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The map label for this gene is dacC [H]

Identifier: 238028745

GI number: 238028745

Start: 3644391

End: 3645692

Strand: Reverse

Name: dacC [H]

Synonym: bglu_1g32090

Alternate gene names: 238028745

Gene position: 3645692-3644391 (Counterclockwise)

Preceding gene: 238028746

Following gene: 238028744

Centisome position: 93.32

GC content: 68.74

Gene sequence:

>1302_bases
ATGCGTTTGTCCTCCGTAGGCCTCAAGTCCCTCGCTTCTTCCACCGCCTTGGCCGCCGCCGCGCGCAACGTCGCGCTCGG
TGTGGTCATGCCCGCCGCGCTCGTGACCACGGTCGCCGTCGCGCAGGCCAAGCCCGCCGCCAGGGCCAAGGCCGCCGCGG
CCGCCGAGGCGCCGACCGGCGCGCCGGCCACCTACCTGCCGGGCGCGGTGCCGCCGCCCGGCGTCAACGCGCGCTCGTGG
GTGCTGGTCGACGCGAGCAGCAACCAGGTGCTCGCCTCCGGCAACGCGGACGAGCGCGTCGAGCCCGCTTCGCTGACCAA
GCTGATGACGGCCTACCTGGTGTTCGAGGCGCTCGCGTCGAAGAAGATCTCGATGGAGCAGATCGTGACGCCGAGCGAGG
CGGTGCGCCGCGTCGGCACCGACGAGTCGCGCATGTTCATCGAGGCGAACAAGCCGGTGTCGGTCCATGATCTCGTCTAC
GGGATGATCATCCAGTCGGGCAACGACGCCGCGATCGCGCTGGCCGAGCTGGTCGGCGGCAGCGAAGCGCAGTTCGTCAA
CATGATGAACGCCGAGGCGCAGAAGCTCGGCATGAAGGGCACCCACTTCGCCGACGTGAACGGCATGCCCGACCCGCAGC
ACTACACCACGGCGGGCGACCTCGCCGTGCTGTCGGCGCGCCTGATCCGCGACTTCCCCGACTACTACAACATCTTCTCG
GTGAAGGACTTCACCTACAACCACATCCGCCAGCCCAACCGCAACCGGCTGCTGTGGATCGACCCGACCGTGGACGGCCT
GAAGACCGGCCACACCCAGGCGGCCGGCTACTGCCTGATCGCCTCGGCCAAGCGCCCGCTGCCGGGCTCGGCCGACGTCT
CGCGCCGCCTGGTGACGGTGATGATGGGCGAGCCGAGGGAAAGCGACCGCGTGCAGGACAGCCTGAAGATGCTGAACTAC
GGCTACAGCGCGTTCGATACGGTGCGCCTCTACAAGGGCGGCCAGGCGGTGGAAACGCCGCGCGTCTACAAGGGCCGGGT
CAACTCGGTGCCGGTCGGCGTGCAGAAGGACCAGTTCGTGACGCTGCCCAAGGGCGCGGGCGACAAGCTCAAGCCGCAGG
TCACGCTGAACACGCCGCTCATCGCGCCGCTCGCCGAAGGCCAGCAGGTCGGCACGGTGCAGTTCGTGGCGGACGGCAAG
ACGGTCGCGCAGTTCCCGATCGTCGCGCTGCAGGCGGTGCCGGAAGCGGGCTTCTTCGGCCGTCTCTGGGATTCGATCCT
GCTGATGTTCAGCAAGAAGTAA

Upstream 100 bases:

>100_bases
CCCGGCTCCGCCCAGATGCCGCGGCCGGACCGCTCGCCGTCCCGGTTCCCCGATCTCGCGCCCCGTGCGCAGCACTTTCT
GCCATCTGCCTGAATCGATC

Downstream 100 bases:

>100_bases
GCAGACGCCGGTGCGGCATGGCCCGGCGCGCGCACCGCGCCGGGCCATGCCGAGCTGCCGCAACCCGCGCTGTGCCGTGG
TCGACTCGGACGCATCGCCA

Product: D-alanyl-D-alanine carboxypeptidase family protein

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MRLSSVGLKSLASSTALAAAARNVALGVVMPAALVTTVAVAQAKPAARAKAAAAAEAPTGAPATYLPGAVPPPGVNARSW
VLVDASSNQVLASGNADERVEPASLTKLMTAYLVFEALASKKISMEQIVTPSEAVRRVGTDESRMFIEANKPVSVHDLVY
GMIIQSGNDAAIALAELVGGSEAQFVNMMNAEAQKLGMKGTHFADVNGMPDPQHYTTAGDLAVLSARLIRDFPDYYNIFS
VKDFTYNHIRQPNRNRLLWIDPTVDGLKTGHTQAAGYCLIASAKRPLPGSADVSRRLVTVMMGEPRESDRVQDSLKMLNY
GYSAFDTVRLYKGGQAVETPRVYKGRVNSVPVGVQKDQFVTLPKGAGDKLKPQVTLNTPLIAPLAEGQQVGTVQFVADGK
TVAQFPIVALQAVPEAGFFGRLWDSILLMFSKK

Sequences:

>Translated_433_residues
MRLSSVGLKSLASSTALAAAARNVALGVVMPAALVTTVAVAQAKPAARAKAAAAAEAPTGAPATYLPGAVPPPGVNARSW
VLVDASSNQVLASGNADERVEPASLTKLMTAYLVFEALASKKISMEQIVTPSEAVRRVGTDESRMFIEANKPVSVHDLVY
GMIIQSGNDAAIALAELVGGSEAQFVNMMNAEAQKLGMKGTHFADVNGMPDPQHYTTAGDLAVLSARLIRDFPDYYNIFS
VKDFTYNHIRQPNRNRLLWIDPTVDGLKTGHTQAAGYCLIASAKRPLPGSADVSRRLVTVMMGEPRESDRVQDSLKMLNY
GYSAFDTVRLYKGGQAVETPRVYKGRVNSVPVGVQKDQFVTLPKGAGDKLKPQVTLNTPLIAPLAEGQQVGTVQFVADGK
TVAQFPIVALQAVPEAGFFGRLWDSILLMFSKK
>Mature_433_residues
MRLSSVGLKSLASSTALAAAARNVALGVVMPAALVTTVAVAQAKPAARAKAAAAAEAPTGAPATYLPGAVPPPGVNARSW
VLVDASSNQVLASGNADERVEPASLTKLMTAYLVFEALASKKISMEQIVTPSEAVRRVGTDESRMFIEANKPVSVHDLVY
GMIIQSGNDAAIALAELVGGSEAQFVNMMNAEAQKLGMKGTHFADVNGMPDPQHYTTAGDLAVLSARLIRDFPDYYNIFS
VKDFTYNHIRQPNRNRLLWIDPTVDGLKTGHTQAAGYCLIASAKRPLPGSADVSRRLVTVMMGEPRESDRVQDSLKMLNY
GYSAFDTVRLYKGGQAVETPRVYKGRVNSVPVGVQKDQFVTLPKGAGDKLKPQVTLNTPLIAPLAEGQQVGTVQFVADGK
TVAQFPIVALQAVPEAGFFGRLWDSILLMFSKK

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=400, Percent_Identity=42.25, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1786851, Length=411, Percent_Identity=38.9294403892944, Blast_Score=279, Evalue=3e-76,
Organism=Escherichia coli, GI87082022, Length=380, Percent_Identity=40.5263157894737, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI87082054, Length=217, Percent_Identity=29.4930875576037, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 46143; Mature: 46143

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSSVGLKSLASSTALAAAARNVALGVVMPAALVTTVAVAQAKPAARAKAAAAAEAPTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
APATYLPGAVPPPGVNARSWVLVDASSNQVLASGNADERVEPASLTKLMTAYLVFEALAS
CCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
KKISMEQIVTPSEAVRRVGTDESRMFIEANKPVSVHDLVYGMIIQSGNDAAIALAELVGG
CCCCHHHHCCHHHHHHHCCCCCCEEEEECCCCCCHHHHHEEHEEECCCCHHEEHHHHHCC
SEAQFVNMMNAEAQKLGMKGTHFADVNGMPDPQHYTTAGDLAVLSARLIRDFPDYYNIFS
CHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCEEE
VKDFTYNHIRQPNRNRLLWIDPTVDGLKTGHTQAAGYCLIASAKRPLPGSADVSRRLVTV
EECCCHHHHCCCCCCEEEEECCCCCCHHCCCCCCCCEEEEECCCCCCCCCCHHHHHEEEE
MMGEPRESDRVQDSLKMLNYGYSAFDTVRLYKGGQAVETPRVYKGRVNSVPVGVQKDQFV
EECCCCCHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCEE
TLPKGAGDKLKPQVTLNTPLIAPLAEGQQVGTVQFVADGKTVAQFPIVALQAVPEAGFFG
ECCCCCCCCCCCEEEECCCCEEECCCCCCCCEEEEEECCCCHHHHHHHHEECCCCCCHHH
RLWDSILLMFSKK
HHHHHHHHHHCCC
>Mature Secondary Structure
MRLSSVGLKSLASSTALAAAARNVALGVVMPAALVTTVAVAQAKPAARAKAAAAAEAPTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
APATYLPGAVPPPGVNARSWVLVDASSNQVLASGNADERVEPASLTKLMTAYLVFEALAS
CCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
KKISMEQIVTPSEAVRRVGTDESRMFIEANKPVSVHDLVYGMIIQSGNDAAIALAELVGG
CCCCHHHHCCHHHHHHHCCCCCCEEEEECCCCCCHHHHHEEHEEECCCCHHEEHHHHHCC
SEAQFVNMMNAEAQKLGMKGTHFADVNGMPDPQHYTTAGDLAVLSARLIRDFPDYYNIFS
CHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCEEE
VKDFTYNHIRQPNRNRLLWIDPTVDGLKTGHTQAAGYCLIASAKRPLPGSADVSRRLVTV
EECCCHHHHCCCCCCEEEEECCCCCCHHCCCCCCCCEEEEECCCCCCCCCCHHHHHEEEE
MMGEPRESDRVQDSLKMLNYGYSAFDTVRLYKGGQAVETPRVYKGRVNSVPVGVQKDQFV
EECCCCCHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCEE
TLPKGAGDKLKPQVTLNTPLIAPLAEGQQVGTVQFVADGKTVAQFPIVALQAVPEAGFFG
ECCCCCCCCCCCEEEECCCCEEECCCCCCCCEEEEEECCCCHHHHHHHHEECCCCCCHHH
RLWDSILLMFSKK
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]