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The map label for this gene is panE [C]

Identifier: 238028440

GI number: 238028440

Start: 3292240

End: 3293283

Strand: Reverse

Name: panE [C]

Synonym: bglu_1g29040

Alternate gene names: 238028440

Gene position: 3293283-3292240 (Counterclockwise)

Preceding gene: 238028441

Following gene: 238028436

Centisome position: 84.3

GC content: 73.95

Gene sequence:

>1044_bases
GTGGCGATGCTCGCGATCTTCGGCGCGGGCACCATCGGCTGCTATCTCGGCGGCCGGCTGGCACTCGCCGGTGCCGAGGT
GGGGTTCGTCGGGCGCGCGGCGACGGGCGAGATGCTGCGCCGGCACGGTCTGACCCTGACCGACTACCAGGGCCGCGAGG
CGCAGGTGGCCGCCTCGCGGATCGTCTTCGACACCGATGCGCGGGCGCTCGCCCAGGCCGACGCGGTGCTCGTCACGGTC
AAGTGCGCGGCCACGCCTGCCGCGGCTGCCGCGCTCGAACCGATGCTGCGCCCCGGCACGGTGGTGATCAGCTTCCAGAA
CGGCGTGCGCCAGGCCGATGCGCTGCGCATCGCGTTGCCGGGCCGCACCGTGCTGGCCGGCATGGTGCCGTTCAACGTGA
TCGCGCGCGGCGACGGGGTGTTTCATCAGGGATCGGCGGGCGTGCTCGCGGTGGAGGCGTCGCCGCGGCTCGCGCCGGTG
GCCGCGGCCTTCGAGCGGGCCGGGCTGCCGCTGCAGGCGCGCGAGGACATCGTCGCCGTGCAGTGGGCCAAGCTGCTGTT
CAATCTCAACAACGCGATCAACGCGCTGGCCGCGATGCCGCTGCGCGAGCAGCTCGGCACGCGTGACTACCGGCGCTGCC
TCGCGCTCGCGCAGGCCGAGGCGCTGCGCGTGATGCGCCGCGCCGGCATCCGCCCCGCGCGGCTCACGCCGCTGCCGGCC
AGTTGGCTGCCGAGCGTGCTGTCGCTGCCCGACGCGCTGTTCATGCGGCTCGCGGGCGCGATGCTGGCCATCGATCCGCT
CGCGCGCTCGTCGATGGCCGACGACGTCGCGGCCGGCCGCGCGACCGAGGTGGACTGGCTCAACGGCGAGATCGTGCGGC
TTGCCGCCGAGTTCGGGCTCACCGCGCCGATCAACGCCCGGCTGTGCGAACTCGTGCGGCTCGCCACGCGCGACCACGCG
CGCACGCGCTGGCGCGCCGACGTGCTGCTGCACACGCTGCGCGATTCGGTTCACGATCTGCCGGTGATCGCCGACGAATC
CTGA

Upstream 100 bases:

>100_bases
GGCGTTCTTCGCCGGCCTGCGCCGCGAAGTGCGCGACGAGGTGGAACGGCGCGCGGGGCCGCCGCGCCACCGGCCGCACG
GCGCGCGGATCTGAGCGACG

Downstream 100 bases:

>100_bases
GCGGCCGCCGCGCACGGCACGGCGTCGGGCACGGCGCCCGCGCTCACCAGTTGATGTCGACGCAGAGCACCTGCATGCCG
CTCGCGCGCGGCACCGCTAT

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MAMLAIFGAGTIGCYLGGRLALAGAEVGFVGRAATGEMLRRHGLTLTDYQGREAQVAASRIVFDTDARALAQADAVLVTV
KCAATPAAAAALEPMLRPGTVVISFQNGVRQADALRIALPGRTVLAGMVPFNVIARGDGVFHQGSAGVLAVEASPRLAPV
AAAFERAGLPLQAREDIVAVQWAKLLFNLNNAINALAAMPLREQLGTRDYRRCLALAQAEALRVMRRAGIRPARLTPLPA
SWLPSVLSLPDALFMRLAGAMLAIDPLARSSMADDVAAGRATEVDWLNGEIVRLAAEFGLTAPINARLCELVRLATRDHA
RTRWRADVLLHTLRDSVHDLPVIADES

Sequences:

>Translated_347_residues
MAMLAIFGAGTIGCYLGGRLALAGAEVGFVGRAATGEMLRRHGLTLTDYQGREAQVAASRIVFDTDARALAQADAVLVTV
KCAATPAAAAALEPMLRPGTVVISFQNGVRQADALRIALPGRTVLAGMVPFNVIARGDGVFHQGSAGVLAVEASPRLAPV
AAAFERAGLPLQAREDIVAVQWAKLLFNLNNAINALAAMPLREQLGTRDYRRCLALAQAEALRVMRRAGIRPARLTPLPA
SWLPSVLSLPDALFMRLAGAMLAIDPLARSSMADDVAAGRATEVDWLNGEIVRLAAEFGLTAPINARLCELVRLATRDHA
RTRWRADVLLHTLRDSVHDLPVIADES
>Mature_346_residues
AMLAIFGAGTIGCYLGGRLALAGAEVGFVGRAATGEMLRRHGLTLTDYQGREAQVAASRIVFDTDARALAQADAVLVTVK
CAATPAAAAALEPMLRPGTVVISFQNGVRQADALRIALPGRTVLAGMVPFNVIARGDGVFHQGSAGVLAVEASPRLAPVA
AAFERAGLPLQAREDIVAVQWAKLLFNLNNAINALAAMPLREQLGTRDYRRCLALAQAEALRVMRRAGIRPARLTPLPAS
WLPSVLSLPDALFMRLAGAMLAIDPLARSSMADDVAAGRATEVDWLNGEIVRLAAEFGLTAPINARLCELVRLATRDHAR
TRWRADVLLHTLRDSVHDLPVIADES

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 36855; Mature: 36724

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMLAIFGAGTIGCYLGGRLALAGAEVGFVGRAATGEMLRRHGLTLTDYQGREAQVAASR
CCEEEEECCCHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHCCCEEECCCCCCHHHHHHE
IVFDTDARALAQADAVLVTVKCAATPAAAAALEPMLRPGTVVISFQNGVRQADALRIALP
EEEECCHHHHHHCCEEEEEEEECCCCHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEC
GRTVLAGMVPFNVIARGDGVFHQGSAGVLAVEASPRLAPVAAAFERAGLPLQAREDIVAV
CCHHHHHHCCCEEEECCCCCEECCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHH
QWAKLLFNLNNAINALAAMPLREQLGTRDYRRCLALAQAEALRVMRRAGIRPARLTPLPA
HHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
SWLPSVLSLPDALFMRLAGAMLAIDPLARSSMADDVAAGRATEVDWLNGEIVRLAAEFGL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHEEEEHHHCC
TAPINARLCELVRLATRDHARTRWRADVLLHTLRDSVHDLPVIADES
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
>Mature Secondary Structure 
AMLAIFGAGTIGCYLGGRLALAGAEVGFVGRAATGEMLRRHGLTLTDYQGREAQVAASR
CEEEEECCCHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHCCCEEECCCCCCHHHHHHE
IVFDTDARALAQADAVLVTVKCAATPAAAAALEPMLRPGTVVISFQNGVRQADALRIALP
EEEECCHHHHHHCCEEEEEEEECCCCHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEC
GRTVLAGMVPFNVIARGDGVFHQGSAGVLAVEASPRLAPVAAAFERAGLPLQAREDIVAV
CCHHHHHHCCCEEEECCCCCEECCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHH
QWAKLLFNLNNAINALAAMPLREQLGTRDYRRCLALAQAEALRVMRRAGIRPARLTPLPA
HHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
SWLPSVLSLPDALFMRLAGAMLAIDPLARSSMADDVAAGRATEVDWLNGEIVRLAAEFGL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHEEEEHHHCC
TAPINARLCELVRLATRDHARTRWRADVLLHTLRDSVHDLPVIADES
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]