escherichia coli, GI87082355, Length=281, Percent_Identity=88.2562277580071, Blast_Score=491, Evalue=1e-140,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391 [H]

Pfam domain/function: PF01177 Asp_Glu_race [H]

EC number: =5.1.1.3 [H]

Molecular weight: Translated: 31284; Mature: 31152

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00923 ASP_GLU_RACEMASE_1 ; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATNLQDGNTPCLAATPSDPRPTVLVFDSGVGGLSVYNEIRQLLPNLHYIYAFDNVAFPY
CCCCCCCCCCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCEECCC
GEKSEEFIVERVVEIVTAVQQRYPLALAVIACNTASTVSLPALREKFAFPVVGVVPAIKP
CCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHCCCH
AARLTANGIVGLLATRGTVKRPYTRELIDRFANECRIEMLGSAELVELAEAKLHGEPVPL
HHHHHHCCHHEEEECCCCCCCCHHHHHHHHHHHHHEEHCCCCHHHHHHHHHHHCCCCCCH
EELRRILRPWLRMQEPPDTVVLGCTHFPLLQEELQRVLPEGTRLIDSGAAIARRTAWLLE
HHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHCCCCCEEHHCCHHHHHHHHHHHH
HEAPDAKSSDENKAFCMALTAETEQLLPVLRRYGFSTLEKLPL
CCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCHHHHHHCCC
>Mature Secondary Structure 
ATNLQDGNTPCLAATPSDPRPTVLVFDSGVGGLSVYNEIRQLLPNLHYIYAFDNVAFPY
CCCCCCCCCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCEECCC
GEKSEEFIVERVVEIVTAVQQRYPLALAVIACNTASTVSLPALREKFAFPVVGVVPAIKP
CCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHCCCH
AARLTANGIVGLLATRGTVKRPYTRELIDRFANECRIEMLGSAELVELAEAKLHGEPVPL
HHHHHHCCHHEEEECCCCCCCCHHHHHHHHHHHHHEEHCCCCHHHHHHHHHHHCCCCCCH
EELRRILRPWLRMQEPPDTVVLGCTHFPLLQEELQRVLPEGTRLIDSGAAIARRTAWLLE
HHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHCCCCCEEHHCCHHHHHHHHHHHH
HEAPDAKSSDENKAFCMALTAETEQLLPVLRRYGFSTLEKLPL
CCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA