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The map label for this gene is moeB [H]

Identifier: 238028717

GI number: 238028717

Start: 3612740

End: 3613492

Strand: Direct

Name: moeB [H]

Synonym: bglu_1g31810

Alternate gene names: 238028717

Gene position: 3612740-3613492 (Clockwise)

Preceding gene: 238028716

Following gene: 238028725

Centisome position: 92.48

GC content: 70.12

Gene sequence:

>753_bases
ATGAACGACGAACAACTGCTCCGCTATTCCCGCCACATCCTCGTCGACGAAATCGGCATCGAGGCGCAGCAGCGCTTCCT
CGACGCGCACGCGCTGATCGTCGGGGCCGGCGGCCTCGGATCGCCGGCCGCGATGTACCTGGCCGCCGCGGGCGTGGGCG
CGATCACGCTGGTCGATGCCGACACGGTGGACCTCACCAACCTGCAGCGCCAGATCCTGCATGCGACCGAATCGGTCGGG
CGGCGCAAGGTCGAGTCGGGGCGCGAGGCGCTCGCGCGGCTCAACCCCGAGATCGTCGTGCATGCGGTGGCCGAGCGCGT
CGGGGCCGCCTGGCTGGACGCTGCCGTGCCGCTGGCCACGGTGGTGCTCGACTGCAGCGACAACTTCGCCACGCGCCACG
CCATCAACCGTGCCTGCGCGGCGCATCGCATCCCGCTCGTGTCGGGCGCCGCGCTGCGCTTCGACGGCCAGATCAGCACC
TTCGACTTCCGCGACGCGGCCTCGCCCTGCTATGCCTGCGTGTTTCCCGAGGACCAGCCGTTCGAGGAGGTGGCCTGCTC
GACCATGGGGGTGTTCGCGCCGACCGTCGGCATCATCGGCGCGATGCAGGCCGCCGAGGCGCTGCGCGTGATCGGCGGCA
TCGGCCAGACGCTGGTGGGAAGGCTGATGATGCTCGATTCGCTGCGCATGGAATGGAACACGATGCGCATCGCACGGCAG
CCCGATTGCCCGGTCTGCGGCGGCACGCACTGA

Upstream 100 bases:

>100_bases
GCGCGGCACGCGGCCCGTGCCCGGCCTGACGCCGCGCACGCGGGCACCGCGCGAACCCGCCTAGAATAGCGGCACGGCAC
TTCCCACCCGCCCCTCCGCG

Downstream 100 bases:

>100_bases
GCCCGGCGCGCGCGGCCCGAAAAGCCGCCGCGCGGAAAGACCCGGCGGGCCGCCGGCCGCCGCGTCGAGGCCGCGAGTTC
GAGGCGCAAGGCGAGGCAGC

Product: HesA/MoeB/ThiF family protein

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNDEQLLRYSRHILVDEIGIEAQQRFLDAHALIVGAGGLGSPAAMYLAAAGVGAITLVDADTVDLTNLQRQILHATESVG
RRKVESGREALARLNPEIVVHAVAERVGAAWLDAAVPLATVVLDCSDNFATRHAINRACAAHRIPLVSGAALRFDGQIST
FDFRDAASPCYACVFPEDQPFEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGQTLVGRLMMLDSLRMEWNTMRIARQ
PDCPVCGGTH

Sequences:

>Translated_250_residues
MNDEQLLRYSRHILVDEIGIEAQQRFLDAHALIVGAGGLGSPAAMYLAAAGVGAITLVDADTVDLTNLQRQILHATESVG
RRKVESGREALARLNPEIVVHAVAERVGAAWLDAAVPLATVVLDCSDNFATRHAINRACAAHRIPLVSGAALRFDGQIST
FDFRDAASPCYACVFPEDQPFEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGQTLVGRLMMLDSLRMEWNTMRIARQ
PDCPVCGGTH
>Mature_250_residues
MNDEQLLRYSRHILVDEIGIEAQQRFLDAHALIVGAGGLGSPAAMYLAAAGVGAITLVDADTVDLTNLQRQILHATESVG
RRKVESGREALARLNPEIVVHAVAERVGAAWLDAAVPLATVVLDCSDNFATRHAINRACAAHRIPLVSGAALRFDGQIST
FDFRDAASPCYACVFPEDQPFEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGQTLVGRLMMLDSLRMEWNTMRIARQ
PDCPVCGGTH

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=249, Percent_Identity=40.5622489959839, Blast_Score=167, Evalue=6e-42,
Organism=Homo sapiens, GI4885649, Length=169, Percent_Identity=30.1775147928994, Blast_Score=81, Evalue=9e-16,
Organism=Escherichia coli, GI1787048, Length=250, Percent_Identity=43.6, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI87082356, Length=250, Percent_Identity=44.8, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1789177, Length=149, Percent_Identity=38.255033557047, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540406, Length=258, Percent_Identity=38.7596899224806, Blast_Score=192, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI193203301, Length=166, Percent_Identity=27.710843373494, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI86565433, Length=134, Percent_Identity=29.8507462686567, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI86565431, Length=134, Percent_Identity=29.8507462686567, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321903, Length=250, Percent_Identity=35.6, Blast_Score=155, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6320598, Length=169, Percent_Identity=25.4437869822485, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322639, Length=160, Percent_Identity=27.5, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582879, Length=248, Percent_Identity=41.1290322580645, Blast_Score=193, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24660640, Length=160, Percent_Identity=31.875, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28573937, Length=159, Percent_Identity=30.8176100628931, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 26691; Mature: 26691

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDEQLLRYSRHILVDEIGIEAQQRFLDAHALIVGAGGLGSPAAMYLAAAGVGAITLVDA
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHEEEEECCCCCCHHHHHHHHCCCCEEEEEEC
DTVDLTNLQRQILHATESVGRRKVESGREALARLNPEIVVHAVAERVGAAWLDAAVPLAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VVLDCSDNFATRHAINRACAAHRIPLVSGAALRFDGQISTFDFRDAASPCYACVFPEDQP
EEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEECCCCCCCCEEEEECCCCCC
FEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGQTLVGRLMMLDSLRMEWNTMRIARQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEECC
PDCPVCGGTH
CCCCCCCCCC
>Mature Secondary Structure
MNDEQLLRYSRHILVDEIGIEAQQRFLDAHALIVGAGGLGSPAAMYLAAAGVGAITLVDA
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHEEEEECCCCCCHHHHHHHHCCCCEEEEEEC
DTVDLTNLQRQILHATESVGRRKVESGREALARLNPEIVVHAVAERVGAAWLDAAVPLAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VVLDCSDNFATRHAINRACAAHRIPLVSGAALRFDGQISTFDFRDAASPCYACVFPEDQP
EEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEECCCCCCCCEEEEECCCCCC
FEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGQTLVGRLMMLDSLRMEWNTMRIARQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEECC
PDCPVCGGTH
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503 [H]