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The map label for this gene is rmlA1 [C]

Identifier: 238028600

GI number: 238028600

Start: 3482691

End: 3483437

Strand: Direct

Name: rmlA1 [C]

Synonym: bglu_1g30640

Alternate gene names: 238028600

Gene position: 3482691-3483437 (Clockwise)

Preceding gene: 238028599

Following gene: 238028602

Centisome position: 89.15

GC content: 73.63

Gene sequence:

>747_bases
ATGACCGCCGTGCTCGATACCGCGATGATCTTCGCCGCCGGACGCGGCGAACGGATGCGCCCGCTCACCGACACCTGCCC
GAAACCGCTGCTCGAAGCCGGCGGCAAGCCGCTGATCGTCTGGCAGATCGAACGGCTTGCCGCGGCCGGCTTCACGACCA
TCGTGATCAACCATGCCTGGCTGGGCGCGCGCCTCGAGGCCGCGCTCGGCGACGGTGCGAGCTGGGGCGTGCGGCTGCGC
TATTCGGCCGAGGGCGAGGCGCTCGAAACCGCGGGCGGCATCGCGCAGGCGCTGCCGCTGCTGACCGGGGCCGGCGCGCC
CGATGCCGGCGGCACGGCGCGCTCGCCCGTGTTCCTCGCCGTCAGCGGCGACGTGTTCTGTGAATTCGACTATGCCTCGC
TGCGCGGGCACGCGGCACGGATGGCCGCGCTCGACGCGCCGGGCCTGCACCTCGTGATGGTGCCGAACCCGCCGTTCCAC
CCCGACGGCGATTTCGCGCTCGACGCCGACGGCCGGCTCTCGCTCGGCACCGACGCGCCGCGCGTCACGTTCGGCAACAT
CGGGCTCTACGACGTGCGGATGTTCGCCGACCTGCCGCGCGGCACGCGGCGCGCGCTCACGCCCTACTACCACGCGGCGA
TCGCGGCGGGCCGCGCGACCGGCGAACGGTACGAGGGGATCTGGGAAAACGTCGGCACGCCGGCGCAGCTGGCCGAACTC
GACGCGCGGCTGCGGGCTGCCCGCTAG

Upstream 100 bases:

>100_bases
ACCGGCCGCTCGCGCCGTTCGCGAACCTGCTCGACGAACTCGAGGGACAGCCGTCCGTCGAGGTCGGTTACACGTTCTGA
GCCCCTGCTCCGCCCACGCC

Downstream 100 bases:

>100_bases
CGGCCGGGCCGGCGCGGCGCGCGTGGGCGCGAACCGCCCGCGCGCGGCTTACCTTACGTCTGCGCCGCGGCACCGGTTGC
CGTGCCGTGCGCCGCCTGCC

Product: Nucleotidyl transferase

Products: dTDPglucose; Diphosphate [C]

Alternate protein names: Nucleotidyltransferase Family Protein; Mannose-1-Phosphate Guanyltransferase; Sugar-Phosphate Nucleotidyl Transferase; Nucleoside-Diphosphate-Sugar Pyrophosphorylase; Nucleotidyl Transferase Family Protein; Nucleotidyltransferase; Mannose-1-Phosphate Guanylyltransferase; Nucleotidyl Transferase Superfamily; Nucleotidyl Transferase Protein; Mannose-1-Phosphate Guanyltransferase-Related Protein; Transaldolase AB; ADP-Glucose Pyrophosphorylase; Mannose-1-Phosphate Guanyltransferase Protein; Nucleotide Phosphorylase; Nucleotidyl Transferase Family; Nucleotidyl Transferase Superfamily Protein; Sugar Phosphate Nucleotidyltransferase; Polysaccharide Biosynthesis Protein; Glucose-1-Phosphate Thymidylyltransferase; Glucose-1-Phosphate Nucleotidyltransferase; Nucleotidyltransferase Protein

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTAVLDTAMIFAAGRGERMRPLTDTCPKPLLEAGGKPLIVWQIERLAAAGFTTIVINHAWLGARLEAALGDGASWGVRLR
YSAEGEALETAGGIAQALPLLTGAGAPDAGGTARSPVFLAVSGDVFCEFDYASLRGHAARMAALDAPGLHLVMVPNPPFH
PDGDFALDADGRLSLGTDAPRVTFGNIGLYDVRMFADLPRGTRRALTPYYHAAIAAGRATGERYEGIWENVGTPAQLAEL
DARLRAAR

Sequences:

>Translated_248_residues
MTAVLDTAMIFAAGRGERMRPLTDTCPKPLLEAGGKPLIVWQIERLAAAGFTTIVINHAWLGARLEAALGDGASWGVRLR
YSAEGEALETAGGIAQALPLLTGAGAPDAGGTARSPVFLAVSGDVFCEFDYASLRGHAARMAALDAPGLHLVMVPNPPFH
PDGDFALDADGRLSLGTDAPRVTFGNIGLYDVRMFADLPRGTRRALTPYYHAAIAAGRATGERYEGIWENVGTPAQLAEL
DARLRAAR
>Mature_247_residues
TAVLDTAMIFAAGRGERMRPLTDTCPKPLLEAGGKPLIVWQIERLAAAGFTTIVINHAWLGARLEAALGDGASWGVRLRY
SAEGEALETAGGIAQALPLLTGAGAPDAGGTARSPVFLAVSGDVFCEFDYASLRGHAARMAALDAPGLHLVMVPNPPFHP
DGDFALDADGRLSLGTDAPRVTFGNIGLYDVRMFADLPRGTRRALTPYYHAAIAAGRATGERYEGIWENVGTPAQLAELD
ARLRAAR

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI11761621, Length=241, Percent_Identity=27.3858921161826, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI11761619, Length=241, Percent_Identity=27.3858921161826, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI133931050, Length=245, Percent_Identity=26.530612244898, Blast_Score=77, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6320148, Length=127, Percent_Identity=36.2204724409449, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355443, Length=128, Percent_Identity=33.59375, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644084, Length=128, Percent_Identity=33.59375, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.24 [C]

Molecular weight: Translated: 26150; Mature: 26019

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVLDTAMIFAAGRGERMRPLTDTCPKPLLEAGGKPLIVWQIERLAAAGFTTIVINHAW
CCCHHHEEEEEECCCCCCCCCCHHHCCHHHHHCCCCEEEEEEEHHHHHCCEEEEEEECCH
LGARLEAALGDGASWGVRLRYSAEGEALETAGGIAQALPLLTGAGAPDAGGTARSPVFLA
HCCEEHHHHCCCCCCCEEEEECCCCCCHHHHCHHHHHHHHHHCCCCCCCCCCCCCCEEEE
VSGDVFCEFDYASLRGHAARMAALDAPGLHLVMVPNPPFHPDGDFALDADGRLSLGTDAP
EECCEEEEECHHHHCCHHHHHEEECCCCEEEEECCCCCCCCCCCEEECCCCCEEECCCCC
RVTFGNIGLYDVRMFADLPRGTRRALTPYYHAAIAAGRATGERYEGIWENVGTPAQLAEL
EEEECCCCCEEEEEEHHCCCCCHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHH
DARLRAAR
HHHHHCCC
>Mature Secondary Structure 
TAVLDTAMIFAAGRGERMRPLTDTCPKPLLEAGGKPLIVWQIERLAAAGFTTIVINHAW
CCHHHEEEEEECCCCCCCCCCHHHCCHHHHHCCCCEEEEEEEHHHHHCCEEEEEEECCH
LGARLEAALGDGASWGVRLRYSAEGEALETAGGIAQALPLLTGAGAPDAGGTARSPVFLA
HCCEEHHHHCCCCCCCEEEEECCCCCCHHHHCHHHHHHHHHHCCCCCCCCCCCCCCEEEE
VSGDVFCEFDYASLRGHAARMAALDAPGLHLVMVPNPPFHPDGDFALDADGRLSLGTDAP
EECCEEEEECHHHHCCHHHHHEEECCCCEEEEECCCCCCCCCCCEEECCCCCEEECCCCC
RVTFGNIGLYDVRMFADLPRGTRRALTPYYHAAIAAGRATGERYEGIWENVGTPAQLAEL
EEEECCCCCEEEEEEHHCCCCCHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHH
DARLRAAR
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTTP; D-Glucose 1-phosphate; H+ [C]

Specific reaction: dTTP + D-Glucose 1-phosphate + H+ --> dTDPglucose + Diphosphate [C]

General reaction: Nucleotidyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA