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The map label for this gene is aaeR [H]

Identifier: 238028822

GI number: 238028822

Start: 3739596

End: 3740519

Strand: Direct

Name: aaeR [H]

Synonym: bglu_1g32870

Alternate gene names: 238028822

Gene position: 3739596-3740519 (Clockwise)

Preceding gene: 238028821

Following gene: 238028823

Centisome position: 95.73

GC content: 73.16

Gene sequence:

>924_bases
ATGAACCAGCTCCAGGCCATGCGCGTCTTCACGCGCGTCGTCGATCTCGCAAGCTTCAACCTCGCGGCCCGGCAGCTCGG
CATGTCGGCCGCCGCCGTCACGCGCAGCGTGGGCATGCTCGAGGCGCACCTCAACATGCGCCTGCTGAACCGCACCACGC
GCAGCCTGTCGCTGACCGAGGCGGGCCGCGAGTATCTGGAGGGCTGCCGCGTGATCATCGAGAAGCTCGAAGAGATCGAG
TCGAACCTGGTGCGCGCCTCGCGCGAGCCGCGCGGCACGCTGCGCATCGCCGCGTCGATGTGCTTCGCCGCGGCGGGCCT
CGGCGAGCTGCTGGCCGCCTACCGCGCCCAGCATCCGCGCGTGGGCTTCGACGTGACCACCTTCGACACGCACGTCGACA
TGGTGGAGGGCGGCTACGACGTCTGCTTCGCGGACGATCGCCGGCTGGCCAGCGCCACGCTGGTGTCGCGGCCGCTCACC
ACGGTGCGCGAGGTGGTGGTGGCCTCGCCCGCCTATCTGGCGCGCCACGGGCGCCCGGCCGTGCCCGCCGCGCTCAACGA
GCACAGCCTGCTGACGGTCTCGGACGGCGCCGCGCGCAACTGGGAATTCACCGACGGCGACGCACTCTGCCGCATCGTCA
CCGGCCACGCGCTCGCCGCCAGCGGCAGCGCGATGGTGCGCCTGGCCGCGCTCGCCCACCTGGGCGTGGCGCTGCTGCCC
GAGCCGCTGGTGGCGGGCGACCTCGTGCGCGGCGAGCTGGTCGCGCTGCTCGAGGGCTACCCGGTCAACGGCGGGCCGCG
CGGCATCTCGATCCTCTACCCGGGGCGCCACTACCTCTCCATGAAGGTGCGCAGCTTCGTCGATTTCGCGGTGGGCCGCT
ATCGCGGCGCCGACCGCGCCGCGCCGCTGCGCGCCGTCGCCTGA

Upstream 100 bases:

>100_bases
CGGCCGTGCCCGCCGCCGAGCCAAGCGGCACCTCGACGGCGCCGCGGCGTGATTCGCGACGGCCGCTCCTGAACGCCTCG
CCATCGTTGCCCATACTTCC

Downstream 100 bases:

>100_bases
CCCGCGGCCCATGTCGAAGATCCTGACGATCGAGGACGATGTCCTGATCGCCGACAGCATCACGCGCCAGCTGCAGGCCG
AGGGCCATACGGTGGACCTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNQLQAMRVFTRVVDLASFNLAARQLGMSAAAVTRSVGMLEAHLNMRLLNRTTRSLSLTEAGREYLEGCRVIIEKLEEIE
SNLVRASREPRGTLRIAASMCFAAAGLGELLAAYRAQHPRVGFDVTTFDTHVDMVEGGYDVCFADDRRLASATLVSRPLT
TVREVVVASPAYLARHGRPAVPAALNEHSLLTVSDGAARNWEFTDGDALCRIVTGHALAASGSAMVRLAALAHLGVALLP
EPLVAGDLVRGELVALLEGYPVNGGPRGISILYPGRHYLSMKVRSFVDFAVGRYRGADRAAPLRAVA

Sequences:

>Translated_307_residues
MNQLQAMRVFTRVVDLASFNLAARQLGMSAAAVTRSVGMLEAHLNMRLLNRTTRSLSLTEAGREYLEGCRVIIEKLEEIE
SNLVRASREPRGTLRIAASMCFAAAGLGELLAAYRAQHPRVGFDVTTFDTHVDMVEGGYDVCFADDRRLASATLVSRPLT
TVREVVVASPAYLARHGRPAVPAALNEHSLLTVSDGAARNWEFTDGDALCRIVTGHALAASGSAMVRLAALAHLGVALLP
EPLVAGDLVRGELVALLEGYPVNGGPRGISILYPGRHYLSMKVRSFVDFAVGRYRGADRAAPLRAVA
>Mature_307_residues
MNQLQAMRVFTRVVDLASFNLAARQLGMSAAAVTRSVGMLEAHLNMRLLNRTTRSLSLTEAGREYLEGCRVIIEKLEEIE
SNLVRASREPRGTLRIAASMCFAAAGLGELLAAYRAQHPRVGFDVTTFDTHVDMVEGGYDVCFADDRRLASATLVSRPLT
TVREVVVASPAYLARHGRPAVPAALNEHSLLTVSDGAARNWEFTDGDALCRIVTGHALAASGSAMVRLAALAHLGVALLP
EPLVAGDLVRGELVALLEGYPVNGGPRGISILYPGRHYLSMKVRSFVDFAVGRYRGADRAAPLRAVA

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=290, Percent_Identity=34.1379310344828, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=31.25, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=28.8135593220339, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787128, Length=279, Percent_Identity=31.1827956989247, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI87081978, Length=290, Percent_Identity=28.9655172413793, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789440, Length=286, Percent_Identity=26.5734265734266, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788706, Length=292, Percent_Identity=26.7123287671233, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789173, Length=252, Percent_Identity=29.3650793650794, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787589, Length=299, Percent_Identity=24.0802675585284, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788748, Length=120, Percent_Identity=31.6666666666667, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI145693105, Length=117, Percent_Identity=30.7692307692308, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33021; Mature: 33021

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLQAMRVFTRVVDLASFNLAARQLGMSAAAVTRSVGMLEAHLNMRLLNRTTRSLSLTE
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGREYLEGCRVIIEKLEEIESNLVRASREPRGTLRIAASMCFAAAGLGELLAAYRAQHPR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCC
VGFDVTTFDTHVDMVEGGYDVCFADDRRLASATLVSRPLTTVREVVVASPAYLARHGRPA
CCCEEEEECCHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
VPAALNEHSLLTVSDGAARNWEFTDGDALCRIVTGHALAASGSAMVRLAALAHLGVALLP
CCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHCC
EPLVAGDLVRGELVALLEGYPVNGGPRGISILYPGRHYLSMKVRSFVDFAVGRYRGADRA
CCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
APLRAVA
CCCCCCC
>Mature Secondary Structure
MNQLQAMRVFTRVVDLASFNLAARQLGMSAAAVTRSVGMLEAHLNMRLLNRTTRSLSLTE
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGREYLEGCRVIIEKLEEIESNLVRASREPRGTLRIAASMCFAAAGLGELLAAYRAQHPR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCC
VGFDVTTFDTHVDMVEGGYDVCFADDRRLASATLVSRPLTTVREVVVASPAYLARHGRPA
CCCEEEEECCHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
VPAALNEHSLLTVSDGAARNWEFTDGDALCRIVTGHALAASGSAMVRLAALAHLGVALLP
CCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHCC
EPLVAGDLVRGELVALLEGYPVNGGPRGISILYPGRHYLSMKVRSFVDFAVGRYRGADRA
CCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
APLRAVA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]