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The map label for this gene is hldE [H]

Identifier: 238028755

GI number: 238028755

Start: 3655187

End: 3655672

Strand: Reverse

Name: hldE [H]

Synonym: bglu_1g32190

Alternate gene names: 238028755

Gene position: 3655672-3655187 (Counterclockwise)

Preceding gene: 238028756

Following gene: 238028752

Centisome position: 93.58

GC content: 69.34

Gene sequence:

>486_bases
ATGCCCGCCGCCTTCGAACGTAAATTCATCCGCCGCGACGCGCTCGCCGCGCTGCGCCCGACCCTGCCGTCACCCGTGGT
GTTCACGAACGGTGTGTTCGACATCCTGCATCGCGGCCACGTCACCTACCTGGCCGACGCACGCGCGCTCGGCGCCTGCC
TGATCGTCGCCGTCAACAGCGACGCCTCGGTGCGCCTGCTCGGCAAGGGCGACGACCGGCCGATCAATCGCCAGGAGGAT
CGCATGGCGCTGCTCGCGGCGCTGGAATGCGTCGACTGGGTGGTCGGTTTCGAGGAGCAGACGCCGGTGGCGCTGATTGA
GGCGGTGCGCCCCGACATCCTGGTCAAGGGCGGTGACTACGACATGGACGCGCTGCCCGAAGCGGCGCTCGTGCGCGGCT
GGGGCGGCAAGGCGCTGGCGATTCCGTTCGAGTTCGAGCGCTCGACCACGGCGCTTCTGAAGAAGGTGCGCGCCCACCAG
GGCTGA

Upstream 100 bases:

>100_bases
GCGGTGGCCGAACCCGCCACCCCGTGGCCGCCGGGCAGCCCGGCGAGCCGCTCGGCGCCTGCCGCTTCCCGCGCCGACCT
TTCGACCGGAGTCCATGCCG

Downstream 100 bases:

>100_bases
GCCCCGGCGCGCCGGTTCAGGCGCGCGACGCCTTGTGGCGCGGCGCTGCGGTGCGCGGCTTGGGCTTGGCGCGCGCCTTG
GCGGCCGCGCGGCGCGACCG

Product: putative cytidylyltransferase

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MPAAFERKFIRRDALAALRPTLPSPVVFTNGVFDILHRGHVTYLADARALGACLIVAVNSDASVRLLGKGDDRPINRQED
RMALLAALECVDWVVGFEEQTPVALIEAVRPDILVKGGDYDMDALPEAALVRGWGGKALAIPFEFERSTTALLKKVRAHQ
G

Sequences:

>Translated_161_residues
MPAAFERKFIRRDALAALRPTLPSPVVFTNGVFDILHRGHVTYLADARALGACLIVAVNSDASVRLLGKGDDRPINRQED
RMALLAALECVDWVVGFEEQTPVALIEAVRPDILVKGGDYDMDALPEAALVRGWGGKALAIPFEFERSTTALLKKVRAHQ
G
>Mature_160_residues
PAAFERKFIRRDALAALRPTLPSPVVFTNGVFDILHRGHVTYLADARALGACLIVAVNSDASVRLLGKGDDRPINRQEDR
MALLAALECVDWVVGFEEQTPVALIEAVRPDILVKGGDYDMDALPEAALVRGWGGKALAIPFEFERSTTALLKKVRAHQG

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=132, Percent_Identity=58.3333333333333, Blast_Score=146, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 17562; Mature: 17430

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAAFERKFIRRDALAALRPTLPSPVVFTNGVFDILHRGHVTYLADARALGACLIVAVNS
CCCHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHCCCEEEEECHHHCCEEEEEEECC
DASVRLLGKGDDRPINRQEDRMALLAALECVDWVVGFEEQTPVALIEAVRPDILVKGGDY
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCCC
DMDALPEAALVRGWGGKALAIPFEFERSTTALLKKVRAHQG
CHHHCCCHHEEECCCCCEEEEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PAAFERKFIRRDALAALRPTLPSPVVFTNGVFDILHRGHVTYLADARALGACLIVAVNS
CCHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHCCCEEEEECHHHCCEEEEEEECC
DASVRLLGKGDDRPINRQEDRMALLAALECVDWVVGFEEQTPVALIEAVRPDILVKGGDY
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCCC
DMDALPEAALVRGWGGKALAIPFEFERSTTALLKKVRAHQG
CHHHCCCHHEEECCCCCEEEEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA