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The map label for this gene is trpS [H]

Identifier: 238027992

GI number: 238027992

Start: 2773587

End: 2774789

Strand: Reverse

Name: trpS [H]

Synonym: bglu_1g24410

Alternate gene names: 238027992

Gene position: 2774789-2773587 (Counterclockwise)

Preceding gene: 238027993

Following gene: 238027991

Centisome position: 71.03

GC content: 65.17

Gene sequence:

>1203_bases
ATGTTCCCCGATCGTATCTTTTCCGGCATGCGTCCCACCGGGTCGCTGCATCTCGGCCATTACCACGGCGTGTTGAAGAA
TTGGGCGAAGCTGCAGTCCGAGTATCCGTGCTTCTTCTGCGTGGTCGACTGGCATGCGCTGACCACGCATTACGAAACCC
CCGAGGTGATCGAGAAGAACGTCTGGGAAGTGCTGATCGACTGGATCGCCGCCGGCATCGATCCGACCCAGGCCACGCTG
TTCATCCAGAGCAAGGTGCCGGAGCATGCCGAACTGGCGCTGCTGCTCGGCATGAGCACGCCGCTGGGCTGGCTCGAACG
GGTGCCGACCTACAAGGAGCAGATCGAGAAGCTGCGCGACAAGGACCTGTCCACCTACGGCTTTCTCGGCTACCCGGTGC
TGATGGCAGCCGACATCCTGCTCTATCGCGGCTCGCTCGTGCCCGTCGGCGAGGATCAGGTGCCGCACGTCGAGATGACG
CGTGAGATCGCGCGCCGCTTCAACTACCTGTACGGCCGCGAGAAGGGCTTCGAGGAGAAGGCGCTCGAGGCCGCGAAGAA
GCTCGGCGGCAAGCGCGCCAAGCTCTATCACGAGCTGCGCAACGCCTATCAGCAGGAAGGCGACGACGAGGCGCTCGAAC
AGGCACGCGCCATGTTGCAGGAGTCGCAGAGCCTGTCGATGAGCGACCGCGAGCGGCTGTTCGGCTATCTCGAAGGCGCG
CGCAAGATCATCCTGGTCGAGCCGCAGGCGCTGCTGACCGCGGCGTCGCGGATGCCGGGGCTCGACGGCGGCAAGATGTC
GAAGTCGTACGGCAACACGATCGGGCTGCGCGAGGACGCGGAAACGATCACGAAGAAGGTGCGCACCATGCCGACCGACC
CGGCCCGCGTGCGCCGCACCGATCCGGGCGATCCCGAGAAATGCCCGGTCTGGCAGTTCCATCTCGTCTATTCGGACGAC
ACCACGCGCGAATGGGTGACGCAAGGCTGCAAGTCGGCCGGCATCGGCTGCCTCGACTGCAAGCAGCCCGTGGTCGAGGG
CATCCTGCGCGAACAGCAGCCGATGCTCGAGCGCGCGCAGAAATACATGGACGACCCCTCGCTGCTGCGCGCGATCGTGG
CCGACGGCTGCGACAAGGCACGCAAGCACGCGGTCGAGACGATGCGCGACGTGCGCGACGCGATGGGCCTGTCCTACAAC
TGA

Upstream 100 bases:

>100_bases
GTTCACGCGGATCTGGCTGGGGCCGCTGGTCGGCCTCGGCCAGAGCGTGCTGGCCGCCATCCTGAATCCCATTGCCTCGC
TTTTCTTCTAAAAGACCACC

Downstream 100 bases:

>100_bases
GCGGGCGGATGCTCCGATGACGACGTCTGCCCCTGGCGCCGCGGCCGCTTTGCCGGGCGCGCCCGACCCGGCCGTGGCTG
CCGCGCCGTCGCGCTGGGTC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MFPDRIFSGMRPTGSLHLGHYHGVLKNWAKLQSEYPCFFCVVDWHALTTHYETPEVIEKNVWEVLIDWIAAGIDPTQATL
FIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQIEKLRDKDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMT
REIARRFNYLYGREKGFEEKALEAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
RKIILVEPQALLTAASRMPGLDGGKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRTDPGDPEKCPVWQFHLVYSDD
TTREWVTQGCKSAGIGCLDCKQPVVEGILREQQPMLERAQKYMDDPSLLRAIVADGCDKARKHAVETMRDVRDAMGLSYN

Sequences:

>Translated_400_residues
MFPDRIFSGMRPTGSLHLGHYHGVLKNWAKLQSEYPCFFCVVDWHALTTHYETPEVIEKNVWEVLIDWIAAGIDPTQATL
FIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQIEKLRDKDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMT
REIARRFNYLYGREKGFEEKALEAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
RKIILVEPQALLTAASRMPGLDGGKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRTDPGDPEKCPVWQFHLVYSDD
TTREWVTQGCKSAGIGCLDCKQPVVEGILREQQPMLERAQKYMDDPSLLRAIVADGCDKARKHAVETMRDVRDAMGLSYN
>Mature_400_residues
MFPDRIFSGMRPTGSLHLGHYHGVLKNWAKLQSEYPCFFCVVDWHALTTHYETPEVIEKNVWEVLIDWIAAGIDPTQATL
FIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQIEKLRDKDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMT
REIARRFNYLYGREKGFEEKALEAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
RKIILVEPQALLTAASRMPGLDGGKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRTDPGDPEKCPVWQFHLVYSDD
TTREWVTQGCKSAGIGCLDCKQPVVEGILREQQPMLERAQKYMDDPSLLRAIVADGCDKARKHAVETMRDVRDAMGLSYN

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=189, Percent_Identity=40.2116402116402, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI41352700, Length=169, Percent_Identity=42.0118343195266, Blast_Score=137, Evalue=1e-32,
Organism=Escherichia coli, GI1789786, Length=167, Percent_Identity=45.5089820359281, Blast_Score=162, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71982800, Length=176, Percent_Identity=35.7954545454545, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71982793, Length=213, Percent_Identity=31.924882629108, Blast_Score=117, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6320474, Length=184, Percent_Identity=36.9565217391304, Blast_Score=122, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24666151, Length=172, Percent_Identity=41.2790697674419, Blast_Score=149, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 45373; Mature: 45373

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPDRIFSGMRPTGSLHLGHYHGVLKNWAKLQSEYPCFFCVVDWHALTTHYETPEVIEKN
CCCHHHHCCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCCCCHHHHHHH
VWEVLIDWIAAGIDPTQATLFIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQIEKLRD
HHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHH
KDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMTREIARRFNYLYGREKGFEEK
CCCCHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
ALEAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
RKIILVEPQALLTAASRMPGLDGGKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRT
CEEEEECCHHHHHHHHHCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCC
DPGDPEKCPVWQFHLVYSDDTTREWVTQGCKSAGIGCLDCKQPVVEGILREQQPMLERAQ
CCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KYMDDPSLLRAIVADGCDKARKHAVETMRDVRDAMGLSYN
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFPDRIFSGMRPTGSLHLGHYHGVLKNWAKLQSEYPCFFCVVDWHALTTHYETPEVIEKN
CCCHHHHCCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCCCCHHHHHHH
VWEVLIDWIAAGIDPTQATLFIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQIEKLRD
HHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHH
KDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMTREIARRFNYLYGREKGFEEK
CCCCHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
ALEAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
RKIILVEPQALLTAASRMPGLDGGKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRT
CEEEEECCHHHHHHHHHCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCC
DPGDPEKCPVWQFHLVYSDDTTREWVTQGCKSAGIGCLDCKQPVVEGILREQQPMLERAQ
CCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KYMDDPSLLRAIVADGCDKARKHAVETMRDVRDAMGLSYN
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]