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The map label for this gene is rhaR

Identifier: 238892323

GI number: 238892323

Start: 73162

End: 74007

Strand: Direct

Name: rhaR

Synonym: KP1_0074

Alternate gene names: 238892323

Gene position: 73162-74007 (Clockwise)

Preceding gene: 238892322

Following gene: 238892325

Centisome position: 1.39

GC content: 61.23

Gene sequence:

>846_bases
GTGGCCGGTCTGATTTTACGTAAAGAGGAGTTTTTCCCTTCCGCCACACAGGCAGTGGCGGTGGCAGACCGCTACCCGCA
AAATGTCTTTGCCGAACATACCCATGAGTTCTGCGAGCTGGTGCTGGTGTGGCGAGGCAACGGGCTGCACGTCCTTAACG
ATCGTCCCTGGCGCATTACCCGCGGCGATCTGTTCTACATTCGCGCCGAAGATAAACACTCCTATGCTTCCGTTAACGAT
CTGGTTCTGCAGAACATCATCTATTGCCCGGAGCGGCTGCAGCTCAATTTTGACTGGGCCGGGGCGATCCCTGGCCTCTT
CGGCACGCCGTGGAAGCCCCACTGGCGCATGGGCAGCACAGGTATGGCGCAGGCGCGCCAGGTGATTAGCCAGCTTGAGC
ATGAGTGCGCCCGGCGCGACGCGCAGGGAAATGCGATGGCCGAACTGCTTTTTGCCCAGCTGGCGCTGACGTTGCAGCGC
CATCGCTACGCGACGGATGATCCCGCGGCGACGCAGCGCGAAGCGCTGCTGGACAAACTGCTGGCCGCGCTGGCGGCCAG
CCTTAGCCGCCCCTTTGTTCTGGAGCGTTTCTGCGAGCAGGAGGGCGGCAGCGAGCGGGCGCTTCGCCAGCAGTTTCGCC
AGCAAACCGGGATGACCATCAATCACTATTTACGCCAGCTGCGGATCTGCCATGCGCAGTATCTGCTGCAGCATACCGAG
CGCTTAATCGGCGATATCGCCATGCAGTGCGGCTTTGAGGACAGTAACTACTTTTCGGTGGTTTTTAGCCGGGAAATCGG
CATGTCACCGGGGCAATGGCGGCAGCGCAGTCGCGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
CAGGGGCGCGACGCCATTCTTCAGTAACGCGAGAAGAGTCAACGTATTGCAGACTAAAAACGCGAATAATGCGCCGTTAT
CCGCGTTTGGAGTGTGAGCC

Downstream 100 bases:

>100_bases
AGAGCGTCGTTGTCAGGCAGATGATCCGGTGATTAACTGGCCATTCCCAGACCGACGATATTGGCGGCGATGATAATCAC
CACGCAGCCGAGGCTCAGTA

Product: positive regulator for rhaRS operon

Products: NA

Alternate protein names: L-rhamnose operon transcriptional activator rhaR

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MAGLILRKEEFFPSATQAVAVADRYPQNVFAEHTHEFCELVLVWRGNGLHVLNDRPWRITRGDLFYIRAEDKHSYASVND
LVLQNIIYCPERLQLNFDWAGAIPGLFGTPWKPHWRMGSTGMAQARQVISQLEHECARRDAQGNAMAELLFAQLALTLQR
HRYATDDPAATQREALLDKLLAALAASLSRPFVLERFCEQEGGSERALRQQFRQQTGMTINHYLRQLRICHAQYLLQHTE
RLIGDIAMQCGFEDSNYFSVVFSREIGMSPGQWRQRSRAAA

Sequences:

>Translated_281_residues
MAGLILRKEEFFPSATQAVAVADRYPQNVFAEHTHEFCELVLVWRGNGLHVLNDRPWRITRGDLFYIRAEDKHSYASVND
LVLQNIIYCPERLQLNFDWAGAIPGLFGTPWKPHWRMGSTGMAQARQVISQLEHECARRDAQGNAMAELLFAQLALTLQR
HRYATDDPAATQREALLDKLLAALAASLSRPFVLERFCEQEGGSERALRQQFRQQTGMTINHYLRQLRICHAQYLLQHTE
RLIGDIAMQCGFEDSNYFSVVFSREIGMSPGQWRQRSRAAA
>Mature_280_residues
AGLILRKEEFFPSATQAVAVADRYPQNVFAEHTHEFCELVLVWRGNGLHVLNDRPWRITRGDLFYIRAEDKHSYASVNDL
VLQNIIYCPERLQLNFDWAGAIPGLFGTPWKPHWRMGSTGMAQARQVISQLEHECARRDAQGNAMAELLFAQLALTLQRH
RYATDDPAATQREALLDKLLAALAASLSRPFVLERFCEQEGGSERALRQQFRQQTGMTINHYLRQLRICHAQYLLQHTER
LIGDIAMQCGFEDSNYFSVVFSREIGMSPGQWRQRSRAAA

Specific function: Activates expression of the rhaSR operon in response to L-rhamnose

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HTH araC/xylS-type DNA-binding domains

Homologues:

Organism=Escherichia coli, GI171474011, Length=271, Percent_Identity=71.5867158671587, Blast_Score=420, Evalue=1e-119,
Organism=Escherichia coli, GI1790339, Length=272, Percent_Identity=36.3970588235294, Blast_Score=177, Evalue=7e-46,
Organism=Escherichia coli, GI1788725, Length=244, Percent_Identity=22.9508196721311, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RHAR_KLEP7 (A6TGB0)

Other databases:

- EMBL:   CP000647
- RefSeq:   YP_001337861.1
- ProteinModelPortal:   A6TGB0
- SMR:   A6TGB0
- STRING:   A6TGB0
- GeneID:   5339220
- GenomeReviews:   CP000647_GR
- KEGG:   kpn:KPN_04215
- eggNOG:   COG2207
- HOGENOM:   HBG467453
- OMA:   LRQLRIC
- ProtClustDB:   CLSK970681
- GO:   GO:0005737
- HAMAP:   MF_01533
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- Gene3D:   G3DSA:1.10.10.60
- PRINTS:   PR00032
- SMART:   SM00342

Pfam domain/function: PF02311 AraC_binding; PF00165 HTH_AraC; SSF51215 AraC_binding; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 32206; Mature: 32075

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS00041 HTH_ARAC_FAMILY_1; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLILRKEEFFPSATQAVAVADRYPQNVFAEHTHEFCELVLVWRGNGLHVLNDRPWRIT
CCCCEECHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCCEEEECCCCCEEE
RGDLFYIRAEDKHSYASVNDLVLQNIIYCPERLQLNFDWAGAIPGLFGTPWKPHWRMGST
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHEEEECCHHCCCCCCCCCCCCCCCCCCCC
GMAQARQVISQLEHECARRDAQGNAMAELLFAQLALTLQRHRYATDDPAATQREALLDKL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LAALAASLSRPFVLERFCEQEGGSERALRQQFRQQTGMTINHYLRQLRICHAQYLLQHTE
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RLIGDIAMQCGFEDSNYFSVVFSREIGMSPGQWRQRSRAAA
HHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCC
>Mature Secondary Structure 
AGLILRKEEFFPSATQAVAVADRYPQNVFAEHTHEFCELVLVWRGNGLHVLNDRPWRIT
CCCEECHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCCEEEECCCCCEEE
RGDLFYIRAEDKHSYASVNDLVLQNIIYCPERLQLNFDWAGAIPGLFGTPWKPHWRMGST
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHEEEECCHHCCCCCCCCCCCCCCCCCCCC
GMAQARQVISQLEHECARRDAQGNAMAELLFAQLALTLQRHRYATDDPAATQREALLDKL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LAALAASLSRPFVLERFCEQEGGSERALRQQFRQQTGMTINHYLRQLRICHAQYLLQHTE
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RLIGDIAMQCGFEDSNYFSVVFSREIGMSPGQWRQRSRAAA
HHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA