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The map label for this gene is tctD [H]

Identifier: 238028534

GI number: 238028534

Start: 3394275

End: 3395033

Strand: Direct

Name: tctD [H]

Synonym: bglu_1g29980

Alternate gene names: 238028534

Gene position: 3394275-3395033 (Clockwise)

Preceding gene: 238028523

Following gene: 238028535

Centisome position: 86.89

GC content: 70.88

Gene sequence:

>759_bases
ATGCGAATCCTGATTGCCGAAGACGACAGCATACTCGCGGACGGCTTGACCCGATCACTCCGCCAGTCGGGCTATGCCGT
CGACCACGTGTGCAGCGGCGTCGACGCCGACACCGCGCTGTCGATGCAGACCTTCGACCTGCTGATCCTCGACCTCGGCC
TGCCGAAGATGCCCGGCCTGGACGTGCTGCGGCGCCTGCGCGCGCGCAATTCGGTGCTGCCGGTGCTGATCCTGACCGCC
GCCGACAGCGTCGACGAGCGCGTGAAGGGGCTCGATCTCGGCGCCGACGACTACATGGCCAAGCCGTTCGCGCTCAACGA
ACTCGAGGCGCGCGTGCGCGCGCTGACGCGGCGCGGCGCCGGGGGCGGCCCGACCGTGATCCGCCACGGCTCGCTGAGCT
TCGACCAGGTCGGCCGGCTGGCCTATGCCAACGAGCGCGTGCTCGACCTCTCGGCGCGCGAGCTCGGGCTGCTGGAAGTG
CTGCTGCAGCGCGTGGGCCGGCTCGTCTCGAAGGAGCAGCTCGTCGACCACCTCTGTGAATGGGGCGAGGAAGTCAGCAA
CAATGCGATCGAGGTGTACGTCCACCGGCTACGCAAGAAGATCGAGCCGAGCGGCGCCCGTATCGCGACCGTGCGGGGCC
TCGGCTACTGCCTCGAAAAGGCCGCGCCGGCCGCCGATCCGGCCTCGACCGGCGCCCCGGCGGGATCGGTCGGGGCAGCC
GGGGCGGTCGACCCCGCGGCGACGCCGTCGCTGCGCTGA

Upstream 100 bases:

>100_bases
GTTTGTGCAAGCCCGATTTGCGGGTTTCGCACGTCCGATCCACTCCGGAGACACCGCGCCCGCGCCACCTCGCCGTGCCG
CCGGCCCACGGCCACGCACC

Downstream 100 bases:

>100_bases
CGGGCGCCCGCGCCGCGCGCGCCACGGCCATGAGCCCGCCGCTTCGCGCCGCTCGGCGCCCCGCCGACCTGCGCGACGCC
GAACGCGACGCGCGCTACGA

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MRILIAEDDSILADGLTRSLRQSGYAVDHVCSGVDADTALSMQTFDLLILDLGLPKMPGLDVLRRLRARNSVLPVLILTA
ADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVIRHGSLSFDQVGRLAYANERVLDLSARELGLLEV
LLQRVGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEPSGARIATVRGLGYCLEKAAPAADPASTGAPAGSVGAA
GAVDPAATPSLR

Sequences:

>Translated_252_residues
MRILIAEDDSILADGLTRSLRQSGYAVDHVCSGVDADTALSMQTFDLLILDLGLPKMPGLDVLRRLRARNSVLPVLILTA
ADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVIRHGSLSFDQVGRLAYANERVLDLSARELGLLEV
LLQRVGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEPSGARIATVRGLGYCLEKAAPAADPASTGAPAGSVGAA
GAVDPAATPSLR
>Mature_252_residues
MRILIAEDDSILADGLTRSLRQSGYAVDHVCSGVDADTALSMQTFDLLILDLGLPKMPGLDVLRRLRARNSVLPVLILTA
ADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVIRHGSLSFDQVGRLAYANERVLDLSARELGLLEV
LLQRVGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEPSGARIATVRGLGYCLEKAAPAADPASTGAPAGSVGAA
GAVDPAATPSLR

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=44.954128440367, Blast_Score=180, Evalue=9e-47,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=43.1192660550459, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=39.2857142857143, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=38.0090497737557, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=36.6515837104072, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=35.9090909090909, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=34.4978165938865, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=34.6666666666667, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=32.618025751073, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=32.579185520362, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=32.7659574468085, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1787229, Length=236, Percent_Identity=30.5084745762712, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=40.8695652173913, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=28.7610619469027, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790299, Length=137, Percent_Identity=31.3868613138686, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=37.962962962963, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=27.1966527196653, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787487, Length=114, Percent_Identity=35.0877192982456, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26884; Mature: 26884

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIAEDDSILADGLTRSLRQSGYAVDHVCSGVDADTALSMQTFDLLILDLGLPKMPGL
CEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCH
DVLRRLRARNSVLPVLILTAADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGA
HHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCC
GGGPTVIRHGSLSFDQVGRLAYANERVLDLSARELGLLEVLLQRVGRLVSKEQLVDHLCE
CCCCCEEECCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGEEVSNNAIEVYVHRLRKKIEPSGARIATVRGLGYCLEKAAPAADPASTGAPAGSVGAA
HHHHHCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
GAVDPAATPSLR
CCCCCCCCCCCC
>Mature Secondary Structure
MRILIAEDDSILADGLTRSLRQSGYAVDHVCSGVDADTALSMQTFDLLILDLGLPKMPGL
CEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCH
DVLRRLRARNSVLPVLILTAADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGA
HHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCC
GGGPTVIRHGSLSFDQVGRLAYANERVLDLSARELGLLEVLLQRVGRLVSKEQLVDHLCE
CCCCCEEECCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGEEVSNNAIEVYVHRLRKKIEPSGARIATVRGLGYCLEKAAPAADPASTGAPAGSVGAA
HHHHHCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
GAVDPAATPSLR
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]