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The map label for this gene is hutH [H]

Identifier: 238028070

GI number: 238028070

Start: 2867474

End: 2868997

Strand: Reverse

Name: hutH [H]

Synonym: bglu_1g25210

Alternate gene names: 238028070

Gene position: 2868997-2867474 (Counterclockwise)

Preceding gene: 238028071

Following gene: 238028069

Centisome position: 73.44

GC content: 70.8

Gene sequence:

>1524_bases
ATGATCACGTTGACCCCCGGCCATCTGACGCTCGCCCAGCTTCGCTCGATCGCCCGCGAGAACGTGCGCATCGAGCTCGA
TCCCGCCAGCTTCGCGGCGATCGATCGCGGCGCGCAGGCGGTGGCCGACATCGCGGCGAAGGGCGAGCCCGCCTACGGCA
TCAATACCGGCTTCGGCCGCCTCGCCAGCACCCACATCCCGCACGACCAGCTCGAACTGCTGCAGAAGAACCTGGTGCTG
TCGCACGCGGTGGGCGTGGGCGAGCCGATGAAGCCGGCGGTGGTGCGCCTGCTGATTGCGCTGAAGCTGTCGAGCCTCGG
GCGCGGCCATTCGGGCATCCGCCGCGAGGTGATGAACGCGCTCGTCACGCTTTTCAACGCCGACGTGCTGCCGCTGATCC
CGGTGAAGGGCTCGGTCGGCGCCTCGGGCGACCTGGCGCCGCTCGCCCACATGTCGGCCACGCTGCTCGGCATCGGCGAG
GTGTTGGTGCGCGGCGAACGCGCGAGCGCGGCCGACGGGCTGCGCTCGGTCGGCCTCGCGCCGCTCACGCTGCAGGCCAA
GGAAGGCCTCGCGCTGCTGAACGGCACCCAGGCCTCCACGGCGCTCGCGCTCGACAACCTGTTTGCGATCGAGGATCTCT
ACCGCAGCGCGCTGGTGGCGGGCGCGCTGTCGGTGGACGCCGCGGCCGGCTCGGTCAAGCCGTTCGACGCGCGCATCCAC
GCACTGCGCGGCCATCGCGGCCAGATCGACGCGGCCGCGGCCTATCGCGCGCTGCTCGACGGCTCGCAGATCAACCTCTC
GCATCAGGATTGCGAGAAGGTGCAGGACCCGTACAGCCTGCGCTGCCAGCCGCAGGTGATGGGCGCCTGCCTGGACCAGA
TGCGCCACGCGGCCGAGGTGCTGCTGGTCGAGGCGAACGCCGTGTCCGACAACCCGCTGATCTTCCCCGACACGGGCGAG
GTGCTGTCGGGCGGCAACTTCCACGCCGAGCCGGTGGCGTTCGCGGCCGACAACCTCGCGCTGGCCGCTGCCGAAATCGG
CGCGCTCGCCGAGCGCCGCATCGCGCTCTTGATCGACACCACGCTGTCGGGCCTGCCGCCGTTCCTCGTCAAGGATGGCG
GCGTCAATTCGGGCTTCATGATCGCCCACGTCACGGCCGCCGCACTGGCCTCCGAGAACAAGACGCTCGCGCATCCGGCC
TCGGTCGATTCGCTGCCGACCTCGGCCAACCAGGAGGACCACGTCTCGATGGCGACCTTCGCGGCGCGCAAGCTCGGCGA
CATCGCCGAGAACGTCGCCGCCATCATCGCGATCGAGCTGCTGGCCGCCGCGCAGGGCGTGGACCTGCGCCAGCCGCACG
AGACCAGCCCGGCGCTCGCCAAGGCGATGCGGGTGATCCGCGAGCAGGTGCCGCACTACGACCTCGACCGCTACTTCGCG
CCCGATATCGCGTCGATCACGCAGCTGGTGCGCGCCGGCGCGTTCGCCGCGCTGAGCCCGCTGTCGTTCGCCTCGGAGCA
GTAA

Upstream 100 bases:

>100_bases
AGGGAAATCCCTGACGAGGGAATATTGAAAACGAATTGTCTATACAAGTTGGTGCATCTACACTGATGCGCATCTCACTT
GTATAGACAGGACGCCTTTC

Downstream 100 bases:

>100_bases
GGCGATGAAGCCGCCCGCCTATCAGGAGATCAAGGATTTCATCCTGGGCCGGATCCATGCGGGCGAGTGGGGCGAGGGCG
ATCAGGTGCCGTCCGAGAAC

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: Histidase [H]

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MITLTPGHLTLAQLRSIARENVRIELDPASFAAIDRGAQAVADIAAKGEPAYGINTGFGRLASTHIPHDQLELLQKNLVL
SHAVGVGEPMKPAVVRLLIALKLSSLGRGHSGIRREVMNALVTLFNADVLPLIPVKGSVGASGDLAPLAHMSATLLGIGE
VLVRGERASAADGLRSVGLAPLTLQAKEGLALLNGTQASTALALDNLFAIEDLYRSALVAGALSVDAAAGSVKPFDARIH
ALRGHRGQIDAAAAYRALLDGSQINLSHQDCEKVQDPYSLRCQPQVMGACLDQMRHAAEVLLVEANAVSDNPLIFPDTGE
VLSGGNFHAEPVAFAADNLALAAAEIGALAERRIALLIDTTLSGLPPFLVKDGGVNSGFMIAHVTAAALASENKTLAHPA
SVDSLPTSANQEDHVSMATFAARKLGDIAENVAAIIAIELLAAAQGVDLRQPHETSPALAKAMRVIREQVPHYDLDRYFA
PDIASITQLVRAGAFAALSPLSFASEQ

Sequences:

>Translated_507_residues
MITLTPGHLTLAQLRSIARENVRIELDPASFAAIDRGAQAVADIAAKGEPAYGINTGFGRLASTHIPHDQLELLQKNLVL
SHAVGVGEPMKPAVVRLLIALKLSSLGRGHSGIRREVMNALVTLFNADVLPLIPVKGSVGASGDLAPLAHMSATLLGIGE
VLVRGERASAADGLRSVGLAPLTLQAKEGLALLNGTQASTALALDNLFAIEDLYRSALVAGALSVDAAAGSVKPFDARIH
ALRGHRGQIDAAAAYRALLDGSQINLSHQDCEKVQDPYSLRCQPQVMGACLDQMRHAAEVLLVEANAVSDNPLIFPDTGE
VLSGGNFHAEPVAFAADNLALAAAEIGALAERRIALLIDTTLSGLPPFLVKDGGVNSGFMIAHVTAAALASENKTLAHPA
SVDSLPTSANQEDHVSMATFAARKLGDIAENVAAIIAIELLAAAQGVDLRQPHETSPALAKAMRVIREQVPHYDLDRYFA
PDIASITQLVRAGAFAALSPLSFASEQ
>Mature_507_residues
MITLTPGHLTLAQLRSIARENVRIELDPASFAAIDRGAQAVADIAAKGEPAYGINTGFGRLASTHIPHDQLELLQKNLVL
SHAVGVGEPMKPAVVRLLIALKLSSLGRGHSGIRREVMNALVTLFNADVLPLIPVKGSVGASGDLAPLAHMSATLLGIGE
VLVRGERASAADGLRSVGLAPLTLQAKEGLALLNGTQASTALALDNLFAIEDLYRSALVAGALSVDAAAGSVKPFDARIH
ALRGHRGQIDAAAAYRALLDGSQINLSHQDCEKVQDPYSLRCQPQVMGACLDQMRHAAEVLLVEANAVSDNPLIFPDTGE
VLSGGNFHAEPVAFAADNLALAAAEIGALAERRIALLIDTTLSGLPPFLVKDGGVNSGFMIAHVTAAALASENKTLAHPA
SVDSLPTSANQEDHVSMATFAARKLGDIAENVAAIIAIELLAAAQGVDLRQPHETSPALAKAMRVIREQVPHYDLDRYFA
PDIASITQLVRAGAFAALSPLSFASEQ

Specific function: Unknown

COG id: COG2986

COG function: function code E; Histidine ammonia-lyase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAL/histidase family [H]

Homologues:

Organism=Homo sapiens, GI4504333, Length=494, Percent_Identity=44.9392712550607, Blast_Score=422, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17567831, Length=473, Percent_Identity=44.3974630021142, Blast_Score=384, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005921
- InterPro:   IPR008948
- InterPro:   IPR001106
- InterPro:   IPR022313 [H]

Pfam domain/function: PF00221 PAL [H]

EC number: =4.3.1.3 [H]

Molecular weight: Translated: 52944; Mature: 52944

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00488 PAL_HISTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLTPGHLTLAQLRSIARENVRIELDPASFAAIDRGAQAVADIAAKGEPAYGINTGFGR
CEEECCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LASTHIPHDQLELLQKNLVLSHAVGVGEPMKPAVVRLLIALKLSSLGRGHSGIRREVMNA
HHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LVTLFNADVLPLIPVKGSVGASGDLAPLAHMSATLLGIGEVLVRGERASAADGLRSVGLA
HHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCC
PLTLQAKEGLALLNGTQASTALALDNLFAIEDLYRSALVAGALSVDAAAGSVKPFDARIH
CEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ALRGHRGQIDAAAAYRALLDGSQINLSHQDCEKVQDPYSLRCQPQVMGACLDQMRHAAEV
HHCCCCCCCHHHHHHHHHHCCCEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHE
LLVEANAVSDNPLIFPDTGEVLSGGNFHAEPVAFAADNLALAAAEIGALAERRIALLIDT
EEEEECCCCCCCEEECCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCEEEEEEC
TLSGLPPFLVKDGGVNSGFMIAHVTAAALASENKTLAHPASVDSLPTSANQEDHVSMATF
HHCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AARKLGDIAENVAAIIAIELLAAAQGVDLRQPHETSPALAKAMRVIREQVPHYDLDRYFA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCC
PDIASITQLVRAGAFAALSPLSFASEQ
CCHHHHHHHHHHCHHHHHCCCHHCCCC
>Mature Secondary Structure
MITLTPGHLTLAQLRSIARENVRIELDPASFAAIDRGAQAVADIAAKGEPAYGINTGFGR
CEEECCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LASTHIPHDQLELLQKNLVLSHAVGVGEPMKPAVVRLLIALKLSSLGRGHSGIRREVMNA
HHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LVTLFNADVLPLIPVKGSVGASGDLAPLAHMSATLLGIGEVLVRGERASAADGLRSVGLA
HHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCC
PLTLQAKEGLALLNGTQASTALALDNLFAIEDLYRSALVAGALSVDAAAGSVKPFDARIH
CEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ALRGHRGQIDAAAAYRALLDGSQINLSHQDCEKVQDPYSLRCQPQVMGACLDQMRHAAEV
HHCCCCCCCHHHHHHHHHHCCCEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHE
LLVEANAVSDNPLIFPDTGEVLSGGNFHAEPVAFAADNLALAAAEIGALAERRIALLIDT
EEEEECCCCCCCEEECCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCEEEEEEC
TLSGLPPFLVKDGGVNSGFMIAHVTAAALASENKTLAHPASVDSLPTSANQEDHVSMATF
HHCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AARKLGDIAENVAAIIAIELLAAAQGVDLRQPHETSPALAKAMRVIREQVPHYDLDRYFA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCC
PDIASITQLVRAGAFAALSPLSFASEQ
CCHHHHHHHHHHCHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA