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The map label for this gene is ubiB [H]

Identifier: 238028616

GI number: 238028616

Start: 3500848

End: 3502425

Strand: Reverse

Name: ubiB [H]

Synonym: bglu_1g30800

Alternate gene names: 238028616

Gene position: 3502425-3500848 (Counterclockwise)

Preceding gene: 238028617

Following gene: 238028615

Centisome position: 89.66

GC content: 66.35

Gene sequence:

>1578_bases
ATGCGCATTTTCCGTTTCATCAAAATCGTCTACACCGTGATCCGCTTCGGCCTCGACGAGGTCATGCTGTCGCGCATCGA
CGATCGTCGCGTCAAGCTGCTGCTGCGCATCACCACCATTGGGCGCCGCTTCTCCGATCCGCCGGCGGTGCGGCTGCGCC
ACGCGCTCGAAAGTCTCGGCCCGATCTTCGTGAAGTTCGGCCAGGTGCTGTCCACGCGCCGCGATTTGCTGCCCGTCGAT
TTCGCGATCGAACTCGCGAAGCTGCAGGACCAGGTGCCGCCGTTCGATTCGGCGGTGGCCATGTCGATCGTCGAGAAGTC
GCTCGGCGCGCCGATCAGCGCGTTCTTCGACGAATTCGATCCGGTGCCGGTGGCGAGCGCGTCGATCGCGCAGGTGCACT
TCGCGAAGCTGAAGCAGGGCGTGCACGCCGGCAAGCCGGTGGCCGTCAAGGTGCTGCGCCCGAACATGCTGCCGGTGATC
GATTCCGACATGGCGCTGTTGCGCGACATCGCGATCTGGGCCGAGCGGCTCTGGCCGGACGGCCGGCGCCTGAAGCCGCG
CGAGGTGGTGGCCGAATTCGACAAGTACCTGCACGACGAGCTCGACCTGATGCGCGAGGCCGCCAACGGCAGCCAGCTGC
GCCGCAACTTCGCCGGGCTCGACATCCTGCTGGTGCCCGAGATGTTCTGGGATTTCAGCTCGCAGTCGGTGCTCGTGATG
GAGCGCATGTCGGGCGTGCCGATCAGCCAGATCGACACGCTGCGCGCGGCCGGCGTCGATATCCCGAAGCTCGCGCGCGA
GGGCGTGGAGATCTTCTTCACGCAGGTGTTCCGCGACGGCTTCTTCCATGCCGACATGCACCCGGGCAACATCCAGGTCA
GCCTCGATCCGCAGCATTTCGGCCGCTACATCGCGCTCGACTTCGGGATCGTCGGCGCGCTGTCCGACTTCGACAAGAAC
TACCTCGCGCAGAACTTCCTCGCGTTCTTCAAGCGCGACTACCACCGTGTCGCGACGCTGCATCTGGAGTCGGGCTGGGT
GCCGCCCAACACGCGCGTCGAGGAGCTCGAAAGCGCGATCCGCGCGGTCTGCGAGCCGTACTTCGACCGTGCGCTGAAGG
ACATCTCGCTCGGCCAGGTGCTGATGCGGCTGTTCTCCACTTCGCGCCGCTTCAACGTCGAGATCCAGCCGCAACTCGTG
CTGCTGCAGAAGACCATGCTGAACGTCGAGGGGCTCGGCCGCTCGCTCGACCCCGAGCTGGACCTCTGGAAGACGGCCAA
GCCCTATCTCGAACGCTGGATGGCCGAGCAGATCGGCCTGCGCGGCTGGTACGAGCGCTTCAAGGTCGAGGCGCCGCAAT
GGAGCAAGACGCTGCCGCAGCTGCCGCGCCTGATCCATCATGCCCTGGCGGAGCGGCAACATGCGCCGCGCACGGTCACC
GACGACCTGATGCAGCAGATCCTGATCGAGCAGAAGCGCACCAACCGGCTGCTGCAGGCGCTGCTGGTGTTCGGCCTCGC
GGTCGGCGTCGGGGCGATCGTCGCGCGCGTGCTGCTCGCGCTCGCGGCCGGCGCCTGA

Upstream 100 bases:

>100_bases
GCGCTGGCCCGCATCGAAAAGCGGGTCGAGCGCCTGGAACAACGATCCGGCGCGCCGGCGGGCGGCAGCCCGCGCGGCGT
GAACTGAGGGGCCGCACCGC

Downstream 100 bases:

>100_bases
CCCGGGAGCGGCCGTGAGCGAGCGCCGCCGCAAGCCGGACGACGTCGCGGTGCCGCCGGACGGCGCGGCGGGCGCCGGCT
TCGTGCATCGCGACCCGGGC

Product: putative ubiquinone biosynthesis protein UbiB

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MRIFRFIKIVYTVIRFGLDEVMLSRIDDRRVKLLLRITTIGRRFSDPPAVRLRHALESLGPIFVKFGQVLSTRRDLLPVD
FAIELAKLQDQVPPFDSAVAMSIVEKSLGAPISAFFDEFDPVPVASASIAQVHFAKLKQGVHAGKPVAVKVLRPNMLPVI
DSDMALLRDIAIWAERLWPDGRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDILLVPEMFWDFSSQSVLVM
ERMSGVPISQIDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPQHFGRYIALDFGIVGALSDFDKN
YLAQNFLAFFKRDYHRVATLHLESGWVPPNTRVEELESAIRAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLV
LLQKTMLNVEGLGRSLDPELDLWKTAKPYLERWMAEQIGLRGWYERFKVEAPQWSKTLPQLPRLIHHALAERQHAPRTVT
DDLMQQILIEQKRTNRLLQALLVFGLAVGVGAIVARVLLALAAGA

Sequences:

>Translated_525_residues
MRIFRFIKIVYTVIRFGLDEVMLSRIDDRRVKLLLRITTIGRRFSDPPAVRLRHALESLGPIFVKFGQVLSTRRDLLPVD
FAIELAKLQDQVPPFDSAVAMSIVEKSLGAPISAFFDEFDPVPVASASIAQVHFAKLKQGVHAGKPVAVKVLRPNMLPVI
DSDMALLRDIAIWAERLWPDGRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDILLVPEMFWDFSSQSVLVM
ERMSGVPISQIDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPQHFGRYIALDFGIVGALSDFDKN
YLAQNFLAFFKRDYHRVATLHLESGWVPPNTRVEELESAIRAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLV
LLQKTMLNVEGLGRSLDPELDLWKTAKPYLERWMAEQIGLRGWYERFKVEAPQWSKTLPQLPRLIHHALAERQHAPRTVT
DDLMQQILIEQKRTNRLLQALLVFGLAVGVGAIVARVLLALAAGA
>Mature_525_residues
MRIFRFIKIVYTVIRFGLDEVMLSRIDDRRVKLLLRITTIGRRFSDPPAVRLRHALESLGPIFVKFGQVLSTRRDLLPVD
FAIELAKLQDQVPPFDSAVAMSIVEKSLGAPISAFFDEFDPVPVASASIAQVHFAKLKQGVHAGKPVAVKVLRPNMLPVI
DSDMALLRDIAIWAERLWPDGRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDILLVPEMFWDFSSQSVLVM
ERMSGVPISQIDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPQHFGRYIALDFGIVGALSDFDKN
YLAQNFLAFFKRDYHRVATLHLESGWVPPNTRVEELESAIRAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLV
LLQKTMLNVEGLGRSLDPELDLWKTAKPYLERWMAEQIGLRGWYERFKVEAPQWSKTLPQLPRLIHHALAERQHAPRTVT
DDLMQQILIEQKRTNRLLQALLVFGLAVGVGAIVARVLLALAAGA

Specific function: Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis [H]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC1 family. UbiB subfamily [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=262, Percent_Identity=30.9160305343511, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI41393593, Length=276, Percent_Identity=30.7971014492754, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI217035081, Length=217, Percent_Identity=31.3364055299539, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI32261307, Length=318, Percent_Identity=28.6163522012579, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI34147522, Length=281, Percent_Identity=26.6903914590747, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367309, Length=525, Percent_Identity=48.3809523809524, Blast_Score=494, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI17559152, Length=280, Percent_Identity=29.2857142857143, Blast_Score=129, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI32565180, Length=200, Percent_Identity=32, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6325148, Length=439, Percent_Identity=25.9681093394077, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323282, Length=245, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6321319, Length=236, Percent_Identity=26.6949152542373, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI22024280, Length=272, Percent_Identity=30.5147058823529, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24662575, Length=318, Percent_Identity=29.2452830188679, Blast_Score=115, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR010232 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 59659; Mature: 59659

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFRFIKIVYTVIRFGLDEVMLSRIDDRRVKLLLRITTIGRRFSDPPAVRLRHALESLG
CHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
PIFVKFGQVLSTRRDLLPVDFAIELAKLQDQVPPFDSAVAMSIVEKSLGAPISAFFDEFD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHCCC
PVPVASASIAQVHFAKLKQGVHAGKPVAVKVLRPNMLPVIDSDMALLRDIAIWAERLWPD
CCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCC
GRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDILLVPEMFWDFSSQSVLVM
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEHHHHHCCCCCCCHHH
ERMSGVPISQIDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPQHF
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHH
GRYIALDFGIVGALSDFDKNYLAQNFLAFFKRDYHRVATLHLESGWVPPNTRVEELESAI
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH
RAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLVLLQKTMLNVEGLGRSLDPEL
HHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCC
DLWKTAKPYLERWMAEQIGLRGWYERFKVEAPQWSKTLPQLPRLIHHALAERQHAPRTVT
HHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
DDLMQQILIEQKRTNRLLQALLVFGLAVGVGAIVARVLLALAAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIFRFIKIVYTVIRFGLDEVMLSRIDDRRVKLLLRITTIGRRFSDPPAVRLRHALESLG
CHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
PIFVKFGQVLSTRRDLLPVDFAIELAKLQDQVPPFDSAVAMSIVEKSLGAPISAFFDEFD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHCCC
PVPVASASIAQVHFAKLKQGVHAGKPVAVKVLRPNMLPVIDSDMALLRDIAIWAERLWPD
CCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCC
GRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDILLVPEMFWDFSSQSVLVM
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEHHHHHCCCCCCCHHH
ERMSGVPISQIDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPQHF
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHH
GRYIALDFGIVGALSDFDKNYLAQNFLAFFKRDYHRVATLHLESGWVPPNTRVEELESAI
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH
RAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLVLLQKTMLNVEGLGRSLDPEL
HHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCC
DLWKTAKPYLERWMAEQIGLRGWYERFKVEAPQWSKTLPQLPRLIHHALAERQHAPRTVT
HHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
DDLMQQILIEQKRTNRLLQALLVFGLAVGVGAIVARVLLALAAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA