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The map label for this gene is trkD [H]

Identifier: 238892262

GI number: 238892262

Start: 5588

End: 7456

Strand: Direct

Name: trkD [H]

Synonym: KP1_0006

Alternate gene names: 238892262

Gene position: 5588-7456 (Clockwise)

Preceding gene: 238892259

Following gene: 238892263

Centisome position: 0.11

GC content: 56.98

Gene sequence:

>1869_bases
ATGAGCACTGATAATAAACAATCGTTGCCGGCGTTAACGCTGGCGGCCATCGGCGTGGTGTACGGCGATATCGGTACCAG
TCCACTGTATACCCTGCGCGAATGCCTGTCAGGTCAGTTTGGCTTTGGCGTAGAGCGCGATGCCGTTTTTGGCTTTTTGT
CGCTGATTTTCTGGCTGTTAATCTTTACCGTATCGATTAAATACATCACCTTCGTGATGCGGGCGGATAACGCCGGGGAA
GGCGGGATCTTAACGCTGATGTCGCTGGCCGGACGTAATACTTCGGCCAGAATGACCTCCGTGCTGGTGATCCTCGGCCT
TATCGGCGGCAGTTTCTTTTATGGCGAAGTGGTGATTACCCCGGCGATTTCGGTAATGTCGGCGATAGAGGGGTTAGAAA
TTATCGCCCCGCAGCTCGATACCTGGATTGTCCCTATCTCCATTATCGTGCTCACCCTGCTGTTTGTGATCCAGAAGCAC
GGGACTGGCATGGTCGGCAAGCTGTTTGCGCCGATTATGCTGATCTGGTTCCTGTTGCTGGCGGTGCTGGGCGCGCGAAG
CATTTACGCTAATCCGGAAGTTCTGCAGGCGCTGAACCCCTACTGGGCTGTGCACTTCTTCCTGCAATACAAGACCGTTT
CCTTTATTGCGCTTGGCGCGGTGGTGCTGTCGATTACCGGGGTGGAAGCGCTGTACGCCGATATGGGCCACTTCGGCAAA
CTGCCGATCCGCGTCGCCTGGTTCTCCGTCGTGCTGCCCTCGTTGGTGCTGAACTATTTTGGCCAGGGCGCGCTGCTGCT
GAAGCACCCGGAAGCGATTAAAAACCCGTTCTTCCTGCTGGCGCCTGAGTGGGCGCTGATCCCGATGCTGATTATCGCCA
CGCTGGCGACGGTTATCGCCTCCCAGGCAGTGATTTCCGGGGTCTTCTCCCTGACCCGTCAGGCAGTGCGTCTGGGCTAT
CTGTCGCCGATGCGCATTATCCATACCTCGGAAATGGAGTCCGGGCAGATTTACATTCCGTTCATTAACTGGCTGCTGTA
CGTTTCTGTGGTCATCGTTATCGTCAGCTTTGAGCATTCGTCTAACCTGGCGGCGGCGTATGGTATCGCCGTAACGGGCA
CCATGGTGCTGACCTCCATTCTGTCGGCGACCGTGGCGCGCAAAAACTGGCACTGGAACAAGCTGTTTGTCGGTCTGATG
CTGGTGGCCTTCCTGTGCATTGATATTCCGCTGTTCTCGGCGAACCTCGATAAGATTGTCTCCGGCGGCTGGCTACCGTT
GTCCCTGGGGATGGTGATGTTTACGGTGATGACGACCTGGAAGAGCGAGCGTTTCCGCCTGCTGCGCCGGATGCACGAGC
ATGGCAACTCGCTGGAAGCGATGATCTCTTCGCTGGAGAAGTCACCGCCAGTGCGTGTGCCGGGTACTGCGGTGTATATG
TCCCGCGCCCTGAACGTGATCCCGTTTGCCCTGCTGCATAACCTGAAGCACAACAAGGTGCTGCATGAGCGAGTGATCCT
CCTGACCCTGCGTACCGAAGATGCGCCTTACGTGCATAACGTTCGCCGGGTGCAGATTGAGCAGCTGTCACCGTCCTTCT
GGCGGGTGGTGGCCAGCTACGGCTGGCGGGAAACGCCTAACGTTGAAGAGGTGTTCCACCGCTGTGGCCTGGAAGGACTC
AGCTGCCGGATGATGGAGACCTCGTTCTTTATGTCGCATGAGTCGCTGATTATCGGCAAACGGCCATGGTATCTTCGCCT
GCGCGGCAAGCTTTATCTGCTGCTGCAGCGTAACGCCCTGCGGGCGCCGGATCAGTTTGAGATCCCGCCAAACCGGGTTA
TAGAGCTCGGTACCCAGGTCGAAATCTGA

Upstream 100 bases:

>100_bases
TGTTAGGGGTACGATTTCACAAATAATCGTGCATACTGTGCGCTTTTTGTGGGCCAAGGGACTAGGCACACATTTGTTTT
ATAAACGAAAAGACTAGTCT

Downstream 100 bases:

>100_bases
TGTCAAAAAAGCCCTTCCATTGCGAAGGGCTTTTTGTTTCTCACTCCGGTTGTTATGTCCTGTTGCTGTCTCGCGAAACG
TTTCGATGGCGATCACATTT

Product: potassium transport protein Kup

Products: K (I) [Cytoplasm] [C]

Alternate protein names: Kup system potassium uptake protein [H]

Number of amino acids: Translated: 622; Mature: 621

Protein sequence:

>622_residues
MSTDNKQSLPALTLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFTVSIKYITFVMRADNAGE
GGILTLMSLAGRNTSARMTSVLVILGLIGGSFFYGEVVITPAISVMSAIEGLEIIAPQLDTWIVPISIIVLTLLFVIQKH
GTGMVGKLFAPIMLIWFLLLAVLGARSIYANPEVLQALNPYWAVHFFLQYKTVSFIALGAVVLSITGVEALYADMGHFGK
LPIRVAWFSVVLPSLVLNYFGQGALLLKHPEAIKNPFFLLAPEWALIPMLIIATLATVIASQAVISGVFSLTRQAVRLGY
LSPMRIIHTSEMESGQIYIPFINWLLYVSVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSATVARKNWHWNKLFVGLM
LVAFLCIDIPLFSANLDKIVSGGWLPLSLGMVMFTVMTTWKSERFRLLRRMHEHGNSLEAMISSLEKSPPVRVPGTAVYM
SRALNVIPFALLHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPSFWRVVASYGWRETPNVEEVFHRCGLEGL
SCRMMETSFFMSHESLIIGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI

Sequences:

>Translated_622_residues
MSTDNKQSLPALTLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFTVSIKYITFVMRADNAGE
GGILTLMSLAGRNTSARMTSVLVILGLIGGSFFYGEVVITPAISVMSAIEGLEIIAPQLDTWIVPISIIVLTLLFVIQKH
GTGMVGKLFAPIMLIWFLLLAVLGARSIYANPEVLQALNPYWAVHFFLQYKTVSFIALGAVVLSITGVEALYADMGHFGK
LPIRVAWFSVVLPSLVLNYFGQGALLLKHPEAIKNPFFLLAPEWALIPMLIIATLATVIASQAVISGVFSLTRQAVRLGY
LSPMRIIHTSEMESGQIYIPFINWLLYVSVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSATVARKNWHWNKLFVGLM
LVAFLCIDIPLFSANLDKIVSGGWLPLSLGMVMFTVMTTWKSERFRLLRRMHEHGNSLEAMISSLEKSPPVRVPGTAVYM
SRALNVIPFALLHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPSFWRVVASYGWRETPNVEEVFHRCGLEGL
SCRMMETSFFMSHESLIIGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI
>Mature_621_residues
STDNKQSLPALTLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFTVSIKYITFVMRADNAGEG
GILTLMSLAGRNTSARMTSVLVILGLIGGSFFYGEVVITPAISVMSAIEGLEIIAPQLDTWIVPISIIVLTLLFVIQKHG
TGMVGKLFAPIMLIWFLLLAVLGARSIYANPEVLQALNPYWAVHFFLQYKTVSFIALGAVVLSITGVEALYADMGHFGKL
PIRVAWFSVVLPSLVLNYFGQGALLLKHPEAIKNPFFLLAPEWALIPMLIIATLATVIASQAVISGVFSLTRQAVRLGYL
SPMRIIHTSEMESGQIYIPFINWLLYVSVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSATVARKNWHWNKLFVGLML
VAFLCIDIPLFSANLDKIVSGGWLPLSLGMVMFTVMTTWKSERFRLLRRMHEHGNSLEAMISSLEKSPPVRVPGTAVYMS
RALNVIPFALLHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPSFWRVVASYGWRETPNVEEVFHRCGLEGLS
CRMMETSFFMSHESLIIGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI

Specific function: Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system) [H]

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family [H]

Homologues:

Organism=Escherichia coli, GI48994960, Length=622, Percent_Identity=92.604501607717, Blast_Score=1186, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003855
- InterPro:   IPR023051 [H]

Pfam domain/function: PF02705 K_trans [H]

EC number: NA

Molecular weight: Translated: 69260; Mature: 69129

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDNKQSLPALTLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLL
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
IFTVSIKYITFVMRADNAGEGGILTLMSLAGRNTSARMTSVLVILGLIGGSFFYGEVVIT
HHHHHHHHHHEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHCCHHHHH
PAISVMSAIEGLEIIAPQLDTWIVPISIIVLTLLFVIQKHGTGMVGKLFAPIMLIWFLLL
HHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AVLGARSIYANPEVLQALNPYWAVHFFLQYKTVSFIALGAVVLSITGVEALYADMGHFGK
HHHCCCHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LPIRVAWFSVVLPSLVLNYFGQGALLLKHPEAIKNPFFLLAPEWALIPMLIIATLATVIA
CCHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHCCCEEEECCCHHHHHHHHHHHHHHHHH
SQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFINWLLYVSVVIVIVSFEHS
HHHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCCEEEHHHHHHHHHHHHHHHHHCCCCC
SNLAAAYGIAVTGTMVLTSILSATVARKNWHWNKLFVGLMLVAFLCIDIPLFSANLDKIV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHCCCHHHHH
SGGWLPLSLGMVMFTVMTTWKSERFRLLRRMHEHGNSLEAMISSLEKSPPVRVPGTAVYM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHH
SRALNVIPFALLHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPSFWRVVASY
HHHHHHHHHHHHHHCHHHHHHHCEEEEEEEECCCCCHHHHHHHEEHHHCCHHHHHHHHHC
GWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLIIGKRPWYLRLRGKLYLLLQRNAL
CCCCCCCHHHHHHHCCCCCCEEEEEHHHHHHCCCCEEEECCCEEEEECCEEEEEEECCCC
RAPDQFEIPPNRVIELGTQVEI
CCCCCCCCCHHHHHCCCCCCCC
>Mature Secondary Structure 
STDNKQSLPALTLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLL
CCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
IFTVSIKYITFVMRADNAGEGGILTLMSLAGRNTSARMTSVLVILGLIGGSFFYGEVVIT
HHHHHHHHHHEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHCCHHHHH
PAISVMSAIEGLEIIAPQLDTWIVPISIIVLTLLFVIQKHGTGMVGKLFAPIMLIWFLLL
HHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AVLGARSIYANPEVLQALNPYWAVHFFLQYKTVSFIALGAVVLSITGVEALYADMGHFGK
HHHCCCHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LPIRVAWFSVVLPSLVLNYFGQGALLLKHPEAIKNPFFLLAPEWALIPMLIIATLATVIA
CCHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHCCCEEEECCCHHHHHHHHHHHHHHHHH
SQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFINWLLYVSVVIVIVSFEHS
HHHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCCEEEHHHHHHHHHHHHHHHHHCCCCC
SNLAAAYGIAVTGTMVLTSILSATVARKNWHWNKLFVGLMLVAFLCIDIPLFSANLDKIV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHCCCHHHHH
SGGWLPLSLGMVMFTVMTTWKSERFRLLRRMHEHGNSLEAMISSLEKSPPVRVPGTAVYM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHH
SRALNVIPFALLHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPSFWRVVASY
HHHHHHHHHHHHHHCHHHHHHHCEEEEEEEECCCCCHHHHHHHEEHHHCCHHHHHHHHHC
GWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLIIGKRPWYLRLRGKLYLLLQRNAL
CCCCCCCHHHHHHHCCCCCCEEEEEHHHHHHCCCCEEEECCCEEEEECCEEEEEEECCCC
RAPDQFEIPPNRVIELGTQVEI
CCCCCCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA