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The map label for this gene is ttcA [H]

Identifier: 238028813

GI number: 238028813

Start: 3728396

End: 3729385

Strand: Direct

Name: ttcA [H]

Synonym: bglu_1g32770

Alternate gene names: 238028813

Gene position: 3728396-3729385 (Clockwise)

Preceding gene: 238028812

Following gene: 238028814

Centisome position: 95.44

GC content: 68.08

Gene sequence:

>990_bases
ATGAACGCCCCCCATACCCCCGCACACGCCGAGGCCGCGCAGGCCGTCGAGGCCAACGTCGCCGATCTCGGCCGCCGCGC
GCTCACGCGCCGCGAGCAGAAGGAGGCCTACGAGAACAACAAGCTGTTCAAGCGGCTCGCGCGCCAGGTCGGCCAGGCGA
TCGGCGACTACAACATGATCGAGGACGGCGACAAGGTGATGGTCTGCCTGTCGGGCGGCAAGGACAGCTACGCGATGCTC
GACATCCTGCTGCGCCTGCGCGAGCGCGCGCCGATCGACTTCGAGATCGTCGCCGTCAACCTCGACCAGAAGCAGCCGGG
CTTTCCCGAGCACGTCCTGCCCGAGTACCTGACGCGGATCGGCGTGCCGTTCCACATCGAGAACCAGGACACCTACAGCA
TCGTCAAGCGGCTGGTGCCCGAGGGCAAGACCACCTGCTCGCTGTGCTCGCGGCTGCGCCGCGGCATCCTCTACCGCGTG
GCGGGCGAGCTCGGCGCCACCAAGATCGCGCTCGGCCACCATCGCGACGACATCCTGCAGACGCTGCTGCTGAACCTGTT
CTACGGCGGCAAGCTCAAGGGCATGCCGCCCAAGCTGCAGTCCGACGACGGCAGGAACATCGTGATCCGCCCGCTCGCCT
ACGTGAAGGAAGTCGATCTCGAGAAGTACGCCGAGCTGCGCGAATTCCCGATCATCCCGTGCAACCTCTGCGGCAGCCAG
CCGAACCTGAAGCGCGCCGAGATGAAGGCGCTGGTGCGCGACTGGGACAAGCGCTTCCCGGGCCGCGTCGACAACATGTT
CAGCGCGCTCGCCAACGTCGTGCCCTCGCACCTGATGGACACCGGGCTGTTCCCGTTCGCCGGGCTGCGCGCCACCGGCC
AGGCCGACCCGGCCGGCGACATCGCGTTCGACGAGGAGCCGTGCGGCACCGGCGCGCCGGACGCGGGCGGCGCCAGGCCG
ATCTCGATCGTATCGTTCGACGATCTGTAA

Upstream 100 bases:

>100_bases
CCGTGCGCGCGGTGCGCGTCTCCACCGAGAAACCGGACGCCTACCCCGATTGCGACGCAGTGGGCGTCGAAGTCTTCCGC
ATCAAGGACGAGGAGCGCGC

Downstream 100 bases:

>100_bases
CAATCCCGCTCGATTGCCGCGAAACGCCCGCCGGATGGGCGTTTCGCGGCACGGCGCGGCGCCGCCCGGCGCGATCGGCG
CGCCCCCTGCGTGCTAGAAT

Product: tRNA 2-thiocytidine biosynthesis protein TtcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNAPHTPAHAEAAQAVEANVADLGRRALTRREQKEAYENNKLFKRLARQVGQAIGDYNMIEDGDKVMVCLSGGKDSYAML
DILLRLRERAPIDFEIVAVNLDQKQPGFPEHVLPEYLTRIGVPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGILYRV
AGELGATKIALGHHRDDILQTLLLNLFYGGKLKGMPPKLQSDDGRNIVIRPLAYVKEVDLEKYAELREFPIIPCNLCGSQ
PNLKRAEMKALVRDWDKRFPGRVDNMFSALANVVPSHLMDTGLFPFAGLRATGQADPAGDIAFDEEPCGTGAPDAGGARP
ISIVSFDDL

Sequences:

>Translated_329_residues
MNAPHTPAHAEAAQAVEANVADLGRRALTRREQKEAYENNKLFKRLARQVGQAIGDYNMIEDGDKVMVCLSGGKDSYAML
DILLRLRERAPIDFEIVAVNLDQKQPGFPEHVLPEYLTRIGVPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGILYRV
AGELGATKIALGHHRDDILQTLLLNLFYGGKLKGMPPKLQSDDGRNIVIRPLAYVKEVDLEKYAELREFPIIPCNLCGSQ
PNLKRAEMKALVRDWDKRFPGRVDNMFSALANVVPSHLMDTGLFPFAGLRATGQADPAGDIAFDEEPCGTGAPDAGGARP
ISIVSFDDL
>Mature_329_residues
MNAPHTPAHAEAAQAVEANVADLGRRALTRREQKEAYENNKLFKRLARQVGQAIGDYNMIEDGDKVMVCLSGGKDSYAML
DILLRLRERAPIDFEIVAVNLDQKQPGFPEHVLPEYLTRIGVPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGILYRV
AGELGATKIALGHHRDDILQTLLLNLFYGGKLKGMPPKLQSDDGRNIVIRPLAYVKEVDLEKYAELREFPIIPCNLCGSQ
PNLKRAEMKALVRDWDKRFPGRVDNMFSALANVVPSHLMDTGLFPFAGLRATGQADPAGDIAFDEEPCGTGAPDAGGARP
ISIVSFDDL

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=274, Percent_Identity=68.6131386861314, Blast_Score=410, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI193211090, Length=273, Percent_Identity=31.5018315018315, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17540090, Length=237, Percent_Identity=28.6919831223629, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24651972, Length=246, Percent_Identity=27.6422764227642, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 36406; Mature: 36406

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPHTPAHAEAAQAVEANVADLGRRALTRREQKEAYENNKLFKRLARQVGQAIGDYNMI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EDGDKVMVCLSGGKDSYAMLDILLRLRERAPIDFEIVAVNLDQKQPGFPEHVLPEYLTRI
CCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHC
GVPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGILYRVAGELGATKIALGHHRDDILQ
CCCEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHH
TLLLNLFYGGKLKGMPPKLQSDDGRNIVIRPLAYVKEVDLEKYAELREFPIIPCNLCGSQ
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCHHHHHHHHHCCCCCHHCCCCC
PNLKRAEMKALVRDWDKRFPGRVDNMFSALANVVPSHLMDTGLFPFAGLRATGQADPAGD
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
IAFDEEPCGTGAPDAGGARPISIVSFDDL
CCCCCCCCCCCCCCCCCCCCEEEEECCCC
>Mature Secondary Structure
MNAPHTPAHAEAAQAVEANVADLGRRALTRREQKEAYENNKLFKRLARQVGQAIGDYNMI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EDGDKVMVCLSGGKDSYAMLDILLRLRERAPIDFEIVAVNLDQKQPGFPEHVLPEYLTRI
CCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHC
GVPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGILYRVAGELGATKIALGHHRDDILQ
CCCEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHH
TLLLNLFYGGKLKGMPPKLQSDDGRNIVIRPLAYVKEVDLEKYAELREFPIIPCNLCGSQ
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCHHHHHHHHHCCCCCHHCCCCC
PNLKRAEMKALVRDWDKRFPGRVDNMFSALANVVPSHLMDTGLFPFAGLRATGQADPAGD
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
IAFDEEPCGTGAPDAGGARPISIVSFDDL
CCCCCCCCCCCCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA