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The map label for this gene is lptA [H]

Identifier: 238028655

GI number: 238028655

Start: 3547627

End: 3548298

Strand: Direct

Name: lptA [H]

Synonym: bglu_1g31190

Alternate gene names: 238028655

Gene position: 3547627-3548298 (Clockwise)

Preceding gene: 238028654

Following gene: 238028656

Centisome position: 90.81

GC content: 69.05

Gene sequence:

>672_bases
ATGAACGAATCGTTCCCTTGTTTTTCCTACGGCAGCGCCCGCCGCGCTGTCCGCGCCGGGCTTGCCGCGGCGCTCGTCGC
GCTGCTGCTGCCGGGCGTCGCGCCGGTGGCGCACGCGGAAAAGGCGGACCAGAACAAGCCGATCCAGGTCGAGGCGGACA
ACCTGACCTATGACGACCTGAAGCAGGTGACGGTCGCGACCGGCAACGTCGTGATCACCAAAGGCACGATCCTGATCAAG
GGCGACCGCGTCGAAGTGCGCCAGGACCCGCAGGGCTATCAGTACGCCACCGCCACCATGGCGCCCGGCAGCAAGAAGCA
CGCCTCGTTCCGCCAGAAGCGCGAGGGGCTCGACGAATACATCGACGGCGACGCCGAGCGCATCGACTACGACGGCAAGC
AGGACCTGACCACGCTCACGCGCGACGCCACCGTGCGGCGCCTGCAGGGTCTGTCGACGGTCGCCGACACGGTGCATGGC
AGCGTGATCACCTATGACGGCCAGCACGACTTCTATACCGCGAAGGGCGGCAGCGACGTCTCCGCGCCGGGCAACCCGAC
CGGCCGCGTGCGCGCGATGCTCTCGCCGAAGACGGGCGGCCCGGCGCCGCTGAACGGCACCGGCGCGACGCTCGCGCCGT
CGAACAGCATGCAGGGGGGCACCAATCCGTGA

Upstream 100 bases:

>100_bases
GGTCATCGACCTTTACGGCAACGTCCGCGGCACGATCGCCGCGTCCGACGTCTCCGGCGGCGCTTCCCGCCAATCCAAGT
AACCCAGCTTGCGTGACTGC

Downstream 100 bases:

>100_bases
ACGCCCTGCCCAATCGCCAGCCGGCCGGCACCACCAGTTCGCTCGTGGTGCGCAATCTGAAAAAGCGCTACGGCTCGCGC
ACCGTCGTCAAGGACGTGTC

Product: OstA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MNESFPCFSYGSARRAVRAGLAAALVALLLPGVAPVAHAEKADQNKPIQVEADNLTYDDLKQVTVATGNVVITKGTILIK
GDRVEVRQDPQGYQYATATMAPGSKKHASFRQKREGLDEYIDGDAERIDYDGKQDLTTLTRDATVRRLQGLSTVADTVHG
SVITYDGQHDFYTAKGGSDVSAPGNPTGRVRAMLSPKTGGPAPLNGTGATLAPSNSMQGGTNP

Sequences:

>Translated_223_residues
MNESFPCFSYGSARRAVRAGLAAALVALLLPGVAPVAHAEKADQNKPIQVEADNLTYDDLKQVTVATGNVVITKGTILIK
GDRVEVRQDPQGYQYATATMAPGSKKHASFRQKREGLDEYIDGDAERIDYDGKQDLTTLTRDATVRRLQGLSTVADTVHG
SVITYDGQHDFYTAKGGSDVSAPGNPTGRVRAMLSPKTGGPAPLNGTGATLAPSNSMQGGTNP
>Mature_223_residues
MNESFPCFSYGSARRAVRAGLAAALVALLLPGVAPVAHAEKADQNKPIQVEADNLTYDDLKQVTVATGNVVITKGTILIK
GDRVEVRQDPQGYQYATATMAPGSKKHASFRQKREGLDEYIDGDAERIDYDGKQDLTTLTRDATVRRLQGLSTVADTVHG
SVITYDGQHDFYTAKGGSDVSAPGNPTGRVRAMLSPKTGGPAPLNGTGATLAPSNSMQGGTNP

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 23547; Mature: 23547

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESFPCFSYGSARRAVRAGLAAALVALLLPGVAPVAHAEKADQNKPIQVEADNLTYDDL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEECCCCHHHH
KQVTVATGNVVITKGTILIKGDRVEVRQDPQGYQYATATMAPGSKKHASFRQKREGLDEY
HEEEEECCCEEEEECEEEEECCEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
IDGDAERIDYDGKQDLTTLTRDATVRRLQGLSTVADTVHGSVITYDGQHDFYTAKGGSDV
HCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCCCC
SAPGNPTGRVRAMLSPKTGGPAPLNGTGATLAPSNSMQGGTNP
CCCCCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MNESFPCFSYGSARRAVRAGLAAALVALLLPGVAPVAHAEKADQNKPIQVEADNLTYDDL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEECCCCHHHH
KQVTVATGNVVITKGTILIKGDRVEVRQDPQGYQYATATMAPGSKKHASFRQKREGLDEY
HEEEEECCCEEEEECEEEEECCEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
IDGDAERIDYDGKQDLTTLTRDATVRRLQGLSTVADTVHGSVITYDGQHDFYTAKGGSDV
HCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCCCC
SAPGNPTGRVRAMLSPKTGGPAPLNGTGATLAPSNSMQGGTNP
CCCCCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]